Researchers have discovered that the protein ASTN2 shuttles receptors away from the surface of neurons, a process that facilitates efficient brain activity.
A research team led by Arun Iyer, Ph.D., assistant professor of pharmaceutical sciences in the Eugene Applebaum College of Pharmacy and Health Sciences at Wayne State University, has developed a nanoplatform technology that works in combination with existing chemotherapeutic drugs that may reverse drug-resistance in renal cell carcinoma.
In proof-of-concept experiments, University of Alabama at Birmingham researchers have highlighted a potential therapy for a rare but potentially deadly blood-clotting disorder, TTP. The researchers deliver this therapeutic enzyme via the cellular equivalent of a Trojan Horse, using tiny blood cell platelets as their protective delivery vehicle, with a key enzyme hidden inside.
Researchers at Rensselaer Polytechnic Institute--led by Juergen Hahn, professor and head of biomedical engineering--are continuing to make remarkable progress with their research focused on autism spectrum disorder (ASD).
Combating glioblastoma remains a major challenge due the complex nature of these tumors, the inability of drugs to penetrate the brain tissue, and lack of correlation between animal models and the human condition.
A new study using antimicrobial susceptibility testing and whole genome sequencing to test extended spectrum beta lactamase (ESBL) producing E. coli isolated from cattle for food production and from various retail meat products has shown that all were resistant to at least three antimicrobial classes.
New avenues are now being opened for future treatment of Laing distal myopathy, a rare disorder that causes muscles in the feet, hands and elsewhere to atrophy. In a study published in the journal PNAS, researchers have identified an enzyme with a clear link to how the disease develops.
Study shows there is a genetic predisposition to early-onset AFib in blacks and Latinos that is greater than what is observed in whites.
Infants born prematurely face challenges in developing the complex, interrelated skills needed for effective feeding. An assessment called the Early Feeding Skills (EFS) checklist is a valid and reliable tool for evaluating the emergence of feeding skills in preterm infants, reports a study in Advances in Neonatal Care, official journal of the National Association of Neonatal Nurses. The journal is published in the Lippincott portfolio by Wolters Kluwer.
Researchers from Michigan State University College of Human Medicine and physicians from Spectrum Health have identified for the first time in a human patient a genetic disorder only previously described in animal models.