Researchers have discovered crucial new processes that allow malaria parasites to escape red blood cells and infect other cells, offering potential new treatment targets. The team are already working with pharmaceutical companies to use this knowledge to develop new antimalarial drugs - a critical step in the battle against drug-resistant malaria.
The Ebola virus disease (EVD) outbreak in 2014-2015 disrupted the provision of healthcare in Sierra Leone, Guinea, and Liberia. In a research article published this week in PLOS Medicine, Bradley Wagenaar, of the University of Washington, and colleagues quantify the health system output losses in Liberia during and in the immediate aftermath of the EVD outbreak, and the recovery of the health systems in the two years following.
Scientists at Joslin Diabetes Center have identified four viruses that can produce insulin-like hormones that are active on human cells. The discovery brings new possibilities for revealing biological mechanisms that may cause diabetes or cancer.
Scientists have mapped for the first time the midgut metabolites of the Aedes aegypti, the mosquito that can transmit viruses that cause dengue, Zika, chikungunya and yellow fever to humans.
The antioxidant drug ebselen can prevent sexual transmission of Zika virus from male to female mice, according to new research published in PLOS Pathogens by Yogy Simanjuntak and colleagues at Academia Sinica, Taipei, Taiwan. The results hint at a potential role for ebselen in preventing Zika spread among humans.
As globalization and climate change spread tropical diseases around the globe, not all populations are equally susceptible to infection. Gene variants common in people of Asian and European ancestry, for instance, make them more prone than those of African origin to developing severe dengue shock syndrome, according to a new study in PLOS Neglected Tropical Diseases.
Scientists at Imperial College London have become the first in the world to test how pathogens interact with artificial human organs.
Researchers at the University of Illinois at Chicago have now identified a small drug molecule that can clear the HSV-1 infection in the cells of the cornea -- the clear outer layer of the eyeball -- and works completely differently than the currently-available drugs, making it a promising potential option for patients who have developed resistance.
Researchers have discovered a new ranging behavior in male badgers, which will aid the implementation of a nationwide TB vaccination program, recently announced by the Department of Agriculture, Food and The Marine in Ireland.
Using stem cell therapy, Morris Animal Foundation-funded researcher Dr. Deanne Whitworth and her colleagues at the University of Queensland, have taken the first step toward developing an effective treatment for devil facial tumor disease (DFTD), which is decimating Tasmanian devils in the wild. The team's findings were recently published in Stem Cells and Development.