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Key: Meeting M      Journal J      Funder F

Showing releases 1-25 out of 924.

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Public Release: 8-Dec-2016
Queen's researchers receive funding to track impact of climate change on polar bears
Queen's University researchers Stephen C. Lougheed, Peter Van Coeverden de Groot and Graham Whitelaw have been awarded $9.5 million in total partner cash and in-kind contributions -- including $2.4 million from Genome Canada's Large-Scale Applied Research Project competition -- to monitor impacts of environmental change on polar bears. The project, entitled BEARWATCH, will combine leading-edge genomics and Indigenous traditional ecological knowledge (TEK) to develop a non-invasive means of tracking polar bear response to climate change.
Genome Canada

Contact: Chris Armes
chris.armes@queensu.ca
613-533-6000 x77513
Queen's University

Public Release: 8-Dec-2016
JCI Insight
Scientists unlock genetic code of diseased lung cells to find new treatments for IPF
Researchers cracked the complete genetic code of individual cells in healthy and diseased human lung tissues to find potential new molecular targets for diagnosing and treating the lethal lung disease Idiopathic Pulmonary Fibrosis (IPF). A team of scientists from Cincinnati Children's Hospital Medical Center, in collaboration with investigators at Cedars-Sinai Medical Center in Los Angeles, publish their findings Dec. 8 in the Journal of Clinical Investigation Insights (JCI Insights).

Contact: Nick Miller
nicholas.miller@cchmc.org
513-803-6035
Cincinnati Children's Hospital Medical Center

Public Release: 8-Dec-2016
Genome Biology
Tracking breast cancer cell genetics reveals longer potential treatment window
Breast cancer cells break away and spread to other parts of the body relatively late on in breast tumor development, an international team of scientists has shown. The research, jointly led by Dr. Peter Van Loo at the Francis Crick Institute, could help refine cancer therapy and is published in the journal Genome Biology.
K G Jebsen Centre for Breast Cancer Research in Norway, Research Council of Norway, Norwegian Cancer Society, South-Eastern Norway Regional Health Authority, Research Foundation - Flanders, Foundation against Cancer in Belgium, KU Leuven

Contact: Francis Crick Institute Press Office
press@crick.ac.uk
44-203-796-3095
The Francis Crick Institute

Public Release: 7-Dec-2016
International Union of Crystallography Journal
Why keep the raw data?
The increasingly popular subject of raw diffraction data deposition is examined in a Topical Review in IUCrJ.

Contact: Dr. Jonathan K. Agbenyega
ja@iucr.org
01-244-342-878
International Union of Crystallography

Public Release: 7-Dec-2016
Proceedings of the National Academy of Sciences
Molecular switches researched in detail
Seeing, smelling, tasting, regulation of blood pressure -- molecular switches are involved in all of these processes. The mechanism with which these proteins are switched off has been analyzed by a research team at Ruhr-Universität Bochum (RUB), headed by Prof. Dr. Klaus Gerwert and private lecturer Dr Carsten Kötting. With the aid of infrared spectroscopy (FTIR) and computer simulations, they described the process at the subatomic level.
The German Research Foundation

Contact: Carsten Kötting
carsten.koetting@rub.de
49-234-322-4873
Ruhr-University Bochum

Public Release: 7-Dec-2016
Genome Research
Atlas of the RNA universe takes shape
In the last few years, small snippets of RNA, which may have played a key role in the planet's earliest flickering of life, have been uncovered and examined in great detail. Their discovery, first in the tiny soil-dwelling nematode worm C. elegans and shortly thereafter, across the web of life, marks a revolution in biology, with broad implications in the fight against nearly every known disease.

Contact: Richard Harth
RICHARD.HARTH@ASU.EDU
504-427-2666
Arizona State University

Public Release: 6-Dec-2016
Cannabis and Cannabinoid Research
Do cannabis users think package warnings are needed?
Legalization of cannabis for medical or leisure use is increasing in the US, and many experts and cannabis users alike agree that package warnings stating the health risks are needed. The warnings suggested by cannabis users are not necessarily the same as those of medical experts though, as shown in a new study published in Cannabis and Cannabinoid Research.

Contact: Kathryn Ryan
kbrennan@liebertpub.com
914-740-2100
Mary Ann Liebert, Inc./Genetic Engineering News

Public Release: 6-Dec-2016
Scientific Reports
Critical genes unravelled to understand human diseases and support drug discovery
A network analysis of proteins that are most important in responding to environmental signals highlights potential targets for drugs and provides better information on the genetic basis of diseases.

