scientists find that a gene involved in the immune system called IDO2 plays a significant role in pancreatic ductal adenocarcinoma (PDAC), the most common type of pancreatic cancer. The discovery may help physicians provide better treatment options for patients.
Aspergillus is an important fungal genus, with roles in agriculture, biotechnology, human health, enzyme production and food fermentation Reported in Nature Genetics, a team led by scientists at the Technical University of Denmark, the US Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility, and the Joint Bioenergy Institute (JBEI), a DOE Bioenergy Research Center, present the first large analysis of an Aspergillus fungal subgroup, section Nigri.
University of Queensland-led research recreating 450 million-year-old enzymes has resulted in a biochemical engineering 'hack' which could lead to new drugs, flavours, fragrances and biofuels. Professor Elizabeth Gillam from UQ's School of Chemistry and Molecular Biosciences said the study showed ancient enzymes could survive high temperatures and that this could help create chemicals cheaply and at scale.
Researchers in the lab of Charles Danko at the Baker Institute for Animal Health have developed a new tool to study genetic 'switches' active in glioblastoma tumors that drive growth of the cancer. In a new paper in Nature Genetics, they identified key switches in different types of tumors, including switches linked to how long a patient survives.
Researchers have demonstrated a new way to sequence proteins that is much more sensitive than existing technology, identifying individual protein molecules rather than requiring millions of molecules at a time. The advance could have a major impact in biomedical research, making it easier to reveal new biomarkers for the diagnosis of cancer and other diseases, as well as enhance our understanding of how healthy cells function.
Pioneering research into the mechanisms controlling gene activity in the brain could hold the key to understanding Alzheimer's disease and might help identify effective treatments in the future.
New research suggests that rising childhood obesity rates are causing more adolescents to develop a debilitating hip disease requiring urgent surgery.
The MSU-DOE Plant Research Laboratory has genetically tuned a plant to become highly resistant to insect attacks. But becoming such a fortress compromises its growth and procreative capabilities.
New research led by the University of Sydney has revealed the life expectancy of chocolate Labradors is significantly lower than their black and yellow counterparts.
Geneticists have assembled the largest sets of African genomic data available to date, creating a resource that will help researchers understand the genetic structure of Africa as well as the effects of genetic variation on protein function and disease. The findings underscore the importance of including globally diverse participant cohorts in genetics research, and were presented in a plenary session at the American Society of Human Genetics (ASHG) 2018 Annual Meeting in San Diego, Calif.