Developed and tested at the University of Huddersfield, the compound, containing ruthenium, is attracted to the vulnerable cancer cells, whilst leaving healthy cells untouched.
In the first study of its kind, researchers characterized the skin microbiome of a population of free-ranging snakes to begin to understand how the animals' environmental microbial community may promote disease resistance as well as how it may be disrupted by infection.
Mushrooms from the Far East area contain the natural chemical compounds, which could be used for the design of the novel drugs with highly specific anti-tumor activities and low-toxicity. These compounds may offer new avenues for oncology, providing us with either stand-alone alternatives to chemotherapy, chemopreventive medicines, or drugs to be used in combination with other therapies.
Various fungi are known to infect insects and alter their behavior, presumably to assist in spreading fungal spores as widely as possible. But little is known about how the fungi affect behavior. UC Berkeley scientists have now found a fungus that infects the common lab fly, Drosophila melanogaster, providing a model in which to explore behavior-manipulating fungi. They found that the fungus invades the nervous system first while slowly eating the fly's fat and organs.
When dairy cattle consume aflatoxin-contaminated feed, they are lethargic, their appetite wanes, they produce less milk, and their immune system goes awry. Some of those symptoms relate to oxidative stress, in which dangerous free-radicals bounce around, damaging cells. In a new study, researchers at the University of Illinois investigated the potential of injectable trace minerals to reduce the damage and keep dairy cows healthier.
Under warming conditions, arctic wolf spiders' tastes in prey might be changing, according to new research by Washington University in St. Louis -- initiating a new cascade of food web interactions that could potentially alleviate some impacts of global warming.
Candida albicans is a fungal species causing infection in humans. A team of scientists decided to sequence and analyze the genomes of 182 strains of C. albicans from around the world. They confirmed the clonal reproduction of this human pathogen but also showed that parasexual reproduction, previously only observed in a laboratory setting, contributes to the genetic diversity of C. albicans and therefore also to its ability to adapt to new environments and rid itself of deleterious mutations.
Genomic analysis suggests that asexual reproduction is the rule among individuals of the species Trichophyton rubrum. The authors believe that this factor should be considered in drug development.
Using systems biology, researchers successfully identified previously unknown protein targets of plant pathogens in the flowering plant Arabidopsis thaliana, employing some of the same methods used to analyze social networks or biological networks. Their theoretical framework, they say, could help analyze other interactions between species to reveal pathogen contact points.
Pollution is changing the fungi that provide mineral nutrients to tree roots, which could explain malnutrition trends in Europe's trees.