Improved compensation, expanded mentorship and training opportunities, and concrete measures to improve workforce diversity are all needed to address attrition from the ranks of physician scientists specializing in infectious diseases, and to ensure that the next generation of that work force is sufficient to bring quests for new life-saving treatments and cures to fruition, according to recommendations released today by IDSA, HIVMA and PIDS.
A new comprehensive natural history study about Amish nemaline myopathy (ANM) in the Old Order Amish population focuses on the promise of gene therapy for this lethal disorder. Amish nemaline myopathy (ANM) is an infantile-onset muscle disease linked to a mutation of the TNNT1 gene. The study summarizes genealogical records, clinical data, and molecular reports of one hundred and six ANM patients born between 1923 and 2017 and was led by researchers from the Clinic for Special Children in Strasburg, Pa.
The conservation of lions, while also maintaining the well-being of people that live around them, is a complex problem that should be addressed by a wide-range of professionals working together. Rather than focusing solely on human-lion interaction, other factors such as the environment, wild prey and domesticated livestock need to be considered to get a full evaluation of the problem. This approach should help address the dramatic decrease in lion populations seen in recent years.
Academic societies may be able to increase gender equity through supporting female leadership and making an outward commitment of equality, according to a study published May 30, 2018 in the open-access journal PLOS ONE by Dominique Potvin from University of the Sunshine Coast, Hervey Bay, Australia and colleagues.
An international team of researchers, affiliated with South Korea's Ulsan National Institute of Science and Technology (UNIST) has discovered a novel method for the synthesis of ultrathin semiconductors.
ANU archaeologist Dr. Catherine Frieman unearths an intact 4,000-year-old human cremation in clay pottery urn on a Cornish site she discovered by accident.
A new study led by a UTSA researcher examines the social perceptions of Pre-Exposure Prophylaxis (PrEP), a medication to prevent HIV, among gay and bisexual men in Texas. Over a six-month period, UTSA assistant professor Phillip Schnarrs worked with education, health care and nonprofit partners to survey more than 100 gay and bisexual men from the White, Latino and African-American communities about their perceptions of PrEP.
A study analyzed the traditional model of education versus the flipped classroom model -- where pre-recorded lectures are viewed outside of the classroom and in-person class time is devoted to interactive exercises, discussions, and group projects. The results showed there were no statistically significant differences in test scores or students' assessments of the flipped classes. However, students reported that the flipped format allowed for greater flexibility.
A new, innovative approach to lung cancer treatment, administration of immunotherapy prior to surgery yielded encouraging outcomes in findings from SU2C-CRI Dream Team researchers. Two doses of anti-PD1 immunotherapy nivolumab several weeks prior to surgery was found to be safe; 45 percent of the trial patients showed little evidence of disease upon follow-up; and patients' immune systems intercepted circulating tumor cells to potentially prevent recurrence and metastasis, consistent with SU2C's research focus on Cancer Interception.
Preprints -- scientific manuscripts that are posted at a recognized online repository before peer review -- have the potential to speed up the reporting of scientific research in infectious disease outbreaks, argue Michael Johansson and colleagues in an Essay in PLOS Medicine.