As indicated by a recently published study, short-term opioid use shifts a range of emotional responses to the positive direction. This may be one of the reasons behind the onset of opioid use disorder.
A team of researchers from Tokyo University of Science, Meiji University, and Tokyo University of Agriculture and Technology, led by Professor Takayuki Arazoe, has recently established a series of novel strategies to increase the efficiency of targeted gene disruption and new gene 'introduction' using the CRISPR/Cas9 system in the rice blast fungus Pyricularia (Magnaporthe) oryzae.
A new study from Children's Hospital of Philadelphia finds that a skin patch may be useful in treating children with a painful, chronic condition called eosinophilic esophagitis (EoE) triggered by milk. Among 20 children with EoE who wore Viaskin Milk -- a skin patch measuring just over an inch long containing trace amounts of milk protein -- nine saw an improvement in their symptoms and normalization of their biopsies after 11 months.
A dramatic rise in opioid overdose deaths among American veterans in recent years has happened mainly among veterans dying from heroin and synthetic opioids, a new study shows. The study highlights a pressing need to find and provide care to veterans who need help for use of non-prescription opioids, whether or not they are also taking prescription opioids.
A 5,000-year-old toy still enjoyed by kids today has inspired an inexpensive, hand-powered scientific tool that could not only impact how field biologists conduct their research but also allow high-school students and others with limited resources to realize their own state-of-the-art experiments.
A new study based on a mostly forgotten guide to medicinal plants, 'Resources of the Southern Fields and Forests,' focuses on three of the plants and shows they inhibit bacteria associated with wound infections.
Scientists at VCU Massey Cancer Center may have uncovered a primary method through which cancer cells exist undetected in an organism and received more than $1 million to investigate the potential for novel therapeutics that target and destroy cells in a specific state of tumor dormancy.
An analysis of 117 cancer drugs approved by the US FDA over a 20-year period finds the drugs took a median of 6.5 years to go from the first clinical trial in adults to the first trial in children. 'As a doctor taking care of young cancer patients, this is tremendously frustrating,' says lead researcher Steven DuBois, M.D. 'If I were a parent of a child with cancer, I wouldn't stand for this.'
A new type of non-addictive opioid developed by researchers at Tulane University and the Southeast Louisiana Veterans Health Care System accelerates recovery time from pain compared to morphine without increasing pain sensitivity, according to a new study published in the Journal of Neuroinflammation.
The anti-tumor protein p53 can decide on the life or death of a cell: If it detects damage in the cell's genome, the protein pushes the cell to suicide. New research conducted at Technical University of Munich (TUM) shows that this inborn cancer prevention only works when special proteins, known as chaperones, allow it to take place.