In collaboration with teams from the Czech Republic and Japan, researchers from the Institut Pasteur, (AP-HP), and (AP-HM) have identified the likely origin of the cross-reactivity between cypress pollen, peaches and citrus fruits. Their work has shown that these sources contain allergens belonging to a new family of proteins involved in pollen food associated syndrome. This discovery, published in JACI on Aug. 3, paves the way for the development of novel allergy diagnostic tests.
Genomic instability is the main risk factor for tumor development in humans. Therefore understanding its origin and and exploring therapeutic targets is paramount. Histone 1 silences a region of the genome that causes irreparable DNA damage when translated and is lethal for the organism.
In a recent report published in Nature Microbiology, University of Hawai'i at Mānoa (UHM) oceanography professor Ed DeLong and his team report the largest single-site microbiome gene catalog constructed to date. With this new information, the team discovered nutrient limitation is a central driver in the evolution of ocean microbe genomes.
Wheat growers of the inland Pacific Northwest have been slow to adopt no-till farming, in part because short-term residue accumulation can encourage fungal soil-borne disease outbreaks. But over longer periods, researchers at Washington State University and the University of Idaho noticed fewer outbreaks in fields where no-till was practiced for multiple seasons. New and cutting-edge research featured in Phytobiomes, an open-access journal of APS, paves the way for further study of this phenomenon.
Researchers from ETH Zurich and the University of Vienna have discovered a type of bacteria that uses tiny daggers to prevent itself from being eaten by amoebae. The scientists also resolved the three-dimensional structure of the mechanism that allows the micro-daggers to be shot quickly.
A new Pathology Atlas is launched today with an analysis of all human genes in all major cancers showing the consequence of their corresponding protein levels for overall patient survival. The difference in expression patterns of individual cancers observed in the study strongly reinforces the need for personalized cancer treatment based on precision medicine.
Treatment of tuberculosis involves a combination of several drugs, sometimes including drugs from a class known as fluoroquinolones. Using computer simulations, scientists have shown that the fluoroquinolone known as moxifloxacin may be superior to two other commonly used fluoroquinolones, according to a new paper in PLOS Computational Biology.
Children with lower diversity of microbial species in their intestines are more susceptible to severe infection with the Entamoeba histolytica parasite, according to a new study published in PLOS Pathogens.
Airplanes, electronics and solar cells are all in demand, but the materials holding these items together -- epoxy thermosets -- are not environmentally friendly. Now, a group reports in ACS' journal Macromolecules that they have created a plant-based thermoset that could make devices 'greener.'
Even with a growing body of research on microorganisms and humans in indoor environments, many of their interconnections remain unknown, says a new report by the National Academies of Sciences, Engineering, and Medicine. The report proposes a research agenda to gain a more comprehensive understanding of the formation, dynamics, and functions of indoor microbiomes that can guide improvements to current and future buildings as well as enhance human health and well-being.