Today in Nature Communications, researchers from BTI and the Shanghai Normal University report a new draft genome of Spinacia oleracea, better known as spinach. Additionally, the authors have sequenced the transcriptomes (all the RNA) of 120 cultivated and wild spinach plants, which has allowed them to identify which genetic changes have occurred due to domestication.
A new study by an international group of scientists reveals that the Zika virus outbreak in Florida wasn't a single virus introduction but rather at least four separate introductions from the Caribbean and Central America that each led to local chains of transmission.
A team of scientists have traced the evolution of whale size through more than 30 million years of history and found that very large whales appeared along several branches of the family tree about 2 to 3 million years ago. Increasing ice sheets in the Northern Hemisphere during this period likely altered the way whales' food was distributed in the oceans and enhanced the benefits of a large body size, the scientists say.
The most common type of malignant childhood brain cancer has been identified as seven separate conditions each needing a different treatment, new research has revealed.
Much of what we thought we knew about the human papilloma virus (HPV) in HPV-related head and neck cancers may be wrong, according to a newly published study by Virginia Commonwealth University (VCU) researchers that analyzed data from The Human Cancer Genome Atlas. Head and neck cancers involving HPV are on the rise, and many experts believe we are seeing the start of an epidemic that will only get worse in the coming years.
After decades of research aiming to understand how DNA is organized in human cells, scientists at the Gladstone Institutes have shed new light on this mysterious field by discovering how a key protein helps control gene organization.
Scientists at Princeton University have developed a new algorithm to track neurons in the brain of the worm Caenorhabditis elegans while it crawls. The algorithm, presented in PLOS Computational Biology by Jeffrey Nguyen and colleagues, could save hundreds of hours of manual labor in studies of animal behavior.
Immunotherapy supercharges the body's own disease-fighting mechanisms to combat cancer. Researchers are using advanced computing resources at TACC to simulate the effects of immunotherapy drugs, develop novel dose-finding designs for clinical trials, and analyze and share next-generation immune protein sequence data. These efforts are helping scientists determine which immune treatments may be most effective for which patients and allowing them to design new and improved immunotherapies.
Debate exists over how life began on Earth, but a new study provides evidence for a 'metabolism-first' model. Scientists at the University of Illinois mined the Gene Ontology database to trace the origins and evolution of molecular functions through time. The study shows metabolism and binding arose first, followed by the functional activities of larger macromolecules and cellular machinery.
Scientists carried out a research aimed at identifying the genes and mutations in them that allow mycobacteria to thrive in people with altered immune status including HIV-positive patients. They developed a catalog of mutations in more than 300 virulence (disease causing) genes. Further analysis identified a set of three mutations which may enable mycobacteria to develop rapidly in an immunocompromised environment.