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Key: Meeting M      Journal J      Funder F

Showing releases 1-25 out of 972.

1 | 2 | 3 | 4 | 5 > >>

Public Release: 22-Mar-2018
Trends in Biochemical Sciences
The universal language of hormones
Bioinformatics specialists from the University of Würzburg have studied a specific class of hormones which is relevant for plants, bacteria and indirectly for humans, too. Their results challenge previous scientific assumptions.

Contact: Prof. Dr. Thomas Dandekar
University of Würzburg

Public Release: 22-Mar-2018
Communications Biology
Novel genomics tool enables more accurate identification of rare mutations in cancer cells
A new computational method developed by researchers at the New York Genome Center (NYGC) allows scientists to identify rare gene mutations in cancer cells with greater accuracy and sensitivity than currently available approaches. The technique, reported in today's Communications Biology from Nature Research publishing, is called Lancet and represents a major advance in the identification of tumor cell mutations, a process known as somatic variant calling.

Contact: Karen Zipern
New York Genome Center

Public Release: 22-Mar-2018
LifeTime -- A visionary proposal for an EU Flagship
Reliably predicting the onset and trajectory of a disease might seem like a distant dream. But a European consortium is aiming to achieve exactly this using a set of emerging technologies with the analysis of single cells at their core. Leading scientists have now submitted the proposal for a FET Flagship called LifeTime.
European Commission

Contact: Nikolaus Rajewsky
Max Delbrück Center for Molecular Medicine in the Helmholtz Association

Public Release: 22-Mar-2018
Nature Communications
An integrated workflow for interaction proteomics -- as versatile as the Swiss Army Knife
Researchers of the University of Helsinki, Finland, developed an integrated workflow for interaction proteomics, which -- as they describe it -- proves almost as versatile as the Swiss Army Knife.

Contact: Dr. Markku Varjosalo
University of Helsinki

Public Release: 22-Mar-2018
Cancer Research
Researchers identify compound to prevent breast cancer cells from activating in brain
Researchers at Houston Methodist used computer modeling to find an existing investigational drug compound for leukemia patients to treat triple negative breast cancer once it spreads to the brain.
National Institutes of Health, John S. Dunn Research Foundation

Contact: Gale Smith
Houston Methodist

Public Release: 22-Mar-2018
Long thought to only cause a rare disease, this mutation may ward off malaria
The discovery sheds light on how humans who live in close quarters with malaria-carrying mosquitos may evolve defenses against the disease.
National Institutes of Health, A.P. Giannini postdoctoral fellowship, Pew Biomedical Scholar program

Contact: Madeline McCurry-Schmidt
Scripps Research Institute

Public Release: 21-Mar-2018
Science Advances
Bats can learn from other species, in addition to their own
Not only are bats capable of auditory-based social learning to identify a new food source from individuals in their own species, but they can also learn about new food sources just as quickly from members of a different species, a new study finds. These results suggest that bats may learn from different species in nature and offer further insights into the adaptive strategies and evolution of bats.

Contact: Krista J. Patriquin
American Association for the Advancement of Science

Public Release: 20-Mar-2018
Optics Letters
Researchers create microlaser that flies along hollow optical fiber
For the first time, researchers have optically trapped and propelled a particle-based laser for centimeters inside an optical fiber.

Contact: Joshua Miller
The Optical Society

Public Release: 20-Mar-2018
Sound new technique tunes into the shifting shapes of biology
Scientists at the John Innes Centre have come up with a novel way of quantifying cell shapes -- with a lot of mathematics and a little musical inspiration.

