In Central America, Chagas disease, or American trypanosomiasis, is spread by the 'kissing bug' Triatoma dimidiata. By collecting DNA from the guts of these bugs, researchers reporting in PLOS Neglected Tropical Diseases have described patterns in the behavior of the bugs, the strain of parasite, and the communities of microbes that interact with the parasite.
Researchers at the University of New Hampshire have found that the swell of infestations of winter ticks -- which attach themselves to moose during the fall and feed throughout the winter -- is the primary cause of an unprecedented 70 percent death rate of calves over a three-year period.
A radical new approach combining archaeology, genetics and microscopy can reveal long-forgotten secrets of human diet, sanitation and movement from studying parasites in ancient poo, according to new Oxford University research.
Host decoy traps which mimic humans or cattle by combining odor, heat and a conspicuous visual stimulus could be effective at measuring and controlling outdoor-biting mosquitoes in malaria endemic regions, according to a study published in the open access journal Parasites & Vectors.
Shrimp help keep fish clean -- and scientists have identified the 'cleaner shrimp' with the most talent for reducing parasites and chemical use in farmed fish.
Children around the world are suffering from unnoticed infections that are stunting their growth and mental development, new research from an international coalition of scientists reveals.
A research team from Singapore demonstrated how the cyto-adhesion of plasmodium-infected red blood cells is enhanced at febrile temperatures. Through dual-micropipette step-pressure technique, they studied the interactions between P. falciparum-infected RBCs (iRBCs) and Chinese Hamster Ovary cells expressing Chondroitin sulfate A (CHO-CS), to discover that adhesion force and percentage are elevated at febrile temperature. The team also identified that significant increase of phosphatidyserine on iRBCs is the likely contributor to the elevated cyto-adhesion.
A research group led by Assistant Professor Rajesh Chandramohanadas from the Singapore University of Technology and Design (SUTD) documented the permissible limits of a number of chemicals that are often part of anti-malarial efficacy tests. Their results provide a previously undetermined dataset on drug reconstitution conditions at which both the red cell integrity and plasmodium growth and proliferation are not compromised.
Scientists from Massachusetts Institute of Technology (MIT), Singapore-MIT Alliance for Research and Technology (SMART) and Nanyang Technological University, Singapore (NTU Singapore) have discovered a potential treatment that could be effective against severe malaria and even drug-resistant malaria.
For decades, scientists have been trying to develop a vaccine that prevents mosquitoes from spreading malaria among humans. This unique approach -- in which immunized humans transfer anti-malarial proteins to mosquitoes when bitten -- is called a transmission-blocking vaccine (TBV). A new biotech advancement moves us closer to this goal. If successful, it could help reduce the spread of the disease, which kills more than 400,000 people annually.