A team of Clemson University researchers wants to protect humans and other mammals from the debilitating and even deadly effects of African sleeping sickness. James Morris, a Clemson professor in the College of Science's department of genetics and biochemistry, said that studying the cause of the disease is vital because, although the transmission of African sleeping sickness by tsetse flies has been studied for more than 100 years, the secret to the underlying parasite's success remains largely a mystery.
Researchers at the University of New Hampshire have created an easy-to-make, low-cost injectable hydrogel that could help wounds heal faster, especially for patients with compromised health issues.
In a paper published recently in the journal Origins of Life and Evolution of Biospheres, UW-Madison researchers described initial steps toward achieving chemistries that encode information in a variety of conditions that might mimic the environment of prehistoric Earth.
A new method of selectively binding proteins to nanoparticles has been described by a team of German and Chinese researchers headed by Prof. Bart Jan Ravoo, a chemist at the "Center for Soft Nanoscience" at the University of Münster, Germany. The nanoparticles automatically recognize small proteins and enter into highly selective binding with them.
A study led by Dr. Ravi Muddashetty at InStem, Bangalore identified distinct markers to distinguish ribosomes that are specialized for producing specific sets of proteins and hinted that this specialization could be important for the development of the nervous system.
Monash researchers have shed new light on just how the fungal infection Candida albicans shape-shifts into a deadly version with hyphae or filaments that help it break through human tissues and into the bloodstream. Understanding this process is key to the development of drugs against this fatal infection.
A weapons of Staphylococcus aureus is α-toxin, which destroys host cells by forming pores in their membranes. Researchers at UNIGE have identified the mechanism that allows these pores to be harmful. They uncover how proteins of human cells assemble into a complex to which pores are docked. They also demonstrate that blocking the assembly of the complex by removing one of its elements allows pores to be removed from the membrane and cells to survive.
One of the body's largest macromolecules is the machinery that gloms onto DNA and transcribes it into mRNA, the blueprint for proteins. But the molecule, TFIID, is complex with lots of floppy appendages, which makes it hard to obtain a clear picture of its structure. Using state-of-the-art cryo-electron microscopy detectors and computer analysis, UC Berkeley scientists have captured unprecedented detail of how TFIID's structure changes as it binds to DNA and recruits other proteins.
Every day, thousands of trained K9 dogs sniff out narcotics, explosives and missing people. These dogs are invaluable for security, but they're also expensive. Duke researchers have made the beginning steps toward an artificial 'robot nose' device that officers could use instead of dogs. The heart of the system would be living odor receptors grown from mouse genes that respond to target odors, including the smells of cocaine and explosives.
Researchers at Portland State University discover that vitamin D plays a key role in embryonic development in vertebrates and by blocking vitamin D in embryos of zebrafish, researchers were able to induce dormancy in a species that doesn't enter dormancy. The discovery could have major implications in human health research.