A Colorado State University team of single-molecule biophysicists and biochemists have shed light on a long-obscured cellular process: a mammalian cell membrane's relationship with a scaffolding underneath it, the cortical actin cytoskeleton. For the first time, the CSU team has made real-time observations of this cytoskeleton acting as a barrier that organizes proteins on the cell's surface, effectively playing traffic cop on the cell's membrane activities.
When many genes regulate a single trait, they commonly work together in large clusters or 'networks.' Taking this into account allows better predictions of how an individual's genetic make-up affects the trait concerned. The risk of perceiving the importance of an individual gene incorrectly is also reduced. This has been shown by researchers at Uppsala University, through a detailed analysis of thousands of related yeast cells.
Researchers from Kumamoto University, Japan have developed an insulin release system with sustained and controllable delivery. The system combines two original technologies, SPRA and PPRX, which provide complimentary benefits for insulin delivery.
Development of new strategies and novel drug design to treat trophoblastic diseases and to provide pregnancy success are of crucial importance in maintenance the female reproductive health.
Researchers at Emory University and Georgia Tech demonstrated a connection between abnormal protein folding and the potential to kickstart chemical evolution in two new papers published by Nature Chemistry.
Sometimes cells spit out things we don't want them to -- like medications. Researchers have determined the three-dimensional structure of a tiny pump that expels, among other things, chemotherapy agents. This new knowledge could lead to the design of more effective drugs.
Successful results of a University of Liverpool-led trial that utilised nanotechnology to improve drug therapies for HIV patients has been presented at the Conference on Retroviruses and Opportunistic Infections (CROI) in Seattle, a leading annual conference of HIV research, clinical practice and progress.
Scientists at The Wistar Institute and Inovio Pharmaceuticals, Inc. have devised a novel DNA vaccine approach through molecular design to improve the immune responses elicited against one of the most important cancer antigen targets.
A Caltech-led study has shown that the electrical wire-like behavior of DNA is involved in the molecule's replication.
In a recent paper, Joel Eissenberg, Ph.D., professor of biochemistry and molecular biology at Saint Louis University, explores questions that stem from new advances in direct-to-consumer DNA tests, which have the effect of separating the physician-patient relationship from access to new personal health data.