A new study summarizes over 30 years of clinical experience in the treatment and management of glutaric acidemia type 1 (GA1), a rare and potentially devastating metabolic disorder caused by variants in the GCDH gene. The study followed the clinical course of 168 individuals with GA1 who were born between 1973 and 2019 and originated from 26 states and 6 countries.
Researchers from the Masonic Medical Research Institute (MMRI), the Precision Cardiology Lab (PCL) of the Broad Institute at MIT and Harvard, Bayer USA, Massachusetts General Hospital, and University of Pennsylvania collaborated to uncover some pressing questions about the biology of the heart. While understanding the mechanisms causal to human heart disease remain active areas of research for many scientists, important knowledge gaps about its composition and function remain unknown.
While there is little doubt that COVID-19 will have lasting impacts on health and the economy, a group of researchers is bringing attention to the effects the pandemic could have on the careers of scientific researchers. Carnegie Mellon University and Max Planck Institute physicist Ulrike Endesfelder, University of Stuttgart's Dirk Pflüger and Technische Universität Braunschweig's Timo de Wolff launched a Twitter campaign #StopPandemicBias, which aims to bring broader understanding to how COVID-19 will impact scientists
Amid growing criticism of the traditional "publish or perish" system for rewarding academic research, an international team has developed five principles that institutions can follow to measure and reward research integrity. Publishing on July 16, 2020 in the open access journal PLOS Biology, the team believes that applying these principles in academic hiring and promotion will enhance scientific integrity and amplify the benefits of research to society.
The COVID-19 pandemic is having a disproportionate, negative impact on the careers of scientists with young children at home, a new survey finds. They have been forced to drastically reduce the amount of time they spend on their research, which could have long-term effects on their careers and could exacerbate existing inequalities.
Researchers affiliated with the Robert Graham Center for Policy Studies in Family Medicine and Primary Care conducted a descriptive bibliometric analysis to determine the gender ratio of scholarly authorship on publications by its researchers between 2008 and 2018.
A recent study, affiliated with South Korea's Ulsan National Institute of Science and Technology (UNIST) has unveiled a novel material that could enable major leaps in the miniaturization of electronic devices.
A SU2C 'Dream Team' co-funded by OCRAA and NOCC presented results at ASCO of "MAGENTA", the first large randomized clinical trial aimed at making genetic testing for cancer risk more accessible. Nearly 4000 participants used an at home spit-test and was randomly assigned to 4 arms, demonstrating genetic testing can be provided remotely and pre- and post-test genetic counseling can be skipped without causing increased distress to patients undergoing genetic testing from their home.
Stand Up To Cancer®-supported research will be presented will be presented during the American Association for Cancer Research Annual (AACR) Virtual Meeting 1. Work presented by SU2C-funded investigators highlights continued support for developing effective immunotherapy approaches to pediatric and young adult ALL and lung cancer and progress in the emerging field of Cancer Interception, seeking approaches to intervene and stop the formation or progression of early or pre-cancerous conditions.
A new study looked at more than 1,300 retail banking sales teams in a large regional bank to explore whether groups vary in how they convert resources into performance. The study found that resources are generally helpful, but groups differ in the results they achieve. The variation is also largely associated with the group's coordinated attention - specifically, their patterns of email communication. The findings have implications for how firms can operate more efficiently.