Mechanisms that govern HIV transcription and latency differ in the gut and blood, according to a study published Nov. 15 in the open-access journal PLOS Pathogens by Steven Yukl of San Francisco Veterans Affairs Medical Center and the University of California, San Francisco, and colleagues. According to the authors, the findings could inform new therapies aimed at curing HIV.
A vaccine used to prevent dogs from contracting the deadly, parasitic disease canine leishmaniasis also can be used to treat currently infected dogs, found Morris Animal Foundation-funded researchers at the University of Iowa, providing a new avenue of treatment for millions of infected dogs globally.
While making smart glue, a team of engineers discovered a handy byproduct: hydrogen peroxide. In microgel form, it reduces bacteria and virus ability to infect by at least 99.9 percent.
Antibodies against dengue virus make it easier for Zika to infect certain immune cells in the placenta, called Hofbauer cells.
Two new studies provide evidence that previous Dengue infection in pregnant mothers may lead to increased severity of Zika in babies, and that previous Zika infection in mice mothers may increase severity of Dengue infection in their pups. The research, publishing Nov. 14 in the journal Cell Host & Microbe, supports that maternally acquired antibodies for one virus can assist infection by the other by a process unique to flaviviruses.
A research team based in Japan led by Kanazawa University has demonstrated the effect of osteopontin on hepatitis C virus replication and interferon signaling in cancer stem cells. Their research sheds light on a novel therapeutic target for treating hepatocellular carcinoma.
Researchers have discovered a possible path forward in preventing the development of cancers tied to two viruses, including the virus that causes infectious mononucleosis --more commonly known as mono or the 'kissing disease' -- that infects millions of people around the globe each year.
Vaccinia virus, a poxvirus closely related to smallpox and monkeypox, tricks cells it has infected into activating their own cell movement mechanism to rapidly spread the virus in cells and mice, according to a new UCL-led study published in Nature Microbiology.
Salmonella in eggs, noroviruses in frozen berries, hepatitis E viruses in domestic pigs and wild boar and resistant bacteria in meat: pathogenic microorganisms are one of the most common causes of foodborne illnesses. Every year, they cause more than 100,000 cases of disease in Germany -- some of them fatal.
Washington State University researchers for the first time have shown that they can use electrical fields to gain valuable information about the tiny, floating vesicles that move around in animals and plants and are critically important to many biological functions.