'People often focus on mobility impairments associated with SCI; however, addressing cognitive deficits in this population is also critically important,' said co-author Dr. Dyson-Hudson, director of SCI Research, and director of the Northern New Jersey SCI Model System. 'Future research needs to be based on broader measures of neuropsychological function. Identifying modifiable risk factors and developing targeted cognitive interventions will help restore maximal function, and support the efforts of individuals to participate in their communities and the workforce.'
Researchers from the Netherlands Institute for Neuroscience and the Leiden University Medical Center have shown that treatment using gene therapy leads to a faster recovery after nerve damage. By combining a surgical repair procedure with gene therapy, the survival of nerve cells and regeneration of nerve fibers over a long distance was stimulated. The discovery, published in Brain, is an important step towards the development of a new treatment for people with nerve damage.
Clostridium difficile infection (CDI) is a potentially deadly infection in the large intestine most common in people who need to take antibiotics for a long period of time, particularly in Australia's ageing population. But when doses of a new antibiotic called Ramizol were given to hamsters infected with a lethal dose of the bacteria, a significant proportion of hamsters survived the infection.
UCLA and UC San Francisco biologists have discovered a dramatic pattern of bone growth in female mice -- research that could potentially lead to stronger bone density in women and new treatments for osteoporosis in older women. The researchers found that blocking a set of signals from a small number of neurons in the brain causes female mice to build super-strong bones and maintain them into old age.
The results of clinical trials conducted in Ethiopia by the Drugs for Neglected Diseases initiative (DNDi), in partnership with Médecins Sans Frontières (MSF), the University of Gondar, and Addis Ababa University, open the way for more effective and safer treatments for people with both HIV and visceral leishmaniasis (VL), a group of patients who have historically suffered from poor treatment options. The results were published today in PLOS Neglected Tropical Diseases.
Researchers have developed an intelligent system for 'tuning' powered prosthetic knees, allowing patients to walk comfortably with the prosthetic device in minutes, rather than the hours necessary if the device is tuned by a trained clinical practitioner. The system is the first to rely solely on reinforcement learning to tune the robotic prosthesis.
A survey of 20 disadvantaged neighborhoods across the North West (UK) has revealed the social influences on why people attend their local Accident & Emergency department.
New research published in The Lancet Neurology journal suggests that frailty makes older adults more susceptible to Alzheimer's dementia, and moderates the effects of dementia-related brain changes on dementia symptoms. The findings suggest that frailty should be considered in clinical care and management of Alzheimer's dementia.
African-Americans who experienced moderate to high financial stress had an increased risk of developing heart disease compared to those who did not report such stress, according to a longitudinal study performed by researchers from Brigham and Women's Hospital.
Defects in the transport of cells' energy organelles are a suspected cause of diseases including Alzheimer's, ALS, Huntington's and Parkinson's. A new study reveals the genetics behind mitochondrial shifts.