An international research team led by Friedrich Schiller University in Jena has developed a highly sensitive cell model to study the complex effects -- and side effects -- of anti-inflammatory drugs, with the ultimate aim of preventing chronic inflammation.
Skin cells taken from patients with a rare genetic disorder are up to ten times more sensitive to damage from ultraviolet A (AVA) radiation in laboratory tests, than those from a healthy population, according to new research from the University of Bath.
Patients with interstitial lung disease -- a group of disorders causing progressive scarring of lung tissue -- are often prescribed various medications that specifically target their disease and others that treat their symptoms. A new Respirology study found that patients often experience significant burden associated with the treatment and management of their illness, and some are at risk of experiencing drug-disease interactions, or adverse outcomes that arise after receiving a drug that exacerbates their disease.
Inspired by the refined electrochemistry of electric car batteries, scientists have developed a battery-like system that allows them to make potential advancements for the manufacturing of medicines. Their new method avoids safety risks associated with a type of chemical reaction known as dissolving metal reduction. Their method would offer significant advantages over current methods of chemical manufacturing, but until now, has largely been sidelined due to safety considerations.
Researchers from Russian Academy of Sciences developed a new method for star-shaped nanoparticles synthesis based on laser irradiation. A wide range of customizable conditions provides an opportunity to create comfortable environment for various substances delivery to different types of cells. The results are published in Journal of Biophotonics. The research was supported by the Russian Science Foundation.
Scientists working in a range of disciplines joined forces to identify a new approach to combat African sleeping sickness. Fundamental research undertaken under the supervision of Professor Ute Hellmich of Johannes Gutenberg University Mainz (JGU) has revealed a promising strategy to develop a suitable agent.
A new Purdue University technique to analyze proteins expressed on cancer cells shows promise in more rapidly detecting these cell types in patients.
Patients with schizophrenia are often treated with more than one type of psychiatric medication, but a new study suggests that some combinations may be more effective than others.
Researchers from the Institute of Neurosciences of the University of Barcelona (UBNeuro) have identified a potential therapeutic strategy to treat Alzheimer's, according to a study published in Journal of Neuroscience. The study shows, in a model of the illness in mice, that astrocytes -- a type of cells in the brain -- are able to release proteins that favour survival of neurons.
Glowing pee may replace the biopsy needle: In detecting organ transplant rejection, a new nanoparticle has proven much faster and more thorough in the lab than a biopsy. When T cells mount their first attack on the organ's cells the nanoparticle sends an alarm signal into the urine that makes it fluoresce.