New license-free tools will allow researchers to estimate the size of DNA fragments for a fraction of the cost of currently available methods. The tools, called a DNA ladders, can gauge DNA fragments ranging from about 50 to 5,000 base pairs in length.
Changing natural electrical signaling in non-neural cells improves innate immune response to bacterial infections and injury. Tadpoles that received therapeutics, including those used in humans for other purposes, which depolarized their cells had higher survival rates when infected with E. coli than controls. The research has applications for treatment of emerging diseases and traumatic injury in humans.
Experiments with tiny, shelled organisms in the ocean suggest big changes to the global carbon cycle are underway, according to a study from the University of California, Davis.
The research findings imply that patients with genitourinary birth defects due to 22q11.2 changes in gene dosage should also be evaluated for other potential birth defects seen in patients with DiGeorge syndrome that would affect the patient's future health.
A recent study from UBC's Okanagan campus identifies new genetic markers in sockeye salmon that can help improve management of fish populations.
A team of researchers, led by a UC Riverside plant cell biologist, has for the first time identified a small RNA species and its target gene that together regulate female germline formation in plants -- crucial knowledge for manipulating plant reproduction in order to improve agriculture. The new work not only identifies a regulatory module for an important developmental process, it also implies that there is likely cell-to-cell communications via RNA or protein in this process.
Zika virus infection passes efficiently from a pregnant monkey to its fetus, spreading inflammatory damage throughout the tissues that support the fetus and the fetus's developing nervous system, and suggesting a wider threat in human pregnancies than generally appreciated, University of Wisconsin-Madison researchers have found.
Scientists at the University of Kent, working with colleagues from the genetics research industry, have developed a new genetic screening device and protocol that helps pig breeding. Through her work, Dr. Rebecca O'Connor in the School of Biosciences, found previously undiscovered, fundamental flaws in the pig genome, the results of which have contributed to improved mapping of the pig genome.
Edible dormice feed preferably on high-energy seeds for reproduction and putting on fat reserves. Beech trees, however, save energy by producing seeds only in certain years on a large scale. A long-term study by researchers from Vetmeduni Vienna has shown for the first time that edible dormice avoid areas with a high beech density. They prefer areas with a mix of conifers and beech trees and thus a balanced food supply.
Researchers from the University of Basel in Switzerland have identified a key regulator gene for the formation of cardiac valves -- a process crucial to normal embryonic heart development. These results are published in the journal Cell Reports today.