Researchers at Insilico Medicine , AgeX Therapeutics and the Biogerontology Research Foundation have published a landmark study titled 'Use of deep neural network ensembles to identify embryonic-fetal transition markers: repression of COX7A1 in embryonic and cancer cells' in the journal Oncotarget.
Aspergillus fungi are pathogens, decomposers, and important sources of biotechnologically-important enzymes. In the Proceedings of the National Academy of Sciences, a team led by researchers at the Technical University of Denmark, the DOE Joint Genome Institute and the Joint BioEnergy Institute report the first outcome from the large-scale sequencing of 300+ Aspergillus species. These findings are a proof of concept of novel methods to functionally annotate genomes to more quickly identify genes of interest.
What do 3,044 golden retrievers across the nation have in common? They are the principal players in the second published scientific paper from Morris Animal Foundation's groundbreaking Golden Retriever Lifetime Study, highlighting characteristics of the dogs in this landmark study including age, medical condition, preventive care and more.
Some animals, such as geckos, can easily climb up walls and across ceilings. But currently, no material exists that allows everyday people to scale walls or transverse ceilings as effortlessly. Now, scientists report in ACS Applied Materials and Interfaces a dry adhesive that could someday make it easier to defy gravity.
In Germany, non-technical summaries of all authorized projects involving animals are published in the database AnimalTestInfo, which is operated by the German Federal Institute for Risk Assessment and is at present unique worldwide. Using this searchable and transparent database, the general public can easily find information about animal tests.
In a major pan-European study, a research team from Germany have successfully extracted environmental DNA from as many as 218 lakes to refute a long-year belief that vital microorganisms do not differ significantly between freshwater bodies and geographic regions the way plants and animals do. Their new-age approach to biodiversity studies resulted in the largest freshwater dataset along with a study published in the open access journal Metabarcoding and Metagenomics.
Missouri Botanical Garden researchers used DNA testing to rediscover Dracaena umbraculifera, which was thought to be extinct. The methods and results were published in Oryx. The authors include Garden researchers in both St. Louis and Madagascar.
Plant biomass contains considerable calorific value but most of it makes up robust cell walls, an unappetizing evolutionary advantage that helped grasses to survive foragers and prosper for more than 60 million years. The trouble is that this robustness still makes them less digestible in the rumen of cows and sheep and difficult to process in bioenergy refineries for ethanol fuel. Until now, with the discovery of a gene that controls that robustness.
The Eveland laboratory's research findings, 'Brassinosteroids modulate meristem fate and differentiation of unique inflorescence morphology in Setaria viridis', were recently published in the journal The Plant Cell.
A research team at SISSA, led by Professor Giovanni Bussi, has developed a computerised simulation model which can effectively predict the three-dimensional conformation of the RNA filament starting from a sequence of nucleotides. The work, just published in Nucleic Acids Research, promises to have a significant impact in the research and application field.