Patients who take prescription opioids for more than 60 days before total knee or hip replacement surgery are at significantly higher risk of being readmitted to the hospital and of undergoing repeat joint-replacement surgery, compared to patients with no preoperative opioid use, reports a study in the July 18 issue of The Journal of Bone & Joint Surgery. The journal is published in the Lippincott portfolio in partnership with Wolters Kluwer.
Lowering the default amount of opioid pills prescribed to patients in a health care system's electronic medical record was associated with a deccrease in the amount of opioids prescribed systemwide.
Childhood adversity permanently alters the peripheral and central immune systems, increasing the sensitivity of the body's immune response to cocaine, reports a study by researchers at the IRCCS Santa Lucia Foundation and University of Rome 'La Sapienza', Italy.
Hormones that signal the body's state of hunger and fullness could be the key to new treatments for drug and alcohol addiction. That is the consensus of an expert panel convened this week at the annual meeting of the Society for the Study Ingestive Behavior, the leading international research conference on food and fluid intake. Gut hormones have received considerable attention from scientists seeking to understand overeating and obesity, which led the panelists to discover that those hormones are also involved in addiction.
The US Food and Drug Administration (FDA) created the Breakthrough Therapy designation in 2012 to expedite the development and review of drugs and biologics intended to treat serious or life-threatening conditions when preliminary clinical evidence suggested better improvement over existing therapies.
White adolescent boys experiencing early puberty are at higher risk for substance use than later developing boys, a new Purdue University study finds.
Outpatient antibiotic prescribing varied among traditional medical and retail clinic settings and during visits with respiratory diagnoses where antibiotics were inappropriate, patterns that suggest differences in patient mix and antibiotic overuse.
Lesbian, gay, bisexual or questioning (LGBQ) teens are at substantially higher risk of substance use than their heterosexual peers, according to a new study led by San Diego State University researchers and published in the American Journal of Public Health.
Among Medicaid recipients taking prescription opioids, high opioid doses and concurrent treatment with benzodiazepine sedatives are among the key, potentially modifiable risk factors for fatal overdose, reports a study in the August issue of Medical Care. The journal is published in the Lippincott portfolio by Wolters Kluwer.
A study from a research team consisting of investigators from the Mass. Department of Public Health and several academic medical centers, led by a MassGeneral Hospital for Children physician, found that opioid overdose events decreased during pregnancy, reaching their lowest level during the third trimester, but then increased during the postpartum period, becoming significantly higher during the second six months after delivery.