In a new study, a team from the University of Pennsylvania describes how X chromosome inactivation is regulated in the immune system's B cells as they develop in bone marrow and when they encounter antigens.
Breast cancer cells recycle ammonia, a waste byproduct of cell metabolism, and use it as a source of nitrogen to fuel tumor growth, report scientists from Harvard Medical School. The insights shed light on the biological role of ammonia in cancer and may inform the design of new therapeutic strategies to slow tumor growth.
A University of Colorado Cancer Center study published today in the journal ACS Nano describes the use of cutting-edge microscopy technology to visualize how liposomes escape from blood vessels into surrounding cells in a living mouse, offering clues that may help researchers design better drug delivery systems.
Many adults put off discussing end-of-life issues with children, but a UB researcher says the otherwise difficult conversation can begin with the help of Disney/Pixar films.
Blood samples taken by first responders showed that individuals exposed to small amounts of oil from the spill suffered from hemolytic anemia--a condition that occurs when toxins enter the blood stream and damage red blood cells that carry oxygen to tissues.
Modeling the interplay between neurons and astrocytes derived from children with Autism Spectrum Disorder (ASD), researchers at University of California San Diego School of Medicine, with colleagues in Brazil, say innate inflammation in the latter appears to contribute to neuronal dysfunction in at least some forms of the disease.
How do mosquitoes land and take off without our noticing? Using high-speed video cameras, a team from UC Berkeley and Wageningen University have found part of the answer: mosquitoes' long legs allow them to slowly and gently push off, but their wings provide the majority of the lift, even when fully laden with a blood meal. For comparison, mosquitoes push off with forces much less than those of an escaping fruit fly.
Children who are considered to be at risk of developing eye cancer should receive genetic counseling and testing as soon as possible to clarify risk for the disease. This is the consensus of leading ophthalmologists, pathologists and geneticists, who worked for two years to develop the first U.S. guidelines on how to screen for the most common eye tumor affecting children.
Two Medicare 'pay for performance' programs have contributed to declining financial performance by hospitals in the Mississippi Delta region, suggests a study in the November issue of Medical Care, published by Wolters Kluwer.
New findings by a Harvard Medical School team suggest that palbociclib, a drug that is FDA-approved to treat advanced breast cancer, may be able to overcome vemurafenib resistance in PTC.