UC San Diego study supports launch of Phase I clinical trial to test a designer DNA agent -- an antisense oligonucleotide that targets a gene called IRF4 -- in patients with multiple myeloma.
Dr. Claude Brodski, M.D., head of the BGU's Laboratory for Molecular Neuroscience, discovered that BMP5/7 signaling in neurons was significantly reduced in dopamine-producing brain cells, which could contribute to Parkinson's disease advancement.
Researchers at the National Institutes of Health (NIH) have discovered a new genetic disorder characterized by developmental delays and malformations of the brain, heart, and facial features.
Gene editing therapies, including CRISPR-Cas systems, offer the potential to correct mutations causing inherited retinal degenerations, a leading cause of blindness. Technological advances in gene editing, continuing safety concerns, and strategies to overcome these challenges
Researchers captured and comparted hi-res images of ribosome structures from sensitive and resistant bacteria and report that a water molecule needed for antibiotic binding was not present in the ribosomes from the drug-resistant bugs.
Until recently, oligodendrocytes were primarily thought to be a kind of cellular insulating tape that accelerates the transmission of electrical signals in the brain. A study by the University of Bonn (Germany) now shows that they are also important for the energy supply of neurons in some brain regions. The findings are published in the journal Cell Reports.
Study finds NAD+ break down leads to multi organ scarring, providing now a previously undiscovered pathogenic role of the enzyme CD38 in disease scarring.
Researchers at Canada's McMaster University have developed a new form of cultivated meat using a method that promises more natural flavour and texture than other alternatives to traditional meat from animals.
Histamine is a dangerous compound that occurs in spoiled food, such as mackerel, left at room temperature for too long. Unfortunately, existing histamine detection methods are inconvenient and expensive. To tackle this issue, a team of scientists from Chung-Ang University, Korea, has developed a novel histamine quantification strategy based on fluorescent carbon nanoparticles and histamine-binding peptides. Their approach is simple and inexpensive and allows one to efficiently assess food safety.
A test developed by Berkeley Lab scientists can quickly and easily detect whether sperm cells are carrying chromosomal defects, an advance that will help men who have undergone cancer treatment father healthy children.