Würzburg researchers have developed a new analysis technique that sheds more light on viral infections. They used the new method to demonstrate that virus-infected cells produce far more infection-related proteins and peptides than previously thought.
In Nature Biotechnology, an international team including scientists at the US Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility, present a reference catalog of rumen microbial genomes and isolates cultivated and sequenced from the Hungate1000 collection. One of the largest targeted cultivation and sequencing projects to date, the collection was produced through the coordinated efforts of rumen microbiology researchers worldwide.
One in four drugs with human targets inhibit the growth of bacteria in the human gut. These drugs cause antibiotic-like side-effects and may promote antibiotic resistance, EMBL researchers report in Nature on March 19.
Bacteria and Archaea must have evolved from the putative Last Universal Common Ancestor (LUCA). One hypothesis is that this happened because the cell membrane in LUCA was an unstable mixture of lipids. Now, scientists from the University of Groningen and Wageningen University have created such a life form with a mixed membrane and discovered it is in fact stable, refuting this hypothesis.
Scientific recipes to successfully grow and study gut bacteria in the lab: that's what EMBL scientists are publishing in Nature Microbiology on March 19. They report on the nutritional preferences and growth characteristics of 96 diverse gut bacterial strains. Their results will help scientists worldwide advance our understanding of the gut microbiome.
Researchers from the Department of Molecular Biology and Genetics and from the Department of Biomedicine at Aarhus University have collaboratively developed and described a llama-antibody that might have significant impact for future diagnostics and treatment of, e.g., kidney diseases.
One of the biggest current threats to global health is the rise of multi-drug resistant bacteria, caused by the spreading of antibiotic resistance amongst them. In an attempt to help fight this threat, EMBL researchers have unraveled the molecular basis of a major antibiotic resistance transfer mechanism. They also developed molecules and a proof-of-principle for blocking this transfer. Cell publishes their results on March 15.
Interactions between Chlamydia trachomatis proteins and host cell proteins help determine whether the bacterium leaves an infected cell via breakdown of the cellular membrane (lysis) or in a membrane-bound package, according to new research published in PLOS Pathogens by Phu Hai Nguyen of the National Institutes of Health, US, and colleagues.
A team led by scientists from Scripps Institution of Oceanography at the University of California San Diego and the J. Craig Venter Institute (JCVI) has demonstrated that the excess carbon dioxide added to the atmosphere through the combustion of fossil fuels interferes with the health of phytoplankton which form the base of marine food webs.
How will the farms of the future feed a projected 9.8 billion people by 2050? Berkeley Lab's 'smart farm' project marries microbiology and machine learning in an effort to reduce the need for chemical fertilizers and enhance soil carbon uptake, thus improving the long-term viability of the land while increasing crop yields.