A national research team led by UC Davis Health clinicians and researchers from the University of Michigan, Nationwide Children's Hospital and Columbia University, has derived and validated a new protocol for emergency departments that can determine which infant patients with fevers, age 60 days or younger, are at low risk of significant bacterial infections.
A new clinical practice guideline from the American Academy of Sleep Medicine (AASM) provides guidance to clinicians on the use of positive airway pressure (PAP) therapy to treat obstructive sleep apnea (OSA) in adults.
A new breakthrough from the Genetic Investigation of Anthropometric Traits consortium, which includes many public health researchers from the University of North Carolina at Chapel Hill, identifies multiple genetic variants associated with how the body regulates and distributes body-fat tissue. The new findings broaden the understanding of how genes can predispose certain individuals to obesity.
Smoking more than 20 cigarettes a day can damage your vision, a study co-authored by a Rutgers researcher finds.
UC San Francisco scientists have used the CRISPR-Cas9 gene-editing system to create the first pluripotent stem cells that are functionally 'invisible' to the immune system, a feat of biological engineering that, in laboratory studies, prevented rejection of stem cell transplants. Because these 'universal' stem cells can be manufactured more efficiently than stem cells tailor-made for each patient -- the individualized approach that dominated earlier efforts -- they bring the promise of regenerative medicine a step closer to reality.
MD Anderson researchers discovered that a combination of immunotherapy and targeted therapies that block normal DNA damage repair, such as PARP inhibitors, achieved dramatic tumor reduction in mouse models of small cell lung cancer.
Despite rapid advances in targeted therapies for cancer, tumors commonly develop resistance to treatment. When resistance emerges, tumor cells continue to grow unchecked, despite all attempts to slow cancer progression. While mutations in cancer cells significantly affect drug sensitivity, it is increasingly recognized that ecological interactions between cells can also play a role. Jacob Scott, M.D., D.Phil., a physician-scientist at Cleveland Clinic, is interested in learning how cancer cells develop and maintain drug resistance from an eco-evolutionary perspective.
Directly activating a gene important to exciting our excitatory neurons and associated with major depression may help turn around classic symptoms like social isolation and loss of interest, at least for males, scientists report.
New research shows us just how important primary care physicians are in prolonging our lives. Every 10 additional primary care physicians per 100,000 people in the United States was associated with a 51.5-day increase in life expectancy during the decade from 2005 to 2015, according to a study led by researchers at the Stanford University School of Medicine and Harvard Medical School.
A Vanderbilt University Medical Center study in the New England Journal of Medicine is showing that using bag-mask ventilation, squeezing air from a bag into the mouth for 60 seconds to help patients' breathing, improves outcomes and could potentially save lives.