Researchers from Carnegie Mellon University and Nanyang Technological University, Singapore have developed an organ-on-an-electronic-chip platform, which uses bioelectrical sensors to measure the electrophysiology of the heart cells in three dimensions. These 3D, self-rolling biosensor arrays coil up over heart cell spheroid tissues to form an 'organ-on-e-chip,' thus enabling the researchers to study how cells communicate with each other in multicellular systems such as the heart.
To walk or run with finesse, roaches and robots coordinate leg movements via signals sent through centralized systems. Though their moving parts are utterly divergent, researchers have devised handy principles and equations to assess how both beasts and bots locomote and to improve robotic gait.
Rice University scientists develop a nano-thermometer able to take temperatures inside cells. The technique takes advantage of the fluorescent properties of a modified molecular rotor and the viscosity of the cell.
The function of the visual photopigment rhodopsin and its action in the retina to facilitate vision is well understood. However, there remain questions about other biological functions of this family of proteins (opsins) and this has ramifications for our understanding of several evolutionary pathways. Now, an international research team led by the University of Göttingen has shown there are other functions of opsin outside vision and this provides insights into how the eye evolved. Their research was published in Current Biology.
A new study indicates that some exoplanets may have better conditions for life to thrive than Earth itself has. 'This is a surprising conclusion', said lead researcher Dr. Stephanie Olson, 'it shows us that conditions on some exoplanets with favorable ocean circulation patterns could be better suited to support life that is more abundant or more active than life on Earth.'
A team of scientists from Weill Cornell Medicine and The Rockefeller University has illuminated the basic mechanism of Piezo proteins, which function as sensors in the body for mechanical stimuli such as touch, bladder fullness, and blood pressure. The discovery is a feat of basic science that also opens up many new paths of investigation into the roles of Piezo proteins in human diseases and potential new therapeutic strategies.
In an article published in the peer-reviewed SPIE publication Neurophotonics, 'High density functional diffuse optical tomography based on frequency domain measurements improves image quality and spatial resolution,' researchers demonstrate critical improvements to functional Near Infrared Spectroscopy (fNIRS)-based optical imaging in the brain.
Researchers have developed artificial 'chameleon skin' that changes colour when exposed to light and could be used in applications such as active camouflage and large-scale dynamic displays.
Amyloid fibrils play a crucial role in neurodegenerative illnesses. Scientists from Heinrich Heine University Düsseldorf (HHU) and Forschungszentrum Jülich have now been able to use cryo-electron microscopy (cryo-EM) to decode the spatial structure of the fibrils that are formed from PI3K SH3 domains - an important model system for research. Although the fibrils examined are not themselves connected with an illness, the findings made and methods developed could serve to understand diseases such as Alzheimer's and Parkinson's.
Scientists from Russia, China, and the US have drawn the attention of the scientific community to one of the newest and most promising areas in bioprinting -- laser-induced forward transfer (LIFT). They have compared laser printing parameters, bioink composition, donor ribbons, and collector substrates for LIFT bioprinters, as well as post-printing treatments of fabricated materials -- all of this may affect the properties of printed tissues and organs. The details of the analysis were published in Bioprinting.