Contact: Hayley London
hayley.london@earlham.ac.uk
07-760-438-218
Earlham Institute

Public Release: 6-Dec-2016
Aging
GeroScope -- a computer method to beat aging
It takes decades of work and millions of dollars to develop new anti-ageing drugs. Computer modeling techniques may significantly reduce the time and cost of development. Scientists have devepoled a GeroScope algorithm to identify geroprotectors -- substances that extend healthy life. GeroScope is able to compare changes in the cells of young and old patients and search for drugs with minimal side effects. The ability to simulate biological effects with a high level of accuracy in silico is a real breakthrough.
Life Extension Foundation, Nvidia Corporation

Contact: Asya Shepunova
shepunova@phystech.edu
7-916-813-0267
Moscow Institute of Physics and Technology

Public Release: 5-Dec-2016
CSU to provide bioprocessing expertise for Department of Defense
Facilities that manufacture biologic drugs like vaccines are a critical part of the nation's biodefense infrastructure. Possible breaches of data systems controlling these biomanufacturing supply chains call for an assessment of their vulnerability to cyberattacks. Colorado State University's Jean Peccoud is part of a multi-institutional team newly commissioned to analyze the security of the nation's biomanufacturing infrastructure.
Department of Defense

Contact: Anne Manning
anne.manning@colostate.edu
970-491-7099
Colorado State University

Public Release: 5-Dec-2016
Nature Chemical Biology
Small but mighty: Tiny proteins with big roles in biology
Salk scientists discover a small protein important for cellular housekeeping.

Contact: Salk Communications
press@salk.edu
858-453-4100
Salk Institute

Public Release: 5-Dec-2016
Biodiversity Data Journal
Efficiency of insect biodiversity monitoring via Malaise trap samples and DNA barcoding
An international team of scientists evaluated the performance of DNA barcoding and the barcode reference library applied to large-scale Malaise trap samples from two German sites over the span of one summer. The scientists conclude that such approaches could help in providing crucial knowledge of the insect biodiversity and its dynamics, as well as enable more efficient management of a habitat's inventory. Their findings are published in the open access Biodiversity Data Journal.

Contact: Dr Matthias F. Geiger
m.geiger@zfmk.de
Pensoft Publishers

Public Release: 5-Dec-2016
Bioinformatics
Rapid validation for genome assemblies? Introducing KAT: K-mer Analysis Toolkit
A new bioinformatics tool has been released by the Earlham Institute that provides rapid validation for whole genome sequencing data as well as genome assemblies produced from Next Generation Sequencing (NGS) data.

Contact: Hayley London
hayley.london@tgac.ac.uk
160-345-0107
Earlham Institute

Public Release: 5-Dec-2016
Nature Communications
Wise plant analysis
Weizmann Institute's WeizMass and MatchWeiz help identify plant metabolites.

Contact: yael edelman
yael.edelman@weizmann.ac.il
Weizmann Institute of Science

Public Release: 5-Dec-2016
Novel genetic tools for bioassessment of European aquatic ecosystems, COST grant proposal
Aquatic ecosystems of our 'blue planet' are severely impacted by pollution and exploitation. Thus there is an urgent need for conservation actions in order to protect and preserve them. This is why monitoring and bioassessment are crucial. The new DNAqua-Net COST Action, funded by the European Union is set to develop new genetic tools for bioassessment and monitoring of aquatic ecosystems. The grant proposal is published in the open-access journal Research Ideas and Outcomes.
European Union

Contact: Florian Leese
florian.leese@uni-due.de
Pensoft Publishers

Public Release: 2-Dec-2016
Nature Reviews Drug Discovery
Map of drugs reveals uncharted waters in search for new treatments
Scientists have created a map of all 1,578 licensed drugs and their mechanisms of action -- as a means of identifying 'uncharted waters' in the search for future treatments. Their analysis of drugs licensed through the Food and Drug Administration reveals that 667 separate proteins in the human body have had drugs developed against them -- just an estimated 3.5 percent of the 20,000 human proteins.
The Institute of Cancer Research London

Contact: Claire Hastings
chastings@icr.ac.uk
020-715-35380
Institute of Cancer Research

Public Release: 1-Dec-2016
Cell Systems
New computational model provides a tool for improving the production of valuable drugs
The model allows scientists to make comprehensive simulations without doing tedious experiments in the laboratory. Hence, the model will tell the scientist, which metabolic pathways are involved in the production of a specific drug, and which growth conditions will presumably give the optimized production potential. This will allow researchers to design better CHO cells optimized for production of therapeutic proteins, which could result in lower prices and greater availability of many drugs.
Novo Nordisk Foundation

