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Showing releases 1-25 out of 1255.

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Public Release: 21-Feb-2017
Israeli, Palestinian researchers cooperate to find risks for B cell non-hodgkin lymphoma
Most epidemiological studies of Non-Hodgkin's Lymphoma (NHL) have been carried out in North American and European populations, with very few focusing on B-cell NHL in Middle Eastern populations. Now, Israeli and Palestinian researchers have conducted a large scale epidemiological study examining risk factors for B-NHL and its sub-types in the Israeli and Palestinian populations, finding some risk factors common to both groups, and some that are unique to only one population.
MERC/USAID, Israel Science Foundation, Hadassah University Hospital Compensatory Fund

Contact: Dov Smith
The Hebrew University of Jerusalem

Public Release: 21-Feb-2017
Novel breast tomosynthesis technique reduces screening recall rate
A new digital breast tomosynthesis technique has the potential to reduce the rate at which women are called back for additional examinations without sacrificing cancer detection, according to a new study.

Contact: Linda Brooks
Radiological Society of North America

Public Release: 21-Feb-2017
Screening MRI benefits women at average risk of breast cancer
MRI screening improves early diagnosis of breast cancer in all women-not only those at high risk-according to a new study from Germany.

Contact: Linda Brooks
Radiological Society of North America

Public Release: 21-Feb-2017
Nature Communications
Danish discovery opens up for new type of immunological treatment of cancer
Researchers from Aarhus University have found an important piece of the puzzle leading towards an understanding of how our innate immune system reacts against viral infections and recognises foreign DNA, for example from dying cancer cells. The discovery may prove to be of great importance for immunological treatment of cancer as well as autoimmune diseases in the future.
The Lundbeck Foundation, Danish Council for Independent Research, Augustinus Foundation, Frode V. Nyegaard og Hustrus Foundation

Contact: Martin Roelsgaard Jakobsen
Aarhus University

Public Release: 21-Feb-2017
Cancer Epidemiology, Biomarkers & Prevention
Hispanic cancer mortality varies among ethnic groups
Cancer mortality rates vary considerably within the growing Hispanic population in the United States, with significant differences among the major Hispanic ethnic groups.
NIH/National Institute of General Medical Sciences

Contact: Lauren Riley
American Association for Cancer Research

Public Release: 20-Feb-2017
Metabolism drives growth and division of cancer cells
Nobel Prize laureate Otto H. Warburg observed in the 1920s that tumor cells radically change their metabolism. This process, termed 'Warburg Effect,' was neglected until recently by cancer research, but latest results show ist fundamental importance for the development of aggressive tumors. Richard Moriggl from the VetmeduniVienna now published in Leukemia how the tumor promoter STAT5 integrates metabolic signals that contribute to oncogenic transformation and may have thus identified a new target to tackle cancer.

Contact: Richard Moriggl
University of Veterinary Medicine -- Vienna

Public Release: 20-Feb-2017
JAMA Oncology
SWOG study shows strong long-term survival rates for patients with GIST
Researchers show that nearly one in four patients with incurable gastrointestinal stromal tumors (GIST) treated with Gleevec will survive 10 years. Results are published in JAMA Oncology.
NIH/National Cancer Institute, Novartis Pharmaceuticals

Contact: Wendy Lawton

Public Release: 20-Feb-2017
2017 AAAS Annual Meeting
Decision-making suffers when cancer patients avoid math
Many of the toughest decisions faced by cancer patients involve knowing how to use numbers -- calculating risks, evaluating treatment options and figuring odds of medication side effects. But for patients who aren't good at math, decision science research can offer evidence-based advice on how to assess numeric information and ask the right questions to make informed choices.

Contact: Jeff Grabmeier
Ohio State University

Public Release: 20-Feb-2017
Proceedings of the National Academy of Sciences
Pitt study finds potential marker of drug response in many cancer types
Researchers at the University of Pittsburgh School of Medicine have uncovered a novel genetic mechanism of thyroid cancer, as well as a marker that may predict response to a particular class of drugs, not just in patients with thyroid cancer, but in those with many other types of cancer as well.
National Institutes of Health, David and Nancy Brent

Contact: Allison Hydzik
University of Pittsburgh Schools of the Health Sciences

Public Release: 20-Feb-2017
Many cancer survivors change their prescription drug use for financial reasons
A new analysis indicates that many cancer survivors change their prescription drug use (including skipping doses or requesting cheaper medications) for financial reasons.

Contact: Dawn Peters

Public Release: 20-Feb-2017
Journal of Materials Science
New approach for the capture of tumor-derived exosomes from a prostate cancer cell line
In a new paper in Springer's Journal of Materials Science, researchers at Washington State University report a new approach for the effective capture of tumor-derived exosomes from a prostate cancer cell line. Exosomes are small secreted vesicles that play a key role in intercellular communication and cancer progression.
Prostate Cancer Research Program

Contact: Joan Robinson

Public Release: 20-Feb-2017
Scientific Reports
Biomarker predicts poor prognosis in African-Americans with triple-negative breast cancer
Having high levels of a certain biomarker is linked to poor prognosis in African-American patients with triple-negative breast cancer, while the same biomarker doesn't influence disease outcomes in white patients, according to a new study.
NIH/National Cancer Institute, NIH/National Institute on Minority Health and Health Disparities

Contact: LaTina Emerson
Georgia State University

Public Release: 20-Feb-2017
Proceedings of the National Academy of Sciences
Protein once thought exclusive to neurons helps some cancers grow, spread, defy death
How we think and fall in love are controlled by lightning-fast electrochemical signals across synapses, the dynamic spaces between nerve cells. Until now, nobody knew that cancer cells can repurpose tools of neuronal communication to fuel aggressive tumor growth and spread.

