The innate immune system, our first line of defense against bacterial infection, has a side job that's equally important: fine-tuning our metabolism.
The work has important implications for understanding how human cancer cells develop resistance to natural product-based chemotherapies.
New computational simulations suggest that the effects of antibiotics on a bacterial community depend on whether neighboring species have competitive or cooperative relationships, as well as their spatial arrangement. Sylvie Estrela of Yale University and Sam Brown of the Georgia Institute of Technology present these findings in PLOS Computational Biology.
Short, synthetic peptides that disrupt bacteria's response to antibiotics boost antibiotic activity against high-density skin infections in mice, according to new research presented by Daniel Pletzer and colleagues at the University of British Columbia in Vancouver, Canada.
Research develops a better understanding of and exerts an unparalleled control of protein molecules.
New insight on how antibiotics affect the gut microbiome -- the community of microbes that live inside us -- has been published in the journal eLife.
A new study by Scripps Research, published today in Nature Communications, suggests scientists could build better drugs by learning from bacteria-derived molecules called thiocarboxylic acids.
Purdue University researchers have identified a new compound that in preliminary testing has shown itself to be as effective as antibiotics approved by the FDA to treat life-threatening infections while also appearing to be less susceptible to bacterial resistance. The compound has been potent against antibiotic-resistant pathogens such as MRSA, which is often found in hospitals and other health care settings, and vancomycin-resistant Staphylococcus, with vancomycin long considered a drug of last resort.
The discovery changes our understanding of the basic mechanism of photosynthesis and should rewrite the textbooks. It will also tailor the way we hunt for alien life and provide insights into how we could engineer more efficient crops that take advantage of longer wavelengths of light.
A thorough, terminal cleaning of hospital rooms between patients is essential for eliminating environmental contamination, and a checklist is a standard tool to guide the cleaning staff. But new research presented at the APIC 45th Annual Conference offers an important reminder that the checklist is only as good as the list itself.