An interdisciplinary research study of the University of Barcelona identified two potential candidates to treat Alzheimer's disease. These are two marine molecules, meridianine and lignarenone B, able to alter the activity of GSK3B activity, a protein associated with several neurodegenerative diseases.
A study performed by researchers at the Institute for Advanced Chemistry of Catalonia (IQAC-CSIC) from the Spanish National Research Council (CSIC) pioneers the use of whole living cells (human lung adenocarcinoma) in dynamic combinatorial chemistry systems. This research, published in the journal Angewandte Chemie International Edition, proposes a new methodology to discover new bioactive molecules in a realistic biological medium. This methodology could help in the future to develop methods to differentiate healthy versus cancer cells, or to protect the extracellular matrix against pathogens.
More than a quarter century after the Gulf War, female veterans who saw combat have nearly a twofold risk of reporting more than 20 total medical symptoms, like cognition and respiratory troubles, than their fellow female veterans who were not deployed, investigators report.
Japanese researchers have succeeded in catalytic asymmetric iodoesterification from simple alkene substrates and carboxylic acids. Published in Angewandte Chemie International Edition on April 27, this new research, was accomplished by precisely controlling multiple interactions in a single catalytic reaction. This synthetic reaction is expected to contribute to the simplification of industrial processes and greater efficiency in optical active drug production.
NIST Scientists used UV light and glow powder to study the way small amounts of drug residue get spread around a forensic chemistry lab when analysts test seized drugs. Their study, recently published in Forensic Chemistry, addresses safety concerns in an age of super-potent synthetic drugs like fentanyl, which can potentially be hazardous to chemists who handle them frequently.
A technology to further accelerate the commercialization of Colloidal Quantum Dot(CQD) Photovoltaic(PV) devices, which are expected to be next-generation photovoltaic devices, has been developed.
In a Science Policy Forum, lead author Sam Weiss Evans joins more than a dozen biosecurity practitioners and analysts in calling for a new approach to biosecurity governance, grounded in experimentation. Developing an ability to rethink and test assumptions about biology, security, and society is vital to evolving biosecurity for the 21st Century. This means being systematic in governance design, periodically reassessing based on lived experience, and learning across biosecurity environments.
Did coronavirus mutate from a virus already prevalent in humans or animals or did it originate in a laboratory? As scientists grapple with understanding the source of this rapidly spreading virus, the Grunow-Finke assessment tool (GFT) may assist them with determining whether the coronavirus outbreak is of natural or unnatural origins.
Depending on whether uranium is released by the civil nuclear industry or as fallout from nuclear weapon tests, the ratio of the two anthropogenic, i.e. man-made, uranium isotopes 233U and 236U varies. These results were lately found by an international team at the University of Vienna and provides a promising new "fingerprint" for the identification of radioactive emission sources. As a consequence, it is also an excellent environmental tracer for ocean currents.
ORNL Story Tips: Antidote chasing, traffic control and automatic modeling