Supplementing a single protein found in the spinal cord could help prevent symptoms of Lou Gehrig's disease, according to a new study out of Case Western Reserve University School of Medicine. Researchers found high levels of the protein -- called mitofusion 2 or Mfn2 -- prevented nerve degeneration, muscle atrophy, and paralysis in a mouse model of the disease. Since Mfn2 is often depleted during Lou Gehrig's, the new study suggests supplementing it could be a novel therapeutic approach for the disease.
- Cell Metabolism
- National Institutes of Health, Alzheimer's Association, Association for Frontotemporal Degeneration and Alzheimer's Drug Discovery Foundation, Glenn Foundation for Medical Research