A Norwegian biotech company called Phoenix Solutions AS is working with the Translational Genomics Research Institute (TGen), a Phoenix, Arizona-based biomedical research facility, to test the use of these pulsed sound waves to direct and focus cancer drug therapies.
Saint Louis University researchers have uncovered new answers about why cells rapidly age in children with a rare and fatal disease.
Research from a UC Santa Cruz Genomics Institute-affiliated team just published in the journal Nature Biotechnology attempts to close huge gaps remain in our genomic reference map. The research uses nanopore long-read sequencing to generate the first complete and accurate linear map of a human Y chromosome centromere. This milestone in human genetics and genomics signals that scientists are finally entering a technological phase when completing the human genome will be a reality.
For the first time, cellular machines called ribosomes -- which create proteins in every cell of the body -- have been linked to blood stem cell differentiation. The findings, published today in Cell, have revealed a potential new therapeutic pathway to treat Diamond-Blackfan anemia.
One family of genes allows cells to adapt to daily changes in environmental conditions by adjusting their internal 'body clock,' the circadian clock responsible for regular sleep-wake cycles. The new discovery by University of Tokyo scientists reveals for the first time that circadian regulation may be directly connected to cellular stress.
A small, daily dose of Viagra significantly reduces colorectal cancer risk in an animal model that is genetically predetermined to have the third leading cause of cancer death, scientists report. Viagra cut in half the formation of polyps, an abnormal and often asymptomatic clump of cells on the lining of the intestines that may become cancer, says Dr. Darren D. Browning, cancer researcher at the Georgia Cancer Center and Department of Biochemistry and Molecular Biology at the Medical College of Georgia at Augusta University.
In the largest study of its kind, nine novel genes for osteoarthritis have been discovered by scientists from the Wellcome Sanger Institute and their collaborators. Results of the study, published today in Nature Genetics, could open the door to new targeted therapies for this debilitating disease in the future.
In the largest study of its kind, nine novel genes for osteoarthritis have been discovered by scientists from the University of Sheffield and their collaborators.
In Nature Biotechnology, an international team including scientists at the US Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility, present a reference catalog of rumen microbial genomes and isolates cultivated and sequenced from the Hungate1000 collection. One of the largest targeted cultivation and sequencing projects to date, the collection was produced through the coordinated efforts of rumen microbiology researchers worldwide.
Every year, approximately 12 million adults in the US are diagnosed with Chronic Obstructive Pulmonary Disease, and 120,000 die from it. For people with COPD, Haemophilus influenzae, a bacterium, can be particularly dangerous. Now, researchers have unraveled how the bacterium adapts quickly, which may open new avenues for therapy for COPD and other diseases such as ear infections or pneumonia.