Researchers from the Indian Institute of Technology Bombay shed light on the origins of Mimivirus and other giant viruses, helping us better understand a group of unique biological forms that shaped life on earth. In their latest study published in Molecular Biology and Evolution, the researchers show that giant viruses may have come from a complex single-cell ancestor, keeping DNA replication machinery but shedding genes that code for other vital processes like metabolism.
A team of researchers at Gladstone Institutes and UC San Francisco (UCSF) has adapted CRISPR-Cas9 for use in monocytes and shown the potential utility of the technology for understanding how the human immune system fights viruses and microbes. Their results were published online today in the journal Cell Reports.
A team of Oregon State University scientists has discovered a new class of anti-cancer compounds that effectively kill liver and breast cancer cells.
DNA is composed of nucleobases represented by the letters A, T, G and C. They form the basis of the genetic code and are present in all living beings. But in a bacteriophage, another base, represented by the letter Z, exists. This exception, the only one observed to date, has long remained a mystery. Scientists from the Institut Pasteur and the CNRS, in collaboration with CEA, have now elucidated the biosynthesis pathway of this base.
They are some of the most beautiful, and elusive, animals on the plant. Leopards. In a major scientific step, the whole genome DNA sequence of 23 individual leopards have been interpreted.
Tepary beans--a high protein legume common to the southwest United States and Mexico--may hold the key to adapting bean crops for the increasingly harsh conditions brought on by a changing climate, according to research led by University of Saskatchewan (USask) and Michigan State University.
To better understand how PIF proteins affect apical hook development, scientists from the Institute of Botany of the Chinese Academy of Sciences recently investigated their roles in an organ specific manner.
Dr. HAN Fangpu's group from the Institute of Genetics and Developmental Biology of the Chinese Academy of Sciences reports the identification and functional study of the maize Knl1 gene in an article published online in PNAS.
Researchers at the University of Bristol have discovered how microbes responsible for human African sleeping sickness produce sex cells.
Scientists have developed a novel genetic sensor called a "CopyCatcher," which capitalizes on CRISPR-based gene drive technology, to detect instances in which a genetic element is copied precisely from one chromosome to another throughout cells in the body of a fruit fly. Next-generation CopyCatcher systems have the potential to measure how often such perfect copying might take place in different cells of the human body.