Researchers at Leipzig University and the German Centre for Integrative Biodiversity Research (iDiv) have compiled the world's most comprehensive list of known plant species. It contains 1,315,562 names of vascular plants, thus extending the number by some 70,000 - equivalent to about 20%. The researchers have also succeeded in clarifying 181,000 hitherto unclear species names. The data set has now been published in Scientific Data. This marks the culmination of ten years of intensive research work.
Wheat researchers at the John Innes Centre are pioneering a new technique that promises to improve gene discovery for the globally important crop.
With new insights into how the genetic tool CRISPR - which allows direct editing of our genes - evolved and adapted, we are now one step closer to understanding the basis of the constant struggle for survival that takes place in nature. The results can be used in future biotechnologies.
A computational model of a human lung cell has been used to understand how SARS-CoV-2 draws on human host cell metabolism to reproduce by researchers at the University of Warwick. This study helps understand how the virus uses the host to survive, and enable drug predictions for treating the virus to be made.
Bread wheat can grow in highly diverse regional environments. An important reason for its great genetic variety is the cross-hybridization with many chromosome fragments from wild grasses. This is shown by the genome sequences of 10 wheat varieties from four continents, which an international consortium including researchers from the University of Zurich has now decoded.
Nanoparticles are promising drug delivery tools but they struggle to get past the immune system's first line of defense: proteins in the blood serum that tag potential invaders. Now, Harvard researchers have developed an ionic forcefield that prevents proteins from binding to and tagging nanoparticles. In mouse experiments, nanoparticles coated with the ionic liquid survived significantly longer in the body than uncoated particles.
In a landmark discovery for global wheat production, a University of Saskatchewan-led international team has sequenced the genomes for 15 wheat varieties representing breeding programs around the world, enabling scientists and breeders to much more quickly identify influential genes for improved yield, pest resistance and other important crop traits.
Multimaterial fibers that integrate metal, glass and semiconductors could be useful for applications such as biomedicine, smart textiles and robotics. But because the fibers are composed of the same materials along their lengths, it is difficult to position functional elements, such as electrodes or sensors, at specific locations. Now, researchers reporting in ACS Central Science have developed a method to pattern hundreds-of-meters-long multimaterial fibers with embedded functional elements.
In a recent study published in Stem Cell Reports, Seba Almedawar, PhD, and colleagues with the Center for Regenerative Therapies TU Dresden, Germany, used induced pluripotent stem cells (iPSCs) derived from the skin of healthy donors and of patients with retinitis pigmentosa to find drugs with the potential to enhance RPE phagocytosis.
Recently, National Institutes of Health researchers used a variety of advanced drug screening techniques to test out more than 10,000 compounds in search of a cure. To their surprise, they found that the widely used antibiotic methacycline was effective at preventing brain infections and reducing neurological problems associated with the virus in mice.