
Research pinpoints unique drug target in antibiotic resistant bacteria
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Researchers have identified a critical mechanism that allows deadly bacteria to gain resistance to antibiotics.
MIT engineers have characterized the properties of the protective membrane around tumors and found that this lining may be a good target for therapies to prevent metastasis.
According to a UN-agreement, assistance dogs like guide dogs, signal dogs and medical response dogs are welcome in hospitals and other public places. However, in practice, they are regularly refused entry. Hygiene reasons are often given as the main argument for this. Research by Utrecht University now shows that the paws of assistance dogs are cleaner than the shoe soles of their users, and thus, paw hygiene is no reason to ban assistance dogs from hospitals.
The use of CAR T-cells reprogrammed to 'recognize' Cryptococcus spp. proved effective to combat the infection in vitro and in mice.
Glycine can stimulate or inhibit neurons in the brain, thereby controlling complex functions. Unraveling the three-dimensional structure of the glycine transporter, researchers have now come a big step closer to understanding the regulation of glycine in the brain. These results, which have been published in Nature, open up opportunities to find effective drugs that inhibit GlyT1 function, with major implications for the treatment of schizophrenia and other mental disorders.
The illegal wildlife trade is often seen as one of the major gateways to zoonotic diseases, that spread from animals to humans. While the illegal trade in tigers, ivory, rhino horn, pangolins and primates is of paramount concern for public health, Professor Nijman says the legal wildlife trade should be of equal concern.
New ISB research sheds light on how interspecies interactions arise, evolve and are maintained. The results, published in The ISME Journal, provide a new window to understand the key roles of these interactions in industrial applications, and in the health and disease of humans, animals and plants.
Some plant viruses systemically infect plants and cause huge losses in yield though our understanding of how systemic infections occur is largely unknown. A new study from the College of Biological Sciences at China Agricultural University provides extends our understanding of how virus-host interaction determines the systemic spread of a virus in different plant hosts.
UC San Diego School of Medicine researchers develop an automated process to test city sewage for SARS-CoV-2, allowing them to forecast the region's COVID-19 caseload one to two weeks ahead of clinical diagnostic reports.
Mitochondria are present in almost all eukaryotic cells and supply them with energy. Until now, it was assumed that only mitochondria can act as the cells' energy providers. Scientists at the Max Planck Institute for Marine Microbiology have now discovered that symbiotic bacteria can fulfil this function too. Their findings shed a completely new light on the survival of simple eukaryotes in oxygen-free environments. These results have been published in the renowned scientific journal Nature.