New license-free tools will allow researchers to estimate the size of DNA fragments for a fraction of the cost of currently available methods. The tools, called a DNA ladders, can gauge DNA fragments ranging from about 50 to 5,000 base pairs in length.
Swiss scientists from the University of Geneva, Switzerland, and the University of Basel have created artificial viruses that can be used to target cancer. These designer viruses alert the immune system and cause it to send killer cells to help fight the tumor. The results, published in the journal Nature Communications, provide a basis for innovative cancer treatments.
Researchers have discovered a biochemical signaling process that causes densely packed cancer cells to break away from a tumor and spread the disease elsewhere in the body.
George Washington University researchers, published in the New England Journal of Medicine, find through looking at genetic data sets of presumed cancer-free women who carry BRCA 1/2 variants, the co-occurrence of a rare COMT genetic variant in some women. This research outlines a strategy for looking at large genetic data sets for clues as to why a genetic carrier may never develop the associated diseases.
Researchers from MIT's Tangible Media Group have concocted something akin to edible origami, in the form of flat sheets of gelatin and starch that, when submerged in water, instantly sprout into three-dimensional structures, including common pasta shapes such as macaroni and rotini.
The Ben-Gurion U. researcher successfully redesigned a portion of MabThera, an FDA-approved drug used to treat certain autoimmune diseases and types of cancer, into a new molecule to treat ALS. 'Our experimental results on ALS transgenic mice showed a significant increase in life expectancy,' says Dr. Lichtenstein. 'Since the drug is already approved, we believe that we will only need limited preclinical testing to reach the clinical phase earlier than other initiatives.'
UW synthetic biology researchers have demonstrated a new method for digital information processing in living cells, analogous to the logic gates used in electric circuits. The circuits are the largest ever published to date in eurkaryotic cells and a key step in harnessing the potential of cells as living computers that can respond to disease, efficiently produce biofuels or develop plant-based chemicals.
Researchers have developed a new device to map the brain during surgery and distinguish between healthy and diseased tissues. The device provides higher resolution neural readings than existing tools used in the clinic and could enable doctors to perform safer, more precise brain surgeries.
Researchers at Oregon State University have developed two new modified toy car designs for children with disabilities in an effort to encourage them to further explore, play, and engage in physical and social activities.
A research team from the Department of Energy's Oak Ridge National Laboratory has performed the first-ever direct nanoscale examination of a living cell membrane. In doing so, it also resolved a long-standing debate by identifying tiny groupings of lipid molecules that are likely key to the cell's functioning.