In a new study in mice, researchers have identified a key protein involved in the irregular brain cell activity seen in autism spectrum disorders and epilepsy. The protein, p53, is well-known in cancer biology as a tumor suppressor.
Childhood adversity permanently alters the peripheral and central immune systems, increasing the sensitivity of the body's immune response to cocaine, reports a study by researchers at the IRCCS Santa Lucia Foundation and University of Rome 'La Sapienza', Italy.
Law enforcement official are most likely to ask first- or second-generation Latinos for papers proving their right to be in the US. This is according to a study published in Springer's journal Race and Social Problems. Lead author, Maria Cristina Morales of the University of Texas at El Paso in the US, says the findings are important given that US law enforcement officers are increasingly required to make distinctions between citizens and non-citizens living along the border with Mexico.
Osaka University scientists examined positions to detect motor and target errors and whether error signals from these positions were used for learning, finding that the parietal lobe detected causes of motor errors in arm reaching and provided signals to compensate for errors. They also revealed that Brodmann area 5 detected the self-generated motor error and that Brodmann area 7 detected target error caused by target movements, both providing error signals for adaptation.
White mass shooters receive much more sympathetic treatment in the media than black shooters, according to a new study that analyzed coverage of 219 attacks. Findings showed that white shooters were 95 percent more likely to be described as 'mentally ill' than black shooters.
A simple instruction to change your thinking as mealtime approaches can help cut calories, according to new research from the University of Tübingen, Germany. By encouraging study participants to concentrate on different types of information when planning their meal, the experimenters saw portion sizes shift. Adopting a health-focused mindset produced better outcomes than focusing on pleasure or the desire to fill up.
Scientists at Rutgers Brain Health Institute have discovered that a small group of brain cells in the hypothalamus called 'orexin' neurons could be a promising target for medications for controlling binge eating episodes in individuals with obesity. These neurons, named for the chemical messenger they use to communicate with other brain cells, have previously been shown to be important for addiction to several drugs, including cocaine.
A novel drug based on capsaicin, the compound that gives chili peppers their spicy burn, caused long term weight loss and improved metabolic health in mice eating a high fat diet, in new studies from the University of Wyoming School of Pharmacy. The drug, Metabocin, was designed to slowly release capsaicin throughout the day so it can exert its anti-obesity effect without producing inflammation or adverse side effects.
Hormones that signal the body's state of hunger and fullness could be the key to new treatments for drug and alcohol addiction. That is the consensus of an expert panel convened this week at the annual meeting of the Society for the Study Ingestive Behavior, the leading international research conference on food and fluid intake. Gut hormones have received considerable attention from scientists seeking to understand overeating and obesity, which led the panelists to discover that those hormones are also involved in addiction.
Improved medications for Type 2 diabetes are one step closer thanks to a new discovery reported this week by researchers at the University of Pennsylvania and Syracuse University. By modifying the key ingredient in current diabetes drugs, the researchers produced a compound that was effective for hyperglycemia in animal trials, yet without the most problematic side effects of current drugs.