Clinical studies by scientists at British American Tobacco indicate that when smokers switched completely from conventional cigarettes to glo, their exposure to certain harmful chemicals was significantly reduced. In some cases, the reductions were the same as those in smokers who quit altogether. These data suggest the potential of glo as a reduced-risk product. glo is a tobacco heating product designed to heat rather than burn tobacco. Tests show that glo vapour has around 90-95 percent less toxicants than smoke.
Cetuximab (CET) is a monoclonal antibody that inhibits epidermal growth factor receptor (EGFR) used for immunotherapy of different types of cancer. This study describes the development and full validation of a new enzyme-linked immunosorbent assay (ELISA) with high sensitivity and selectivity for bioanalysis of CET.
A new Annals of Neurology study provides insight into the neurobiology of dying. For the study, investigators performed continuous patient monitoring following Do Not Resuscitate - Comfort Care orders in patients with devastating brain injury to investigate the mechanisms and timing of events in the brain and the circulation during the dying process.
Significant amounts of toxic metals, including lead, leak from some e-cigarette heating coils and are present in the aerosols inhaled by users, according to a study from scientists at Johns Hopkins Bloomberg School of Public Health.
A team of scientists, affiliated with South Korea's Ulsan National Institute of Science and Technology (UNIST) has unveiled that the bacterium Chromobacterium piscinae produces cyanide, an inhibitory molecule, to defend themselves in the battle against Bdellovibrio bacteriovorus HD100.
UL, the science safety company, and Johns Hopkins University have embarked on joint research that has resulted in findings that Artificial Intelligence (AI) is superior in finding toxic substances to traditional animal testing. Beyond being more effective, UL's Cheminformatics REACHAcross™ software computer processing can be performed in a matter of seconds and at a fraction of the cost to traditional testing methods.
Researchers at the University of Pennsylvania's School of Engineering and Applied Science have demonstrated the feasibility of their 'organ-on-a-chip' platform in studying how drugs are transported across the human placental barrier.
This review provides specific examples of metabolomics applications in the field of clinical pharmacology and precision medicine with a focus on the therapeutic management of cancer and in the translation of these results to the clinics.
Two lineages of dangerous arachnids found in Australia--long classified as distantly related in the official taxonomy--are, in fact, relatively close evolutionary cousins. The lineages include the most venomous spiders in the world. The findings could help in the development of novel antivenoms, as well as point to new forms of insecticides.
researchers from the Wyss Institute for Biologically Inspired Engineering at Harvard University, Instituto Superior Técnico (IST, Portugal), Boston Children's Hospital, and Harvard Medical School (HMS) have published a study using an organ-on-a-chip (Organ Chip) model of the human gut that reveals the intestinal blood vessel cells may play an important part in radiation-induced intestinal injury, and it confirms that a potential radioprotective drug, dimethyloxaloylglycine (DMOG), suppresses the intestine's responses to radiation injury.