Contact: Adrian Galvin
John Innes Centre

Public Release: 19-Mar-2018
Nature Biotechnology
UC Santa Cruz research signals arrival of a complete human genome
Research from a UC Santa Cruz Genomics Institute-affiliated team just published in the journal Nature Biotechnology attempts to close huge gaps remain in our genomic reference map. The research uses nanopore long-read sequencing to generate the first complete and accurate linear map of a human Y chromosome centromere. This milestone in human genetics and genomics signals that scientists are finally entering a technological phase when completing the human genome will be a reality.
NIH/National Human Genome Research Institute, The Keck Foundation

Contact: Alexis Morgan
University of California - Santa Cruz

Public Release: 19-Mar-2018
Nature Methods
Deeper insight into viral infections
Würzburg researchers have developed a new analysis technique that sheds more light on viral infections. They used the new method to demonstrate that virus-infected cells produce far more infection-related proteins and peptides than previously thought.
MRC Clinical Fellowship, NHSBT grant, European Research Council grant, Wellcome Trust Senior Clinical Research Fellowship, German Research Foundation DFG, Free State of Bavaria BioSysNet

Contact: Lars Dölken
University of Würzburg

Public Release: 19-Mar-2018
Nature Biotechnology
A reference catalog for the rumen microbiome
In Nature Biotechnology, an international team including scientists at the US Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility, present a reference catalog of rumen microbial genomes and isolates cultivated and sequenced from the Hungate1000 collection. One of the largest targeted cultivation and sequencing projects to date, the collection was produced through the coordinated efforts of rumen microbiology researchers worldwide.
US Department of Energy Office of Science

Contact: David Gilbert
DOE/Lawrence Berkeley National Laboratory

Public Release: 19-Mar-2018
Commonly used drugs affect our gut bacteria
One in four drugs with human targets inhibit the growth of bacteria in the human gut. These drugs cause antibiotic-like side-effects and may promote antibiotic resistance, EMBL researchers report in Nature on March 19.

Contact: Iris Kruijen
European Molecular Biology Laboratory

Public Release: 16-Mar-2018
With new 'shuffling' trick, researchers can measure gene activity in single cells
Researchers at the University of Washington and the Allen Institute for Brain Science have developed a new method to classify and track the multitude of cells in a tissue sample. In a paper published March 15 in the journal Science, the team reports that this new approach -- known as SPLiT-seq -- reliably tracks gene activity in a tissue down to the level of single cells.
National Institutes of Health, National Science Foundation, Allen Institute for Brain Science

Contact: James Urton
University of Washington

Public Release: 16-Mar-2018
Elusive venomous mammal joins the genome club
An article published in GigaScience presents a draft genome of a small shrew-like animal, the venomous Hispaniolan solenodon. This unusual animal is one of the only extant venomous mammals, and it is the sole remaining branch of mammals that split from other insectivores at the time of the dinosaurs. The solenodon genome sequence revealed the answer to several evolutionary questions, such as whether the solenodon species indeed survived the meteor impact that killed the dinosaurs.
Saint Petersburg State University

Contact: Scott Edmunds

Public Release: 15-Mar-2018
Nature Communications
Democratizing science: Making neuroscience experiments easier to share, reproduce
In a paper published online March 5 in Nature Communications, University of Washington researchers unveiled an open-access browser to display, analyze and share neurological data collected through a type of magnetic resonance imaging study known as diffusion-weighted MRI.
Gordon and Betty Moore Foundation, Alfred P. Sloan Foundation, US Department of Energy

Contact: James Urton
University of Washington

Public Release: 15-Mar-2018
Potential new way to limit antibiotic resistance spreading
One of the biggest current threats to global health is the rise of multi-drug resistant bacteria, caused by the spreading of antibiotic resistance amongst them. In an attempt to help fight this threat, EMBL researchers have unraveled the molecular basis of a major antibiotic resistance transfer mechanism. They also developed molecules and a proof-of-principle for blocking this transfer. Cell publishes their results on March 15.

Contact: Iris Kruijen
European Molecular Biology Laboratory

Public Release: 14-Mar-2018
Chromatin usage in individual cells reveals developmental trajectories
Both cell type and developmental stage can be deduced from measurements of chromatin accessibility in thousands of single cells, researchers at EMBL and the University of Washington show. They used this approach to uncover how cells in developing embryos regulate their identity as they decide what kind of cell to become. Nature publishes the results on March 14.

