Using a bioinformatics approach, University of California San Diego School of Medicine researchers found that CD4+ T cell's binding partner, a molecule called MHC-II, may have even more influence on emerging tumors than MHC-I, the better known partner of CD8+ T cells. The finding, published September 20 in Cell, may help researchers improve cancer immunotherapies and predict which patients will respond best.
Sample size (the number of individuals examined for a study) is the most important factor determining the accuracy of the study results.
A new study is challenging the long-held belief that specialization in mammal backbones date back to the earliest land animals. Evidence suggests that the spine gained regions during mammal evolution, with the first -- located in close proximity to the shoulders and front legs -- appearing some 250 million years ago, just as dramatic changes began to appear in the forelimbs of animals known as non-mammalian therapsids.
Scientists at the Centre for Genomic Regulation in Barcelona, Spain, have uncovered the role of special chemical 'tags' in controlling vital genes involved in early mammalian development, publishing their findings in the journal Nature Genetics.
A team at Princeton's Lewis-Sigler Institute for Integrative Genomics has produced new resources for research involving the roundworm C. elegans: a comprehensive view of which genes are active in each of the four major tissues of adult worms, as well as a tool for predicting gene activity across 76 more specific cell types.
University of Oregon chemists have created a new class of fluorescent dyes that function in water and emit colors based solely on the diameter of circular nanotubes made of carbon and hydrogen.
An international team of researchers has outlined a plan for how to measure changes in key traits of animals and plants and provide these data to policymakers to improve natural resource management and keep nations on track to meet global biodiversity and sustainability goals.
New clinical and molecular evidence shows sperm quality and reproductive outcomes are improved when semen is provided after just 1-3 hours of abstinence.
Scientists from EPFL and the University of Geneva have discovered a 'code' of architect genes that are expressed in specific combinations during the development of hands and fingers. The study decrypts developmental gene expression at the level of the single cell in developing limbs and expands our understanding of the genetics behind growing limbs.
UCSB researchers use environmental DNA to detect the presence of white sharks in local waters.