Rice University scientists develop a nano-thermometer able to take temperatures inside cells. The technique takes advantage of the fluorescent properties of a modified molecular rotor and the viscosity of the cell.
The function of the visual photopigment rhodopsin and its action in the retina to facilitate vision is well understood. However, there remain questions about other biological functions of this family of proteins (opsins) and this has ramifications for our understanding of several evolutionary pathways. Now, an international research team led by the University of Göttingen has shown there are other functions of opsin outside vision and this provides insights into how the eye evolved. Their research was published in Current Biology.
a research team at Harvard's Wyss Institute for Biologically Inspired Engineering and the Massachusetts Institute of Technology (MIT) demonstrates the use of CRISPR as a control element in a new type of stimuli-responsive "smart" materials.
September's SLAS Discovery cover article, "Using physicochemical measurements to influence better compound design,' now available for 30 days.
In new research published in the journal Science, a team of biologists, including Colorado State University Assistant Professor of Biology Marc Nishimura, have shed new light on a crucial aspect of the plant immune response. Their discovery, revealing how plant resistance proteins trigger localized cell death, could lead to new strategies for engineering disease resistance in next-generation crops.
An enzyme induced by stress to help reduce production of damaging free radicals is also used by liver cancer to regulate two major cell proliferation pathways that enable the cancer to thrive, scientists report.
A new study indicates that some exoplanets may have better conditions for life to thrive than Earth itself has. 'This is a surprising conclusion', said lead researcher Dr. Stephanie Olson, 'it shows us that conditions on some exoplanets with favorable ocean circulation patterns could be better suited to support life that is more abundant or more active than life on Earth.'
Researchers at the Paul Scherrer Institute, together with colleagues from the pharmaceutical company F. Hoffmann-La Roche AG, have taken an important step towards the development of an agent against the metastasis of certain cancers. Using the Swiss Light Source, they deciphered the structure of a receptor that plays a crucial role in the migration of cancer cells.
A team led by Texas A&M University's College of Veterinary Medicine & Biomedical Sciences' (CVM) researcher Dr. Stephen Safe has discovered a new pathway that may help suppress the development of glioblastoma tumors, one of the deadliest forms of cancer.
One way biological compounds inside cells stay organized is through membrane-less organelles (MLOs) -- wall-less liquid droplets made from proteins and RNA that clump together and stay separate from the rest of the cellular stew. In a paper in Scientific Reports, scientists report that MLOs may be highly sensitive to the level of divalent cations inside cells. This matters because divalent calcium and magnesium ions aid in cellular signaling and are vital to life.