Contact: Iris Kruijen
European Molecular Biology Laboratory

Public Release: 13-Mar-2018
What do spacecraft, newborns and endangered shellfish have in common?
Researchers at University of California San Diego School of Medicine have developed a microbial detection technique so sensitive that it allows them to detect as few as 50-100 bacterial cells present on a surface. What's more, they can test samples more efficiently -- up to hundreds of samples in a single day.
UC San Diego Chancellor's Microbiome and Microbial Sciences Initiative and Alfred P. Sloan Foundation.

Contact: Heather Buschman
University of California - San Diego

Public Release: 13-Mar-2018
Analytical Chemistry
Prevent antibiotic resistances from spreading: Rapid test helps administering the 'correct' drug
Multi-resistant microbes are a growing danger. The often unnecessary and mass use of antibiotics causes the impassivity of pathogens against drugs. Infections that were easily curable up to now, may become life threatening. A new rapid test will give information on which available antibiotic is still effective. Faster diagnostics allow a personalized therapy and saves lives. A requirement for prevention of spreading antibiotic resistances is a targeted, economical and responsible application of broad-spectrum and last resort antibiotics.
European Union, German Federal Ministry for Education and Research, Free State of Thuringia, Carl-Zeiss-Foundation

Contact: Dr. Ute Neugebauer
Leibniz-Institute of Photonic Technology

Public Release: 13-Mar-2018
Systems Biology and Applications
Researchers computationally find the needle in a haystack to treat rare diseases
One in 10 people in America is fighting a rare disease, or a disorder that affects fewer than 200,000 Americans. Researchers have developed a sophisticated and systematic way to identify existing drugs that can be repositioned to treat a rare disease or condition.
NIH/National Institute of General Medical Sciences

Contact: Alison Satake
Louisiana State University

Public Release: 12-Mar-2018
Nucleic Acids Research
A game changer: Metagenomic clustering powered by supercomputers
Berkeley Lab and Joint Genome Institute researchers took one of the most popular clustering approaches in modern biology -- Markov Clustering algorithm -- and modified it to run efficiently and at scale on supercomputers. Their algorithm achieved a previously impossible feat: clustering a 70 million node and 68 billion edge biological network in hours.

Contact: Linda Vu
DOE/Lawrence Berkeley National Laboratory

Public Release: 12-Mar-2018
A robust method to study cancer heterogeneity in liquid biopsy
Scientists reported the development of a robust procedure for whole-genome copy number profiling of circulating tumor cells (CTCs) from a blood test. In contrast to existing methods that are complex and costly, the single-tube, single-step protocol detect absolute copy number alterations (CNA) in single cells and maintain accuracy at a lower cost than conventional genomic analysis procedure, opening up to the possibility for genome-driven targeted therapy selection and monitoring of disease progression in liquid biopsy.
CANCER-ID, Menarini Silicon Biosystems

Contact: Elena Bevilacqua
Menarini Silicon Biosystems

Public Release: 12-Mar-2018
Nightingale to accelerate personalized medicine by analyzing 40,000 blood samples
Nightingale Health, the Finnish innovator of an internationally recognized biomarker testing technology for chronic disease screening, will analyze 40,000 blood samples from Finland's largest biobank, THL Biobank, acting under the National Institute for Health and Welfare.

Contact: Teemu Suna
Nightingale Health

Public Release: 9-Mar-2018
Nature Medicine
Researcher creates 'Instagram' of immune system, blending science, technology
Hollings Cancer Center researcher Carsten Krieg, Ph.D., who recently joined the faculty of the Medical University of South Carolina, uses a machine aptly labeled Helios to create a sort of 'Instagram' of a person's immune system. Krieg's work was recently published in Nature Medicine, looking at the prediction of response to immunotherapy in melanoma patients.

Contact: Dawn Brazell
Medical University of South Carolina

Showing releases 1-25 out of 972.

1 | 2 | 3 | 4 | 5 > >>