Enzyme cycling is a sensitive assay method that exploits amplification techniques. We recently developed a novel enzymatic cycling method, which utilizes both the forward and reverse reactions of creatine kinase (CK), for the quantitative determination of creatine.
A Syracuse University engineering team has developed a process that combines biomaterials-based cell patterning and stem cell technology to make a 3-D tissue model that could mimic early stage human heart development. Embryotoxicity is just one potential use of the modeling platform.
US Army-funded researchers at Brandeis University have discovered a process for engineering next-generation soft materials with embedded chemical networks that mimic the behavior of neural tissue. The breakthrough material may lead to autonomous soft robotics, dual sensors and actuators for soft exoskeletons, or artificial skins.
The International Journal of Cancer has just published the results of an experimental therapy tested on mice. The research, led by the Signaling Lab research group of the UPV/EHU's Faculty of Medicine and Pharmacy and the Department of Pharmacology, Pharmacy and Pharmaceutical Technology of the University of Santiago de Compostela, achieved an 80 percent reduction in liver metastasis brought about by colon cancer.
A cheap, safe and effective method of dealing with harmful algal blooms is on the verge of being introduced following successful field and lab tests.
Researchers at the University of Washington and the Allen Institute for Brain Science have developed a new method to classify and track the multitude of cells in a tissue sample. In a paper published March 15 in the journal Science, the team reports that this new approach -- known as SPLiT-seq -- reliably tracks gene activity in a tissue down to the level of single cells.
Chinese scientists and clinicians have developed a learning artificial intelligence system which can diagnose and identify cancerous prostate samples as accurately as any pathologist. This holds out the possibility of streamlining and eliminating variation in the process of cancer diagnosis. It may also help overcome any local shortage of trained pathologists. In the longer term it may lead to automated or partially automated prostate cancer diagnosis.
Fungi may be harmful pathogens. On the other hand, they are used for the production of food or medicine and in bioengineering. In either case, it is required to precisely understand their growth mechanism. Researchers of Karlsruhe Institute of Technology (KIT) have made a big step forwards: Using high-performance light microscopy, they watched mold fungi as they grew in the cell. The findings are presented in Science Advances.
Researchers from the Department of Molecular Biology and Genetics and from the Department of Biomedicine at Aarhus University have collaboratively developed and described a llama-antibody that might have significant impact for future diagnostics and treatment of, e.g., kidney diseases.
UCLA scientists have developed a new method that utilizes microscopic splinter-like structures called 'nanospears' for the targeted delivery of biomolecules such as genes straight to patient cells.