Light beamed into a patient's blood through an optical fiber can determine whether blood is clotting during an operation, continuously and in real time. Researchers believe it could take the place of traditional blood tests in some situations and have myriad healthcare applications.
New light on a key factor involved in diseases such as Parkinson's disease, gastric cancer and melanoma has been cast through latest University of Otago, New Zealand, research carried out in collaboration with Australian scientists.
A Colorado State University team of single-molecule biophysicists and biochemists have shed light on a long-obscured cellular process: a mammalian cell membrane's relationship with a scaffolding underneath it, the cortical actin cytoskeleton. For the first time, the CSU team has made real-time observations of this cytoskeleton acting as a barrier that organizes proteins on the cell's surface, effectively playing traffic cop on the cell's membrane activities.
The mystery of what controls the range of developmental clocks in mammals -- from 22 months for an elephant to 12 days for a opossum -- may lie in the strict time-keeping of pluripotent stem cells for each unique species.
Researchers have designed a 3-D-printed porous scaffold for use in reconstructing ruptured anterior cruciate ligaments (ACL) in the knee and engineered it to deliver a human bone-promoting protein over an extended period of time to improve bone regeneration.
When many genes regulate a single trait, they commonly work together in large clusters or 'networks.' Taking this into account allows better predictions of how an individual's genetic make-up affects the trait concerned. The risk of perceiving the importance of an individual gene incorrectly is also reduced. This has been shown by researchers at Uppsala University, through a detailed analysis of thousands of related yeast cells.
Scientists at Rutgers and other universities have created a new way to identify the state and fate of stem cells earlier than previously possible. Understanding a stem cell's fate -- the type of cell it will eventually become -- and how far along it is in the process of development can help scientists better manipulate cells for stem cell therapy.
Sometimes cells spit out things we don't want them to -- like medications. Researchers have determined the three-dimensional structure of a tiny pump that expels, among other things, chemotherapy agents. This new knowledge could lead to the design of more effective drugs.
An international team of researchers, funded by Morris Animal Foundation, has shown that adipose (fat) stem cells might be the preferred stem cell type for use in canine therapeutic applications, including orthopedic diseases and injury.
Successful results of a University of Liverpool-led trial that utilised nanotechnology to improve drug therapies for HIV patients has been presented at the Conference on Retroviruses and Opportunistic Infections (CROI) in Seattle, a leading annual conference of HIV research, clinical practice and progress.