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Showing releases 1-25 out of 1241.

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Public Release: 19-Feb-2017
2017 AAAS Annual Meeting
When screening for disease, risk is as important to consider as benefits, study indicates
University of Virginia statistician Karen Kafadar is developing new techniques for understanding the difference between length of diagnosis and length of life regarding cancer screening.

Contact: Fariss Samarrai
University of Virginia

Public Release: 19-Feb-2017
2017 AAAS Annual Meeting
Bringing evidence to health screening debates
At a talk and panel discussion in Boston the morning of Feb. 19, Brown University biostatistician Constantine Gatsonis will discuss how big trials help us make sense of our many questions about cancer screening.

Contact: David Orenstein
Brown University

Public Release: 17-Feb-2017
2017 AAAS Annual Meeting
Researchers are first to see DNA 'blink'
Northwestern University biomedical engineers have developed imaging technology that is the first to see DNA 'blink,' or fluoresce. The tool enables researchers to study individual biomolecules (DNA, chromatin, proteins) as well as important global patterns of gene expression, which could yield insights into cancer. Vadim Backman will discuss the technology and its applications -- including the new concept of macrogenomics, a technology aiming to regulate the global patterns of gene expression without gene editing -- at the 2017 AAAS annual meeting.

Contact: Megan Fellman
Northwestern University

Public Release: 17-Feb-2017
Journal of Experimental Medicine
Tumor suppressor promotes some acute myeloid leukemias, study reveals
Researchers in Germany have discovered that a tumor suppressor protein thought to prevent acute myeloid leukemia (AML) can actually promote a particularly deadly form of the disease. The study, 'RUNX1 cooperates with FLT3-ITD to induce leukemia,' which will be published online Feb. 17 in The Journal of Experimental Medicine, suggests that targeting this protein could be an effective treatment for certain AML patients.
Deutsche Krebshilfe Foundation, Bundesministerium fur Gesundheit, Freie und Hansestadt Hamburg

Contact: Ben Short
Rockefeller University Press

Public Release: 17-Feb-2017
BMJ Open
Quality of life with those with advanced cancer improved through walking
Walking for just 30 minutes three times per week could improve the quality of life for those with advanced cancer, a new study published in the BMJ Open journal has found.

Contact: Natasha Meredith
University of Surrey

Public Release: 17-Feb-2017
Nature Scientific Reports
Role of rogue protein PAK4 confirmed in pancreatic cancer cells
A new study that confirms the role of a protein called PAK4 in the movement and growth of pancreatic cancer cells could help researchers find new ways to tackle the disease.
Pancreatic Cancer Research Fund

Contact: Beck Lockwood
Pancreatic Cancer Research Fund

Public Release: 16-Feb-2017
Molecular Cell
How cancers trick the immune system into helping rather than harming them
Scientists from Trinity College Dublin have identified a molecule that sends a 'wound-healing' message from tumour cells. If we can disrupt this messaging system, we may be able to fight certain cancers.

Contact: Thomas Deane
Trinity College Dublin

Public Release: 16-Feb-2017
Scientists reveal the treadmilling motion of dividing bacteria
An international team of scientists using the latest imaging techniques have revealed how bacterial division proteins build a partition wall across the cell, one molecule at a time.

Contact: Helen Rae
Newcastle University

Public Release: 16-Feb-2017
Cancer Epidemiology, Biomarkers & Prevention
Site of care may partly explain survival difference between kids and AYAs with leukemia
Adolescents and young adults (AYAs) with acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML) who were not treated at specialized cancer centers had significantly worse five-year survival compared with children with these cancers who were treated at specialized cancer centers, whereas AYAs treated at specialized cancer centers had outcomes comparable to children treated at specialized cancer centers.
National Institutes of Health, St. Baldrick's Foundation

Contact: Lauren Riley
American Association for Cancer Research

Public Release: 16-Feb-2017
Cell Stem Cell
Scientists create novel model that shows progression from normal blood cells to leukemia
Mount Sinai researchers have created a novel model that shows the step-by-step progression from normal blood cells to leukemia and its precursor diseases, creating replicas of the stages of the disease to test the efficacy of therapeutic interventions at each stage, according to a study to be published in Cell Stem Cell. This research marked the first time scientists have been able to transplant leukemia from humans to a test tube and then into mice for study.
NIH/National Heart, Lung, and Blood Institute, NIH/National Institute of Diabetes and Digestive and Kidney Diseases, Damon Runyon Cancer Research Foundation, Edward P. Evans Foundation

Contact: Marlene Naanes
The Mount Sinai Hospital / Mount Sinai School of Medicine

Public Release: 16-Feb-2017
Cancer Cell
Adenoviruses and the immune system join forces against cancer
IDIBELL researchers have developed an oncolytic virus capable of redirecting the patient's immune system against their tumor cells. Their work may lead to the development of new therapeutic strategies for several types of cancer.
Spanish Ministerio de Economía y Competitividad, Generalitat de Catalunya, European Commission

Contact: Gemma Fornons
IDIBELL-Bellvitge Biomedical Research Institute

Public Release: 16-Feb-2017
CA: A Cancer Journal for Clinicians
Report: Clinicians should routinely counsel patients on physical activity
A new study concludes that physical activity should be routinely assessed during every doctor-patient visit.