Contact: Nathan Lewis
n4lewis@ucsd.edu
Technical University of Denmark

Public Release: 1-Dec-2016
Cancer Letters
The first analysis of Ewing's sarcoma methyloma opens doors to new treatments
IDIBELL researchers describe the Ewing's sarcoma (ES) methylation profile for the first time. The methylation profile unveils the potential of the PTRF gene as a prognostic marker of the disease. The reestablishment of PTRF expression could serve as a therapeutic option in the future.
Carlos III Institute of Health, Asociación Española contra el Cáncer, Fundación Alba Pérez

Contact: Gemma Fornons
gfornons@idibell.cat
0034-638-685-074
IDIBELL-Bellvitge Biomedical Research Institute

Public Release: 30-Nov-2016
Information Sciences
Overlooked elements of language and literature play a key role
Everything is pointing towards success in unravelling the mysteries inherent in every human language, which for nearly 100 years have been an object of intrigue for mathematicians and linguists working on studies into statistics of literature. New analysis of the frequencies of word occurrence in the most famous works of literature, undertaken at the Institute of Nuclear Physics of the Polish Academy of Sciences in Krakow, have shown that our languages are structurally more complex and more exhaustive than they ever before seemed.

Contact: Prof. Stanislaw Drozdz
stanislaw.drozdz@ifj.edu.pl
48-126-628-220
The Henryk Niewodniczanski Institute of Nuclear Physics Polish Academy of Sciences

Public Release: 29-Nov-2016
Nucleic Acids Research
EDGE bioinformatics brings genomics to everyone
A new bioinformatics platform called Empowering the Development of Genomics Expertise (EDGE) will help democratize the genomics revolution by allowing users with limited bioinformatics expertise to quickly analyze and interpret genomic sequence data.

Contact: Nick Njegomir
njegomir@lanl.gov
505-665-9394
DOE/Los Alamos National Laboratory

Public Release: 29-Nov-2016
Genome Research
A surprizing finding shines new light on the largest group of human proteins
The study is the largest to map DNA binding sites and protein-protein interactions for C2H2-ZF proteins, the most abundant human proteins.
Canadian Institutes of Health Research, Canadian Institute for Advanced Research

Contact: Jovana Drinjakovic
jovana.drinjakovic@gmail.com
416-543-7820
University of Toronto

Public Release: 29-Nov-2016
Nature Methods
Omnipath sends strong signal
Omnipath unifies 27 data resources on biological pathways, helping scientists better understand interactions between signalling proteins. Published in Nature Methods, the Omnipath data resource and Pypath software offer an unprecedentedly clear view on signalling pathways in living systems.

Contact: Hayley London
hayley.london@earlham.ac.uk
01-603-450-107
Earlham Institute

Public Release: 29-Nov-2016
Nature Biotechnology
Digital microbes for munching yourself healthy
A research team at the Luxembourg Centre for Systems Biomedicine (LCSB) of the University of Luxembourg has taken an important step in modelling the complexity of the human gut's bacterial communities -- the microbiome -- on the computer. The researchers gathered all known data on the metabolism of 773 bacterial strains -- more than ever before. Working from this data, they developed a computer model for each bacterial strain.
Luxembourg National Research Fund, US Department of Energy

Contact: Thomas Klein
thomas.klein@uni.lu
352-466-644-5148
University of Luxembourg

Public Release: 28-Nov-2016
Nature Communications
Secret phenotypes: Disease devils in invisible details
The human eye often falls short in the hunt for faint genetic drivers that raise the risk of devastating neurological diseases such as autism and schizophrenia. But little eludes a microscope optic attached to a computer, and algorithms that can relate previously hidden phenotypes to subtle genetic mutations.
National Institutes of Health

Contact: Ben Brumfield
ben.brumfield@comm.gatech.edu
404-660-1408
Georgia Institute of Technology

Public Release: 25-Nov-2016
Cell Systems
Enough is enough -- stem cell factor Nanog knows when to slow down
The transcription factor Nanog plays a crucial role in the self-renewal of embryonic stem cells. Previously unclear was how its protein abundance is regulated in the cells. Researchers at the Helmholtz Zentrum München and the Technical University of Munich, working in collaboration with colleagues from ETH Zürich, now report in Cell Systems that the more Nanog there is on hand, the less reproduction there is.

Contact: Dr. Carsten Marr
carsten.marr@helmholtz-muenchen.de
49-893-187-2158
Helmholtz Zentrum München - German Research Center for Environmental Health

Showing releases 1-25 out of 924.

1 | 2 | 3 | 4 | 5 > >>