Contact: Deborah Wormser
UT Southwestern Medical Center

Public Release: 20-Feb-2017
Journal of Global Oncology
New approach to cervical cancer care in Botswana cuts treatment lag time in half
Cervical cancer is the leading cause of cancer deaths for women low- and middle-income countries, including Botswana, where 75 percent of cervical cancer patients suffer from advanced forms of the disease. These patients can face wait times as long as five months after diagnosis before receiving lifesaving treatment. A new, multidisciplinary model of cervical cancer care developed by a University of Pennsylvania team based in Botswana cut the delay between diagnosis and treatment by more than 50 percent.

Contact: Johanna Harvey
University of Pennsylvania School of Medicine

Public Release: 19-Feb-2017
2017 AAAS Annual Meeting
Bringing evidence to health screening debates
At a talk and panel discussion in Boston the morning of Feb. 19, Brown University biostatistician Constantine Gatsonis will discuss how big trials help us make sense of our many questions about cancer screening.

Contact: David Orenstein
Brown University

Public Release: 19-Feb-2017
2017 AAAS Annual Meeting
When screening for disease, risk is as important to consider as benefits, study indicates
University of Virginia statistician Karen Kafadar is developing new techniques for understanding the difference between length of diagnosis and length of life regarding cancer screening.

Contact: Fariss Samarrai
University of Virginia

Public Release: 17-Feb-2017
Journal of Experimental Medicine
Tumor suppressor promotes some acute myeloid leukemias, study reveals
Researchers in Germany have discovered that a tumor suppressor protein thought to prevent acute myeloid leukemia (AML) can actually promote a particularly deadly form of the disease. The study, 'RUNX1 cooperates with FLT3-ITD to induce leukemia,' which will be published online Feb. 17 in The Journal of Experimental Medicine, suggests that targeting this protein could be an effective treatment for certain AML patients.
Deutsche Krebshilfe Foundation, Bundesministerium fur Gesundheit, Freie und Hansestadt Hamburg

Contact: Ben Short
Rockefeller University Press

Public Release: 17-Feb-2017
2017 AAAS Annual Meeting
Researchers are first to see DNA 'blink'
Northwestern University biomedical engineers have developed imaging technology that is the first to see DNA 'blink,' or fluoresce. The tool enables researchers to study individual biomolecules (DNA, chromatin, proteins) as well as important global patterns of gene expression, which could yield insights into cancer. Vadim Backman will discuss the technology and its applications -- including the new concept of macrogenomics, a technology aiming to regulate the global patterns of gene expression without gene editing -- at the 2017 AAAS annual meeting.

Contact: Megan Fellman
Northwestern University

Public Release: 17-Feb-2017
BMJ Open
Quality of life with those with advanced cancer improved through walking
Walking for just 30 minutes three times per week could improve the quality of life for those with advanced cancer, a new study published in the BMJ Open journal has found.

Contact: Natasha Meredith
University of Surrey

Public Release: 17-Feb-2017
Nature Scientific Reports
Role of rogue protein PAK4 confirmed in pancreatic cancer cells
A new study that confirms the role of a protein called PAK4 in the movement and growth of pancreatic cancer cells could help researchers find new ways to tackle the disease.
Pancreatic Cancer Research Fund

Contact: Beck Lockwood
Pancreatic Cancer Research Fund

Public Release: 16-Feb-2017
BMC Biology
Targeting the biological clock could slow the progression of cancer
Does the biological clock in cancer cells influence tumour growth? Yes, according to a study conducted by Nicolas Cermakian, a professor in McGill University's Department of Psychiatry.

Contact: Bruno Geoffroy
514-630-2225 x5257
McGill University

Public Release: 16-Feb-2017
Targeted radiosurgery better than whole-brain radiation for treating brain tumors
Tumors that originate in other organs of the body and spread to the brain are known as metastatic brain tumors. According to the American Brain Tumor Association, this tumor type is the most common in adults, affecting as many as 300,000 people each year. University of Missouri School of Medicine researchers compared two common postsurgical therapies for metastatic brain tumors and found that stereotactic radiosurgery can provide better outcomes for patients compared to whole-brain radiation.
American Brain Tumor Association, University of Missouri School of Medicine Office of Medical Research

Contact: Derek Thompson
University of Missouri-Columbia

Public Release: 16-Feb-2017
Cell Reports
Looking beyond cancer cells to understand what makes breast cancer spread
A new study from researchers at the University of Michigan Comprehensive Cancer Center identifies a protein in that microenvironment that promotes the spread of breast cancer cells. It's part of a well-known family of receptors for which promising inhibitors are being developed.
National Institutes of Health

Contact: Nicole Fawcett
Michigan Medicine - University of Michigan

Public Release: 16-Feb-2017
Nature Communications
Spider web of cancer proteins reveals new drug possibilities
Scientists at Winship Cancer Institute of Emory University have mapped a vast spider web of interactions between proteins in lung cancer cells, as part of an effort to reach what was considered 'undruggable.' This approach revealed new ways to target cells carrying mutations in cancer-causing genes.
NIH/National Cancer Institute, Winship Cancer Institute, Georgia Research Alliance

Contact: Holly Korschun
Emory Health Sciences

Public Release: 16-Feb-2017
IEEE Engineering in Medicine and Biology Society (EMBS) flagship conference International Conference
Real-time MRI analysis powered by supercomputers
Researchers from the Texas Advanced Computing Center, The University of Texas Health Science Center and Philips Healthcare have developed a new, automated platform capable of returning in-depth analyses of MRI scans in a matter of minutes, rather than hours or days. The system has the potential to minimize patient callbacks, save millions annually, and advance precision medicine.
National Science Foundation, National Institutes of Health

Contact: Aaron Dubrow
University of Texas at Austin, Texas Advanced Computing Center

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