A new study aims to provide healthy couples who have a child affected by a developmental disorder with a personalised pre-conception risk evaluation, in order to determine the likelihood of a future child being affected by the same condition.
Researchers from Dartmouth College, New Hampshire have found evidence that players born in the first quarter of the year are more likely to play in the National Football League.
In the first study of its kind, LSU Health New Orleans researchers report that women's pre-pregnancy overweight or obesity produces changes in breast milk, which can affect infant growth.
When scientists subjected two-toned pygmy squid and bigfin reef squid to CO2levels projected for the end of the century, they received some surprising results.
A team led by Professor Liu Changmei from the State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology of the Chinese Academy of Sciences, has shown that the PcG protein EED is essential for the proper formation of the DG.
The study of University of Jyväskylä and University of Vienna shows that voles are able to determine the difference between the smell of a predator, the smell of a non-stressed vole, and the smell of a vole who encountered a predator.
A team at Harvard's Wyss Institute has leveraged its microfluidic Organs-on-Chips technology in combination with a developmentally-inspired hypoxia-mimicking approach to differentiate human pluripotent stem (iPS) cells into brain microvascular endothelial cells (BMVECs). The resulting 'hypoxia-enhanced BBB Chip' recapitulates cellular organization, tight barrier functions and transport abilities of the human BBB; and it allows the transport of drugs and therapeutic antibodies in a way that more closely mimics transport across the BBB in vivo than existing in vitro systems.
Scientists at Tokyo Tech, Yamagata University and Harvard University have discovered that environmental oxygen plays an important role shaping the hands and feet during development. They found that removal of the interdigital membrane by cell death depends on the production of reactive oxygen species, which only occurs in embryos exposed to a high oxygen concentration. This work gives an interesting example of how novel strategies to shape the body parts may appear during development.
Free fingers have many obvious advantages on land, such as in locomotion and grasping, while webbed fingers are typical of aquatic or gliding animals. But both amphibians and amniotes -- which include mammals, reptiles, and birds -- can have webbed digits. In new research from Japan, scientists show that during embryo development, some animal species detect the presence of atmospheric oxygen, which triggers removal of interdigital webbing. Their research appears June 13, 2019 in the journal Developmental Cell.
Mutations in the gene that codes for SLIT2, a protein expressed in fetal cells in placentas and involved in directing the growth of the fetal nervous system, may contribute to premature births, possibly by activating the mother's immune system. Mika Rämet of the University of Oulu and colleagues report these findings in a new study published June 13 in PLOS Genetics.