The August edition of SLAS Technology features the cover article, 'Technologies for the Directed Evolution of Cell Therapies,' a review featured in the journal's March 2019 edition. The research, led by Dino Di Carlo, Ph.D., (University of California Los Angeles) highlights how the next generation of therapies are moving beyond the use of small molecules and proteins to using whole cells.
A new study using a special type of electron microscope using samples cooled to extremely cold temperatures provides critical information for drug developers seeking to reduce nausea and vomiting side effects of cancer treatments. Published in Nature Communications, the study offers a glimpse into how widely used anti-nausea drugs attach to their target protein in the gastrointestinal tract.
Virginia Tech researcher Clément Vinauger has discovered new neurobiology associated with mosquito vision and sense of smell that explains how Aedes aegypti mosquitoes track their victims.
The recent study from Burst Biologics challenges existing standards and outlines future safety and potency benchmarks.
A team of scientists led by Oak Ridge National Laboratory have discovered the specific gene that controls an important symbiotic relationship between plants and soil fungi, and successfully facilitated the symbiosis in a plant that typically resists it.
A team led by Kyoto University physicists and Kyoto Prefectural University of Medicine (KPUM) ophthalmologists, developed a 'quantitative biomarker' that makes it possible to assess the quality of corneal cells -- and even predict their long-term efficacy -- through simple observation.
A team led by JGI scientists has overhauled the perception of inovirus diversity. Using machine learning, they identified more than 10,000 inovirus-like sequences compared to the 56 previously known genomes of these filamentous viruses. The results revealed inoviruses are in every major microbial habitat -- including soil, water, and humans -- around the world.
Using single-molecule imaging, researchers witness how molecules find and fix damaged DNA.
Several brain circuits that identify emotions are solidified early in development and include diverse regions beyond the amygdala, according to new research in children, adolescents, and young adults published in JNeurosci.
Researchers in the group of Jan Michiels (VIB-KU Leuven Center for Microbiology) identified a mechanism of how sleepy bacteria wake up. This finding is important, as sleepy cells are often responsible for the stubbornness of chronic infections. Findings published in Molecular Cell reveal new perspectives on how to treat chronic infections, for example by forcing bacteria to wake up.