Indium-gallium-zinc oxide ceramics are used as the backplane for flat-panel displays, this was made possible through substantial synergistic contributions coming from the powerhouse that is Japan. A team of researchers from Japan reports the synthesis of centimeter-scale single crystals of a particular type of these semiconductors, InGaZnO4 (IGZO-11), with attractive characteristics such as wide band gap and high electrical mobility and conductivity, which make it promising candidates for transparent optoelectronic devices like touchable displays and organic LEDs.
Interdisciplinarity is becoming increasingly important in research. Yet there are structures in place that make careers in science more difficult for interdisciplinary researchers, according to Ruth Müller, Professor of Science and Technology Policy at the Technical University of Munich (TUM). In this interview, she talks about her study on a research center in Sweden and about how existing hurdles could be overcome and interdisciplinary research could be promoted in more sustainable ways.
An analysis of US intelligence programs aimed at collaborating with academic and industry partners finds that these collaborations are valuable for addressing complex intelligence challenges. The study also notes that institutional silos, lack of information sharing and lack of trust are obstacles to getting the most out of these collaborative efforts.
SU2C supported researchers will present work on pediatric brain tumors, cfDNA for early cancer detection, dual blockade of CTLA-4 and PD-1 in mCRC, cancer interception of pancreatic and lung cancers, machine learning RECIST in RWE study of lung cancer, and molecular markers of response to neoadjuvant nivolumab in resectable NSCLC.
A team from the transdisciplinary laboratory FoAM Kernow and the British Science Association detail how to run an innovative approach to understanding evidence called AccessLab in a paper published on May 28 in the open-access journal PLOS Biology. The AccessLab project enables a broader range of people to access and use scientific research in their work and everyday lives.
Pancreatic Cancer Collective-funded research (Lustgarten Foundation and Stand Up To Cancer) from Dr. Tony Hunter (Salk Institute) and the SU2C-CRUK-Lustgarten Pancreatic Cancer Dream Team has found the presence of a key protein (Leukemia Inhibitory Factor or LIF) in PDAC microenvironment may be an exploitable treatment target to slow tumor progression or metastasis and may lead to the development of new targeted strategies for pancreatic cancer therapy.
Lustgarten Foundation and SU2C offer comments on research describing a new combination drug therapy demonstrating promise for patients with pancreatic cancer. This research is the foundation for a Pancreatic Cancer Collective New Therapies Challenge Grant to Dr. Martin McMahon (Huntsman Cancer Institute). The Collective offers this video of Dr. McMahon and David Tuveson, MD, PhD commenting.
Publish or perish is an adage with particular sting for women and other underrepresented scholars prone to not getting deserved credit on scientific papers. F&W scientists will provide perspective and pointers at the upcoming AAAS Annual Meeting.
An analysis of nearly 24,000 grant applications at the Canadian Institutes of Health Research finds that women are less successful in receiving funding if reviewers are explicitly asked to review the principal investigator, rather than when they are asked to assess the quality of the science. The study is published as part of a special issue of The Lancet on advancing women in science, medicine and global health.
Researchers have combined the largest description of ST3GAL5 (GM3 synthase) deficiency using detailed natural history data from 104 individuals of Amish ancestry born between 1986 and 2017 with a definite or probable diagnosis of ST3GAL5 deficiency. The study examined objective measures of biochemistry, auditory function, brain development, and caregiver burden. GM3 synthase is encoded by ST3GAL5, and is essential for synthesis of the most biologically relevant gangliosides in mammals.