For more than a third of children living with epilepsy, the currently approved medications do not stop their seizures. Researchers at the Cumming School of Medicine have developed a new drug screening method to discover drugs to treat epilepsy.
Using a homemade, high-tech microscope, scientists have revealed how a cancer-causing virus anchors itself to our DNA. That discovery could pave the way for doctors to cure incurable diseases by flushing out viruses, including HPV and Epstein-Barr, that now permanently embed themselves in our cells.
A new international study led by University of Sydney has found that medication use increases in newly diagnosed dementia patients, particularly unnecessary or inappropriate medications.
Scientists have for the first time found direct causal links between the neurotransmitter dopamine and avoidance -- behavior related to pain and fear. Researchers have long known that dopamine plays a key role in driving behavior related to pleasurable goals, such as food, sex and social interaction. In general, increasing dopamine boosts the drive toward these stimuli. But dopamine's role in allowing organisms to avoid negative events has remained mysterious.
Using drug repurposing, a team of researchers led by animal biologists at Nagoya University has discovered compounds that can either shorten or lengthen the circadian rhythm in human cells. A hormone, also known as a common anti-aging supplement demonstrated period-shortening activities, and when it was fed to mice, jet lag symptoms were significantly reduced.
A new non-toxic method for delivering anti-cancer drugs to specific parts of the human body could mean the end of the severe and nasty side effects associated with many cancer therapies, according to researchers at Cardiff University's School of Pharmacy and Pharmaceutical Sciences.
Researchers at the University of Michigan Rogel Cancer Center designed this new delivery system -- a drug hidden in a nanodisc -- to increase the number of patients who can be treated successfully with cancer immunotherapy drugs.
A preliminary study suggests that an investigational drug may help increase protein levels in babies with spinal muscular atrophy. The open-label study is released today and will be presented at the American Academy of Neurology's 70th Annual Meeting in Los Angeles, April 21-27, 2018.
A group led by the Abramson Cancer Center of the University of Pennsylvania has proposed three solutions to maximize the clinical benefit and affordability of targeted cancer drugs.
Ibuprofen and other nonsteroidal anti-inflammatory drugs (NSAIDs) alone or in combination with acetaminophen are better at easing dental pain than opioids, according to new research conducted with the School of Dental Medicine at Case Western Reserve University.