Contact: David Sampson
American Cancer Society

Public Release: 16-Feb-2017
Nature Communications
Spider web of cancer proteins reveals new drug possibilities
Scientists at Winship Cancer Institute of Emory University have mapped a vast spider web of interactions between proteins in lung cancer cells, as part of an effort to reach what was considered 'undruggable.' This approach revealed new ways to target cells carrying mutations in cancer-causing genes.
NIH/National Cancer Institute, Winship Cancer Institute, Georgia Research Alliance

Contact: Holly Korschun
Emory Health Sciences

Public Release: 16-Feb-2017
JCI Insight
Doctors treat deadly cancerous disorders with gene-guided, targeted therapy
Genomic testing of biopsies from patients with deadly, treatment-resistant cancerous blood syndromes called histiocytoses allowed doctors to identify genes fueling the ailments and use targeted molecular drugs to successfully treat them. Researchers report their data in Journal of Clinical Investigation Insight (JCI Insight). They recommend the regular use of comprehensive genomic profiling at diagnosis to positively impact clinical care.

Contact: Nick Miller
Cincinnati Children's Hospital Medical Center

Public Release: 16-Feb-2017
IEEE Engineering in Medicine and Biology Society (EMBS) flagship conference International Conference
Real-time MRI analysis powered by supercomputers
Researchers from the Texas Advanced Computing Center, The University of Texas Health Science Center and Philips Healthcare have developed a new, automated platform capable of returning in-depth analyses of MRI scans in a matter of minutes, rather than hours or days. The system has the potential to minimize patient callbacks, save millions annually, and advance precision medicine.
National Science Foundation, National Institutes of Health

Contact: Aaron Dubrow
University of Texas at Austin, Texas Advanced Computing Center

Public Release: 16-Feb-2017
Cell Reports
Looking beyond cancer cells to understand what makes breast cancer spread
A new study from researchers at the University of Michigan Comprehensive Cancer Center identifies a protein in that microenvironment that promotes the spread of breast cancer cells. It's part of a well-known family of receptors for which promising inhibitors are being developed.
National Institutes of Health

Contact: Nicole Fawcett
Michigan Medicine - University of Michigan

Public Release: 16-Feb-2017
Targeted radiosurgery better than whole-brain radiation for treating brain tumors
Tumors that originate in other organs of the body and spread to the brain are known as metastatic brain tumors. According to the American Brain Tumor Association, this tumor type is the most common in adults, affecting as many as 300,000 people each year. University of Missouri School of Medicine researchers compared two common postsurgical therapies for metastatic brain tumors and found that stereotactic radiosurgery can provide better outcomes for patients compared to whole-brain radiation.
American Brain Tumor Association, University of Missouri School of Medicine Office of Medical Research

Contact: Derek Thompson
University of Missouri-Columbia

Public Release: 16-Feb-2017
BMC Biology
Targeting the biological clock could slow the progression of cancer
Does the biological clock in cancer cells influence tumour growth? Yes, according to a study conducted by Nicolas Cermakian, a professor in McGill University's Department of Psychiatry.

Contact: Bruno Geoffroy
514-630-2225 x5257
McGill University

Public Release: 15-Feb-2017
Nature Communications
Ottawa researchers kill brain cancer in mice with combination immunotherapies
A combination of drugs known as SMAC Mimetics and immune checkpoint inhibitors (ICIs) amplifies kill rates of cancer tumor cells in laboratory testing.

Contact: Adrienne Vienneau
613-737-7600 x4144
Children's Hospital of Eastern Ontario Research Institute

Public Release: 15-Feb-2017
CSIC develops a biosensor able to detect HIV only one week after infection
A team from the Spanish National Research Council (CSIC) has developed a biosensor that can detect type 1 HIV during the first week after infection. The experiments, performed on human serum, detect the p24 antigen, a protein present in the HIV-1 virus. This new technology, which has been patented by CSIC, detects the protein at concentrations 100,000 times lower than in current techniques.

Contact: Ainhoa Goñi
Spanish National Research Council (CSIC)

Public Release: 15-Feb-2017
Scalp cooling can help some breast cancer patients retain hair
Scalp cooling can lessen some chemotherapy-induced hair loss -- one of the most devastating hallmarks of cancer -- in certain breast cancer patients, according to a new multicenter study from UC San Francisco, Weill Cornell Medicine and three other medical centers.
Lazlo Tauber Family Foundation, Anne Moore Breast Cancer Research Fund, and The Friedman Family Foundation

Contact: Krystle Lopez
Weill Cornell Medicine

Public Release: 15-Feb-2017
Science Translational Medicine
Scientifically-designed fasting diet lowers risks for major diseases
Results of a randomized clinical trial shows a periodic, five-day fasting diet designed by a USC researcher safely reduced the risk factors for heart disease, cancer, diabetes and other age-related diseases.
USC Edna M. Jones Chair in Gerontology fund, National Institutes of Health

Contact: Emily Gersema
University of Southern California

Public Release: 15-Feb-2017
Journal of Thoracic Oncology
Radiotherapy for invasive breast cancer increases the risk of second primary lung cancer
East Asian female breast cancer patients receiving radiotherapy have a higher risk of developing second primary lung cancer.

Contact: Becky Bunn
International Association for the Study of Lung Cancer

Public Release: 15-Feb-2017
More patients with early-stage breast cancer may be able to avoid chemotherapy in the future
Women with early-stage breast cancer who had an intermediate risk recurrence score (RS) from a 21-gene expression assay had similar outcomes, regardless of whether they received chemotherapy, a new study from The University of Texas MD Anderson Cancer finds.

Contact: Laura Sussman
University of Texas M. D. Anderson Cancer Center

Public Release: 15-Feb-2017
Scientists discover how the cells in skin and organ linings maintain constant cell numbers
Research published today in Nature from scientists at Huntsman Cancer Institute (HCI) at the University of Utah shows how epithelial cells naturally turn over, maintaining constant numbers between cell division and cell death.
National Institute of Health, University of Utah, NIH/National Cancer Institute, Huntsman Cancer Foundation

Contact: Tonya Papanikolas
University of Utah Health Sciences

Showing releases 1-25 out of 1241.

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