NAFLD is the most common cause of liver damage, and can lead to liver cirrhosis and death. It affects nearly 1 in 4 people across the globe. It often is associated with obesity, abnormally high amounts of lipids in the blood, and type 2 diabetes. In the US, the number of NAFLD cases is expected to grow to more than 100 million within the next decade, annually costing an estimated at $292 billion.
Chris Organ worked with an international group of scientists to sequence the genome of the tuatara, a reptile found only in New Zealand with an evolutionary history stretching back 250 million years.
Two common variants in the KIF3A gene increase the risk of young children having a dysfunctional skin barrier and developing the skin condition atopic dermatitis, according to study led by scientists at Cincinnati Children's.
In a recent study published in Genome Biology, researchers from the Max Planck Institute for the Science of Human History, Lund University and the Swedish Natural Historical Museum present analysis of the highest quality ancient Mycobacterium tuberculosis genome to date, suggesting the pathogen is much younger than previously believed.
Researchers at the University of Maryland have discovered a new role for a well-known plant molecule, providing the first clear example of ACC acting as a likely plant hormone. In Nature Communications, researchers show that ACC has a critical role in pollination and seed production by activating proteins similar to those in human and animal nervous systems. Findings could change textbooks and open the door for research to improve plant health and crop yield.
By tinkering with some of life's oldest components, astrobiologists hope to find clues about how life emerged. In a recent paper, a group led by Betül Kaçar at the University of Arizona report an unexpected discovery, hinting at an effect that prevents organisms from ever reaching evolutionary perfection.
A rational design approach created novel variants of adeno-associated viral (AAV) capsids. These have improved transduction properties in the mouse retina and cornea.
Chemists at Scripps Research have efficiently created three families of complex, oxygen-containing molecules that are normally obtainable only from plants. These molecules, called terpenes, are potential starting points for new drugs and other high-value products -- marking an important development for multiple industries. In addition, the new approach could allow chemists to build many other classes of compounds.
A recent paper published in The Economic Journal indicates that, in families with disabled children, the second born child is more adversely affected cognitively than the first-born child.
The larynx is larger, more variable in size, and has undergone faster rates of evolution in primates than in carnivores, according to a study published August 11, 2020 in the open-access journal PLOS Biology by Daniel Bowling of Stanford University, W. Tecumseh Fitch of the University of Vienna, and colleagues.