Little is known about the structures of our genetic material, chromosomes, which consist of long strings that -- according to our experience -- should be likely to become knotted. However, up to now it has not been possible to study this experimentally. Researchers at Johannes Gutenberg University Mainz (JGU) in Germany have now found that chromosomes may indeed be knotted.
This study examines how small-world networks occur within bigger and more complex structures.
It's really surprising: it turns out that among simple electronic circuits, built of just a few components, many of them behave chaotically, in an extremely complicated, practically unpredictable manner. Physicists from the Institute of Nuclear Physics Polish Academy of Sciences in Cracow have discovered, examined and described dozens of new, unusual circuits of this type. What is especially interesting is that one of the circuits generates voltage pulses very similar to those produced by neurons, only it does so a thousand times faster.
The JRC has launched a data challenge to crowdsource policy ideas for integration, inviting researchers to use a new visual dataset mapping migrants in Europe. The maps show residential patterns at high resolution across 8 EU countries.
Complete elimination of Human Immunodeficiency Virus (HIV) presents a challenge due to latent viral reservoirs within the body that can help re-establish infection. In a paper publishing this week in the SIAM Journal on Applied Mathematics, researchers propose a mathematical model that investigates the effects of drug parameters and dosing schedules on HIV latent reservoirs and viral load dynamics.
Using a computational approach known as deep learning, scientists have developed a new system to classify the shapes of red blood cells in a patient's blood. The findings, published in PLOS Computational Biology, could potentially help doctors monitor people with sickle cell disease.
New statistical simulations suggest that Northern Hemisphere flu pandemics are most likely to emerge in late spring or early summer at the tail end of the normal flu season, according to a new study published in PLOS Computational Biology by Spencer Fox of The University of Texas at Austin and his colleagues, Lauren Ancel Meyers (also at UT Austin) and Joel C. Miller at the Institute for Disease Modeling in Bellevue, Wash.
Fruit flies have surprising similarities to humans. The mysteries of a broad range of human conditions can be studied in detail in these organisms, however this often requires the use of expensive custom equipment. In a Community Page in the open-access journal PLOS Biology, Dr. Giorgio Gilestro from Imperial College London and colleagues present the ethoscope -- a cheap, easy-to-use and self-made customizable piece of equipment of their invention that can be used to study flies' behavior.
New research suggests that rare species of trees in rainforests may help safeguard biodiversity levels as the environment undergoes change.
In a paper published in Nature Communications, Christoph Adami, professor of microbiology and molecular genetics, and graduate student Thomas LaBar have provided a look at how certain species survive by evolving a greater ability to weed out harmful mutations -- a new concept called 'drift robustness.'