An adult mouse model reveals that changes in lattice-like structures in the brain known as perineuronal nets are necessary to 'capture' an auditory fear association and 'haul' it in as a longer-term memory.
Scientists at the University of Bath funded by Cancer Research UK have custom-built a molecule which stops breast cancer cells from multiplying in laboratory trials, and hope it will eventually lead to a treatment for the disease.
New research results from Aarhus University and New York University show how active transport of potassium can be achieved by a membrane protein complex that has roots in both ion pump and ion channel super-families. The results, which have just been published in Nature, shed new light on what define channels and pumps.
A team of researchers from the University of Würzburg has discovered an interesting enzyme in the pathogens responsible for African sleeping sickness: It could be a promising target for drugs.
Biofilms are slimy, glue-like membranes that are produced by microbes in order to colonize surfaces. They protect microbes from the body's immune system and increase their resistance to antibiotics. Biofilms represent one of the biggest threats to patients in hospital settings. But there is good news -- Canadian scientists have developed a novel enzyme technology that prevents the formation of biofilms and can also break them down.
Researchers have found that genes for coronary heart disease (CAD) also influence reproduction, so in order to reproduce successfully, the genes for heart disease will also be inherited.
Different types of memories stored in the same neuron of the marine snail Aplysia can be selectively erased, according to a new study by researchers at Columbia University Medical Center (CUMC) and McGill University and published today in Current Biology.
Research from the Stowers Institute provides evidence suggesting that cancer cells might streamline their genomes in order to proliferate more easily. The study, conducted in both human and mouse cells, shows that cancer genomes lose copies of repetitive sequences known as ribosomal DNA. While downsizing might enable these cells to replicate faster, it also seems to render them less able to withstand DNA damage.
Duke researchers have discovered a unique repair mechanism in the developing backbone of zebrafish that could give insight into why spinal discs of longer-lived organisms like humans degenerate with age. The repair mechanism protects fluid-filled cells of the notochord, the precursor of the spine, from mechanical stress. Notochord cells eventually form the gelatinous center of intervertebral discs, the structures that often degenerate with age to cause back and neck pain.
A developing fetus bathes in a mixture of cellular secretions and proteins unique to its mother's uterus. Before fertilization, the pH of uterine fluid helps create a conducive environment for sperm migration, and afterward, its volume supports the embryo as it implants onto the wall of the uterus. Recent evidence, presented in Trends in Molecular Medicine, suggests that uterine fluid may play another role in embryonic development: communicating the mother's outside conditions to the fetus,