An experimental vaccine developed in Europe to prevent infection by Crimean-Congo hemorrhagic fever virus (CCHFV) has protected cynomolgus macaques in a new collaborative study from National Institutes of Health scientists. The study, published in Nature Microbiology, comes about three years after the same research group developed the macaque model for CCHFV. No specific treatments or vaccines for CCHFV exist.
Each year, hundreds of thousands of people lose their mobility or life after having been bitten by a venomous snake. The problem is particularly widespread in low-income countries, as antivenom is expensive, or not available, and treatment requires trained healthcare personnel. Now Danish researchers propose an alternative type of antivenom, named Serpentides, that is simple to make, cheaper to produce and can be used by anyone, anywhere.
Fiji's national vaccine program against pneumonia, a serious lung condition, and rotavirus, a common disease which causes severe diarrhoea and vomiting, has reduced illness and death, new research shows.
Recently, National Institutes of Health researchers used a variety of advanced drug screening techniques to test out more than 10,000 compounds in search of a cure. To their surprise, they found that the widely used antibiotic methacycline was effective at preventing brain infections and reducing neurological problems associated with the virus in mice.
A team from the Institut national de la recherche scientifique (INRS) has demonstrated the effectiveness of an inexpensive molecule to fight antibiotic-resistant strains of the bacteria responsible for gonorrhea and meningococcal meningitis. These two infections affect millions of people worldwide. The results of this research, led by Professor Frédéric Veyrier and Professor Annie Castonguay, have just been published online in the Antimicrobial Agents and Chemotherapy journal.
Engineers reveal how zinc oxide nanoneedles and droplet hydrodynamics can stop pathogens.
Use of an algorithm for computing viral mutations homogeneously across sources, using cloud computing.
When it comes to curbing the spread of COVID-19, test frequency and test turnaround-time are far more important than test sensitivity, according to a new study published in the journal Science Advances. The authors say frequent, rapid tests make "personalized stay-at-home orders" possible.
Using intercellular calcium waves, rotavirus amplifies its ability to cause disease beyond the cells it directly infects. This is the first virus identified to activate ADP-mediated intercellular calcium waves.
By experimentally comparing wild populations of Ae. aegypti the researchers discovered that the invasive subspecies is very effective at transmitting the Zika virus not only because it has more frequent contacts with humans for blood meals, but also as a result of its greater susceptibility to the virus relative to the African subspecies.