In discovering how an antibiotic kills the bacteria that cause tuberculosis, scientists open the door to new treatments for the disease -- and possibly others, as well.
An international research team discovered a new type of curved light beams, dubbed a "photonic hook". Photonic hooks are unique, as their radius of curvature is two times smaller than their wavelength. This is the smallest curvature radius of electromagnetic waves ever recorded. Photonic hook can improve the resolution of optical systems and control the movement of nanoparticles, individual cells, viruses or bacteria. Results of this research were published in Optics Letters and Scientific Reports.
The gateway to cellular headquarters has 552 components. A new map that shows how all these pieces fit together could help scientists study numerous diseases.
The journal Science published the research by biologists at Emory University, showing that a process known as hemimethylation plays a role in looping DNA in a specific way. The researchers also demonstrated that hemimethylation is maintained deliberately -- not through random mistakes as previously thought -- and is passed down through human cell generations.
Fungi may be harmful pathogens. On the other hand, they are used for the production of food or medicine and in bioengineering. In either case, it is required to precisely understand their growth mechanism. Researchers of Karlsruhe Institute of Technology (KIT) have made a big step forwards: Using high-performance light microscopy, they watched mold fungi as they grew in the cell. The findings are presented in Science Advances.
Micro-sized gels are indispensable for biomedical, cosmetic, and food materials, warranting importance of controlling mechanical properties of a single microgel for application usages. Here it was shown that space sizes for gelation change mechanical properties of gelatin gels. Detailed analysis in the microgel structure revealed that changes in secondary structures of gelatin protein induced the increase of elasticity. These findings shed light on the ability of space-size as a controller of mechanical properties of gels.
One of the biggest current threats to global health is the rise of multi-drug resistant bacteria, caused by the spreading of antibiotic resistance amongst them. In an attempt to help fight this threat, EMBL researchers have unraveled the molecular basis of a major antibiotic resistance transfer mechanism. They also developed molecules and a proof-of-principle for blocking this transfer. Cell publishes their results on March 15.
University of Houston researchers link autism spectrum disorders to defects in a nuclear receptor inside the brain. And just like that, this world-renowned team advances the understanding of autism.
A research team led by an Oregon State University biophysicist and a plant biologist from University of California, Davis has discovered a novel motor protein that significantly expands current understanding of the evolution and design principle of motor proteins.
A team led by scientists from Scripps Institution of Oceanography at the University of California San Diego and the J. Craig Venter Institute (JCVI) has demonstrated that the excess carbon dioxide added to the atmosphere through the combustion of fossil fuels interferes with the health of phytoplankton which form the base of marine food webs.