Researchers develop a hydrogel whose stiffness and permeability to cells can be controlled with light
Puberty is a period of extensive changes of body morphology and function. As much as we are familiar with these life-altering changes, relatively little is known about what sets the whole process in motion. Thanks to studies in the tiny worm C. elegans, the group of Helge Großhans is getting closer to understanding how the onset of puberty is genetically controlled. Recently they uncovered a mechanism that initiates sexual organ maturation.
Alexey Moskalev, Ph.D., Head of the Laboratory of Molecular Radiobiology and Gerontology Institute of Biology, and co-authors from the Institute of biology of Komi Science Center of RAS, Engelgard's Institute of molecular biology, involved in the study of the aging mechanisms and longevity of model animals announce the publication of a scientific article titled: 'The Neuronal Overexpression of Gclc in Drosophila melanogaster Induces Life Extension With Longevity-Associated Transcriptomic Changes in the Thorax' in Frontiers in Genetics - a leading open science platform.
Bacteria produce a cocktail of various bioactive natural products in order to survive in hostile environments with competing (micro)organisms. In the current issue of Nature Chemical Biology, researchers at Goethe University demonstrate that they do so by modifying basic structures, similar to the approach taken in pharmaceutical research.
Scientists build artificial cells as models of primitive cells. Research team have constructed artificial cells using minimal components that are able to supply energy to drive gene expression inside a microcompartment, thus these artificial cells can produce energy that helps synthesize parts of the cells themselves. This work marks an important milestone in constructing artificial autotrophic cells, and may shed light on how primordial cells used sunlight as an energy source early in life's history.
Selective serotonin reuptake inhibitors (SSRIs) are the most commonly prescribed medication for major depressive disorder (MDD), yet scientists still do not understand why the treatment does not work in nearly thirty percent of patients with MDD. Now, Salk Institute researchers have discovered differences in growth patterns of neurons of SSRI-resistant patients. The work has implications for depression as well as other psychiatric conditions such as bipolar disorder and schizophrenia that likely also involve abnormalities of the serotonin system in the brain.
A Rice University-led study discovers a mechanism by which molecules affect the plasmonic response of gold nanorods. The mechanism could be used to enhance applications like catalysis that involve plasmon-driven chemistry.
Weeds often emerge at the same time as vulnerable crop seedlings and sneak between plants as crops grow. How do farmers kill them without harming the crops themselves? In a new University of Illinois study, researchers identify genes and metabolic pathways responsible for safener efficacy in grain sorghum.
Superbugs, also known as Gram-negative bacteria, are causing a global health crisis. To combat antibiotic-resistant infections, researchers are pursuing clever new ways to thwart the bacteria's tough defense system. Now, they have uncovered some of the previously unknown machinery that builds the bacterial outer membrane, information that could lead to new treatments for untreatable infections.
The creation of new library of mutants of the single-celled photosynthetic green alga, Chlamydomonas reinhardtii enabled a Carnegie- and Princeton University-led team of plant scientists to identify more than 300 genes that are potentially required for photosynthesis. Photosynthesis is the process by which plants, algae, and some bacteria convert energy from sunlight into carbohydrates -- filling our planet's atmosphere with oxygen as a byproduct.