In a research article '3D Nano-scale Imaging by Plasmonic Brownian Microscopy' published today in Nanophotonics, the team around Prof. Xiang Zhang from the University of California in Berkeley demonstrate a method for meeting this challenge with stunning properties.
As it squeezes down the chromatin fiber, the cohesin protein complex extrudes a growing loop of DNA -- a bit like the quick-lacing system of trail-running shoes. But what is powering the movement of the protein? A team of SIB scientists has found that the driving force could be the supercoiling of upstream DNA. Their research, published in Nucleic Acids Research, is thereby adding a key piece to the puzzle of gene expression regulation.
Measuring dosage of radiation can be challenging, especially when working with low-energy protons, but researchers have now developed an ultra-thin diamond membrane that can measure the number of protons in a radiation dose with almost perfect accuracy. The detector attaches to a charged-particle microbeam and enables the delivery of radiation to an area less than 2 micrometers wide. The study, published this week in Applied Physics Letters, represents a valuable technological advance for radiation biology.
Researchers from Mechanobiology Institute, Singapore, report that endocytosis, which was previously thought to be a random process, actually occurs in a coordinated manner through collective dynamics. The work showed how a major endocytic pathway mediated by the protein clathrin, was found to commence with periodic traveling waves of clathrin, which were coupled temporally and spatially to downstream cortical actin waves. Clathrin endocytic waves were identified as the upstream initiator of cortical actin waves.
As the Aug. 21 eclipse approached, researchers prepared to understand plants' response to light and temperature. The varied results have left the researchers with interesting questions.
Wild-derived house mice call at higher rates and frequencies during interactions with the opposite sex than with the same sex, according to a study published Dec. 13, 2017, in the open-access journal PLOS ONE by Sarah Zala from Konrad Lorenz Institute of Ethology, Austria, and colleagues.
Scientists were able to demonstrate another way of viewing biological samples at high resolution.
Researchers at the National Institute of Standards and Technology and their colleagues have demonstrated that nanometer-scale pores etched into layers of graphene can provide a simple model for the complex operation of ion channels.
Little is known about how axons in the developing visual system stabilize their connections upon reaching the correct layer, but scientists at Tokyo Institute of Technology (Tokyo Tech), led by Associate Professor Takashi Suzuki, have identified two proteins that provide layer-specific stabilization.
The fresh, unmistakable scent of a pine forest comes from a medley of chemicals produced by its trees. Researchers have now accurately determined the chemical structure of one compound in its gas phase, a molecule called alpha-pinene. The analysis can help scientists better detect and understand how alpha-pinene reacts with other gases in the atmosphere, a process that can affect health and climate. The researchers describe their analysis in this week's Journal of Chemical Physics.