Research suggests that shifts in bacterial populations within a child's mouth could provide objective biomarkers for identifying autism spectrum disorder (ASD). The findings catalyze development of a novel, saliva-based panel to aid clinicians in earlier diagnosis of ASD. Five ratios of oral microbes distinguished ASD from typically developing children (79.5 percent accuracy), three distinguished ASD from developmentally delayed, non-autistic (76.5 percent accuracy), and three distinguished ASD children with/without GI disturbance (85.7 percent accuracy).
Aging usually improves the flavor of cheese, but that's not why some very old cheese discovered in an Egyptian tomb is drawing attention. Instead, it's thought to be the most ancient solid cheese ever found, according to a study published in ACS' journal Analytical Chemistry.
A multidisciplinary study finds a way to examine biofilms with high efficiency.
Scientists have created a fluorescent probe that can tag and illuminate single specimens of the bacteria that cause tuberculosis (TB), one of the world's most problematic infectious diseases.
Scientists have used light patterns to control the swimming speed of bacteria and direct them to form different shapes.
Researchers comparing clonal strains of the mycobacteria that cause TB, before and after they developed resistance to a first-line drug, found that a single genetic change may not always have identical effects on bacterial fitness.
Hundreds of polymers -- which could kill drug-resistant superbugs in novel ways -- can be produced and tested using light, using a method developed at the University of Warwick
Francisella (F.) tularensis is a highly virulent bacterial pathogen that is resistant to environmental stresses and causes tularemia. This disease affects wild animals, especially small mammals like rodents and hares, and is colloquially known as rabbit fever. F. tularensis infections are associated with high mortality in these reservoir hosts. Humans can also suffer from tularemia, although the illness caused by the subtype F. tularensis ssp. holarctica in Europe generally disappears spontaneously after a period of weeks or months.
A new study published in the scientific journal PLOS Computational Biology led by Patrick Bradley, a postdoctoral scholar in Katherine Pollard's laboratory at the Gladstone Institutes, found a new approach to identify the genes that may be important to help microbes live successfully in the human gut.
Salk Institute researchers report that giving mice dietary iron supplements enabled them to survive a normally lethal bacterial infection and resulted in later generations of those bacteria being less virulent. The approach, which appears in the journal Cell on Aug. 9, 2018, demonstrates in preclinical studies that non-antibiotic-based strategies--such as nutritional interventions--can shift the relationship between the patient and pathogens away from antagonism and toward cooperation.