An antibiotic candidate compound shelved in the 1970s in favour of more worthwhile drugs could be worth a second look, new research has found.
A genetic mutation that occurred over 700 million years ago may have contributed to the development of certain organs in human beings and other vertebrates. This change, a random error in the evolutionary process, facilitated the connection of the gene networks involved in animal embryogenesis. The study, published in the journal Nature Communications, was participated in by experts from the Centre for Genomic Regulation, the Department of Genetics from the University of Barcelona Institute of Biomedicine, and the Anton Dohrn Zoological Station in Italy.
A fundamental prerequisite for life on earth is the ability of living organisms to adapt to changing environmental conditions. Physicists at the Technical University of Munich (TUM) and the University of California San Diego (UCSD) have now determined that the regulation mechanisms used by bacteria to adapt to different environments are based on a global control process that can be described in a single equation.
A single sand grain harbors up to 100,000 microorganisms from thousands of species.
Believe it or not, a tropical blood parasite native to Latin America could be harmful to Canadians. Infectious diseases like malaria or Zika may have dominated recent headlines but Chagas -- the 'Kissing Bug' disease -- is in the spotlight following the publication of a new case study in the Canadian Medical Association Journal. Experts from Winnipeg and Montreal warn natives of Latin America and their offspring are at risk of contracting Chagas disease.
The declining trend of salmonellosis cases in the EU has levelled off according to the annual report on zoonotic diseases published today.
Millions of bats in North America have been wiped out by the disease white-nose syndrome caused by the fungus Pseudogymnoascus destructans, and scientists worry that a catastrophic reduction in the bat population will have pervasive ecological repercussions. Now, a new study in mBio shines light on where the fungus came from and how it spreads.
The honey bee gut is colonized by specialized bacteria that help digest components of the floral pollen diet and produce molecules that likely promote bee health. In a study publishing Dec. 12, in the open access journal PLOS Biology, a group of researchers led by Philipp Engel at the University of Lausanne and ETH Zürich, Switzerland, have uncovered which bacterial species perform which specific digestive functions in the bee gut.
Researchers have identified a promising new strategy to fight infections and cancer. They uncovered a novel function for a protein known as 'Runx3' that is key to the development of killer T cells -- immune cells important for fighting infections and cancer. The researchers believe Runx3, if properly directed, could be combined with other approaches to help T cells recognize and destroy tumor cells and enhance vaccine efficacy.
Although the insidious bacterium Salmonella typhi has been around for centuries, very little is actually known about its molecular mechanisms. A new study from researchers at the College of Veterinary Medicine addresses this knowledge gap and may lead to novel, targeted treatments.