In 2017, doctors from the Transplant Unit at the Wits Donald Gordon Medical Centre performed what is believed to be the world's first intentional liver transplant from a mother living with HIV to her critically ill HIV negative child, who had end-stage liver disease. Now, more than a year later, the mother and child have fully recovered, however, doctors are unsure the HIV-status of the child.
In a new study, researchers have found that the gut microbiome appears to play a key role in how well the body accepts a transplanted heart. The scientists found a causal relationship between the presence of certain microbes and transplant outcome. The results have the potential to significantly change how researchers and doctors deal with the problem of rejection and transplantation.
Nearly one in seven Americans has chronic kidney disease, and the condition accounts for about 20 percent of the spending by Medicare. A new analysis finds that providing specialized medical care and coordination to patients whose kidneys are failing before they need dialysis treatment could save the US health care system more than $1 billion annually.
In 2014, the first child to have been gestated in a donated uterus was born. Although research into uterus transplantation is still in an early phase, many see the donations as a success. Researchers at universities including Linköping University have studied ethical aspects of uterus transplantation. The results show that uterus transplantation with living donors is ethically just as problematic as altruistic surrogacy.
Future Science Group today announces the publication of a new peer-reviewed study that surveys the Canadian direct-to-consumer marketplace of companies advertising putative stem cell treatments for various clinical indications.
Two recent studies in the journal Leukemia present a new approach for bone marrow donation and transplant that preclinical laboratory tests suggest could make the life-saving procedure safer and more effective for patients. Researchers report the studies demonstrate that use of an experimental drug called CASIN in laboratory mice results in higher efficiency when harvesting blood stem cells from donors and less toxicity in transplant recipients.
An international team of researchers consisting of scientists from NUST MISIS and TU Dortmund University has developed a technology to study the behavior of orthopedic implants in laboratory conditions as close as possible to the human body. The technology is notable for its ethics: the research can be carried out in vitro -- that is, without involving lab animals. The research article has been published in the Journal of the Mechanical Behavior of Biomedical Materials.
Scientists working to bioengineer the entire human gastrointestinal system in a laboratory now report using pluripotent stem cells to grow human esophageal organoids. The newly published research in the journal Cell Stem Cell is the first time scientists have been able to grow human esophageal tissue entirely from pluripotent stem cells (PSCs), which can form any tissue type in the body.
The new system did not minimize pre-transplant dialysis exposure for patients who were not waitlisted preemptively.
Children are at a considerable disadvantage when competing with adults for livers from deceased organ donors in the US allocation system for liver transplants.