Baby-boomers, those born between 1947 and 1964, experienced an excess risk of prescription opioid overdose death and heroin overdose death, according to latest research at Columbia University's Mailman School of Public Health. Individuals born between 1979 and 1992 were also at significantly increased risk for death from heroin overdose. The study findings are consistent for both men and women.
Drug addiction may not require a habitual relationship with a substance, suggests findings from a new model of cocaine administration in rats that better captures the human experience of obtaining and using drugs. The research, published in JNeurosci, represents a step towards a translational animal model of addiction that challenges widely held views about drug users.
Work underway in a laboratory at the University of Delaware suggest certain drugs can prevent and reduce changes to the brain caused by mistreatment at an early age.
Researchers conducted a critical review of existing literature to determine whether social media big data can be used to understand communication and behavioral patterns related to prescription drug abuse. Their study found that with proper research methods and attention to privacy and ethical issues, social media big data can reveal important information concerning drug abuse, such as user-reported side effects, drug cravings, emotional states, and risky behaviors.
Opioid pain relievers can be extremely effective in relieving pain, but can carry a high risk of addiction and ultimately overdose when breathing is suppressed and stops. Scientists have discovered a way to separate these two effects -- pain relief and breathing -- opening a window of opportunity to make effective pain medications without the risk of respiratory failure. The research, published today in Cell, was funded by the National Institute on Drug Abuse (NIDA), part of the National Institutes of Health.
A new study shows as many as one in 20 children were still receiving codeine to treat pain after tonsil and adenoid surgery, two years after federal regulators warned doctors that prescribing the opioid to kids after the routine surgeries could be fatal.
A new study published by the scientific journal Addiction has found that a concentrated 2mg intranasal naloxone spray delivers naloxone as effectively, over the critical first 15 minutes, as the standard 0.4mg intramuscular (IM) naloxone injection. The 2mg spray also maintains blood levels of naloxone more than twice as high as the 0.4mg IM levels for two hours after administration. It should therefore be highly effective in reversing opioid overdose.
A study comparing the effectiveness of two pharmacologically distinct medications used to treat opioid use disorder -- a buprenorphine/naloxone combination and an extended release naltrexone formulation -- shows similar outcomes once medication treatment is initiated.
A new study concludes that two of the top medications available for outpatient, office-based treatment, once initiated, are equally safe and effective in curtailing opioid use, relapse, treatment drop-out and overdose.
Daily use of marijuana as well as past month rates rose for both men and women aged 26 and older in states with medical marijuana laws in effect. Marijuana use among those younger than 26 years old was generally unaffected by changes in the law.