Researchers used C. elegans as an animal model to investigate the importance of certain human genes for the treatment of schizophrenia.
Experiments with mice suggest that treatment with atorvastatin can attenuate adipose tissue remodeling, leading to rapid weight loss and muscle atrophy.
Common medications prescribed to treat heartburn, acid reflux and ulcers are linked to increased risks for kidney failure and chronic kidney disease, found a recent University at Buffalo study.
Most nonpharmacologic and pharmacologic interventions are more likely than no treatment to improve outcomes for women with either stress or urgency urinary incontinence (UI). Behavioral therapy, alone or in combination with other interventions, was found to be generally more effective than pharmacologic therapies alone. Findings from a systematic evidence review and network meta-analysis of clinical outcomes of nonpharmacologic and pharmacologic interventions for UI are published in Annals of Internal Medicine.
Study finds that performing catheter ablations on patients who suffer from both atrial fibrillation and carotid arterial disease reduces their risk of dementia and stroke compared to managing their care with medications.
Study finds that taking statins for heart disease cuts risk of second serious event in half, yet only 6 percent of patients are following as directed.
University of Cincinnati professor Jason Heikenfeld and his students have been creating new sensors on a wearable patch the size of a Band-Aid that stimulates sweat even when a patient is cool and resting. The sensor measures specific analytes over time that doctors can use to determine how the patient is responding to a drug treatment.
Dysregulation of the signaling pathway known as the beta-catenin-dependent Wnt can also cause embryo malformation and contribute for the development of breast and cervical cancer.
National and state trends for opioid prescriptions filled at US retail pharmacies are estimated from 2006 through 2017 in this analysis of data from outpatient prescribing records. Each year an average of nearly 234 million opioid prescriptions were filled. Several key measures of opioid prescribing varied among states.
Seven of the ten most frequent medications contain chiral agents. These are molecules that occur in right- or left-handed forms. During chemical synthesis both forms usually occur in equal parts and have to be separated afterward, because chirality determines the agent's effect in the body. Physicists at Goethe University have now succeeded in using laser light for the purpose of creating either right- or left-handed molecules.