In December, the Nobel Prize for Medicine and Physiology will be awarded for the identification of genes that control the inner clock. The honored academics examined fruit flies to determine the biorhythm. Biochemist Professor Dr. Dorothee Staiger of Bielefeld University has been researching the inner clock of plants for 20 years. Her team has now published a new study in the research journal Genome Biology.
The Association for Molecular Pathology, the premier global, non-profit molecular diagnostics professional society, today published 17 consensus recommendations to help clinical laboratory professionals achieve high-quality sequencing results and deliver better patient care. The report, 'Standards and Guidelines for Validating Next Generation Sequencing Bioinformatics Pipelines: A Joint Recommendation of the Association for Molecular Pathology and College of American Pathologists,' was released online ahead of publication in The Journal of Molecular Diagnostics.
Researchers in physics and mathematics have long used 'preprints' -- preliminary versions of their scientific findings published on internet servers for anyone to read. In 2013, similar services were launched for biology, but following a chance discovery, Matthew Cobb, a scientist and historian at the University of Manchester, has unearthed a long-forgotten experiment in biology preprints that took place in the 1960s. He has written about them in a study publishing Nov. 16 in the open-access journal PLOS Biology.
Machine learning could improve our ability to determine whether a new drug works in the brain, potentially enabling researchers to detect drug effects that would be missed entirely by conventional statistical tests, finds a new UCL study published in Brain.
A new study sheds light on connections between birth month and risk for certain diseases.
Professor Hattori and Professor Kenya Honda of Keio University School of Medicine led research to investigate the relationship between salivary microbes and IBD, and they found that when the bacterium Klebsiella pneumoniae colonizes in an intestine out of microbial balance, immune cells called T helper 1 (TH1) become overactive in the gut, resulting in intestinal inflammation leading to the onset of IBD.
Lobachevsky University scientists under the supervision of Alexey Mikhailov, Head of the UNN PTRI Laboratory of Thin Film Physics and Technology, are working to develop an adaptive neural interface that combines, on the one hand, a living culture, and on the other, a neural network based on memristors. This project is one if the first attempts to combine living biological culture with a bio-like neural network based on memristors.
In an article published in Nature Communications, researchers at the University of California, Riverside and the University of Pennsylvania School of Medicine used high-powered microscopy and rheometry -- the measurement of how materials become deformed in response to applied force -- to view the blood clotting process in real time and at the cellular level. The findings will be useful in the development of new therapies for clotting disorders.
Researchers from ITMO University and Center of Physical and Chemical Medicine developed an algorithm capable of tracking the spread of antibiotic resistance genes in gut microbiota DNA and revealed additional evidence of resistance genes transfer between different bacterial species. The method can not only contribute to the development of effective therapy schemes, but also curb the spread of superbugs. The results of the research were published in 'Bioinformatics' journal.
Researchers have reported an approach to photoacoustic imaging that offers vastly improved resolution, setting the stage for detailed in vivo imaging of deep tissue.