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Key: Meeting M      Journal J      Funder F

Showing releases 176-200 out of 966.

<< < 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 > >>

Public Release: 14-Aug-2017
Cancer Cell
From cancer evolution to personalized therapies
Being able to predict the resistance or sensitivity of a tumor cell to a drug is a key success-factor of cancer precision therapy. But such a prediction is made difficult by the fact that genetic alterations in tumors change dynamically over time and are often interdependent, following a pattern that is poorly understood.

Contact: Giovanni Ciriello
giovanni.ciriello@sib.swiss
41-216-925-450
Swiss Institute of Bioinformatics

Public Release: 14-Aug-2017
Cancer Cell
Blood biopsy test reads platelets to detect human lung cancer
Researchers in the Netherlands have designed a different approach to the liquid biopsy. Rather than looking for evidence of cancer DNA or other biomarkers in the blood, their test (called thromboSeq) could diagnose non-small cell lung cancer with close to 90 percent accuracy by detecting tumor RNA absorbed by circulating platelets, also known as thrombocytes. Non-small cell lung cancers make up the majority of lung cancer cases. The research appears Aug. 14 in Cancer Cell.

Contact: Joseph Caputo
jcaputo@cell.com
617-335-6270
Cell Press

Public Release: 10-Aug-2017
Nature Communications
Innovations enhance genetic analysis of individual cells
Single cell genomics technology has given scientists the ability to individually read the genetic blueprints of cells, the most fundamental units of life. Now, the center that pioneered the technology, Bigelow Laboratory's Single Cell Genomics Center, has developed several key enhancements to the technology and published them in Nature Communications.

Contact: Steven Profaizer
sprofaizer@bigelow.org
207-315-2567 x103
Bigelow Laboratory for Ocean Sciences

Public Release: 10-Aug-2017
Science
Circular RNA linked to brain function
For the first time, scientists have shown that circular RNA is linked to brain function. When a RNA molecule called Cdr1as was deleted from the genome of mice, the animals had problems filtering out unnecessary information -- like patients suffering from neuropsychiatric disorders.

Contact: Annette Tuffs
Annette.Tuffs@mdc-berlin.de
49-309-406-2140
Max Delbrück Center for Molecular Medicine in the Helmholtz Association

Public Release: 9-Aug-2017
Nature Biotechnology
Defining standards for genomes from uncultivated microorganisms
As genomic data production has ramped up over the past two decades and is being generated on various platforms around the world, scientists have worked together to establish definitions for terms and data collection standards that apply across the board. In Nature Biotechnology, an international team led by DOE JGI researchers has developed standards for the minimum metadata to be supplied with single amplified genomes and metagenome-assembled genomes submitted to public databases.
DOE/Office of Science

Contact: David Gilbert
degilbert@lbl.gov
DOE/Joint Genome Institute

Public Release: 8-Aug-2017
2017 International Tropical Agriculture Conference
The mystery of the yellowing sugarcane
Since 2011, a mysterious illness known as Yellow Canopy Syndrome (YCS) has afflicted Australian sugarcane causing $40 million in losses. Researchers from The University of Texas at Tyler and Sugar Research Australia used supercomputers at the Texas Advanced Computing Center to perform large-scale investigations of the sugarcane genome. They detected signals in the data that could indicate a bacteria or stress causing YCS. They are conducting further computational studies to test their hypotheses.
Sugar Research Australia, National Science Foundation

Contact: Aaron Dubrow
aarondubrow@tacc.utexas.edu
512-470-9453
University of Texas at Austin, Texas Advanced Computing Center

Public Release: 8-Aug-2017
Proceedings of the National Academy of Sciences
New ultrafast method for determining antibiotic resistance
Researchers at Uppsala University have developed a new method for very rapidly determining whether infection-causing bacteria are resistant or susceptible to antibiotics. The findings have now been published in the US journal Proceedings of the National Academy of Sciences (PNAS).
Swedish Research Council, Knut and Alice Wallenberg Foundation

Contact: Johan Elf
Johan.Elf@icm.uu.se
46-070-980-3135
Uppsala University

Public Release: 8-Aug-2017
Journal of Biological Chemistry
Relieving antibiotic resistance: Researchers take steps toward new treatment for E. coli
By understanding the functional differences between proteins expressed by two E. coli strains, researchers at Kansas State University are exploring new opportunities to inhibit their impacts to human health.
National Institutes of Health

Contact: Philip Hardwidge
philiphardwidge@k-state.edu
785-532-2506
Kansas State University

Public Release: 8-Aug-2017
Scientific Reports
A taste cell encyclopedia
A significant technological advance from the Monell Center now allows scientists to identify the complete set of genes in any type of taste receptor cell. The technology provides taste researchers with a treasure trove of information that will help identify precisely how each type of taste receptor cell carries out its specific function.
NIH/National Institute on Deafness and Other Communication Disorders

Contact: Leslie Stein
stein@monell.org
267-519-4707
Monell Chemical Senses Center

Public Release: 7-Aug-2017
New tumor database deployed to battle childhood Cancer at UC Santa Cruz
The Treehouse Childhood Cancer Initiative researchers at UC Santa Cruz Genomics Institute and the St. Baldrick's Foundation are making a 11,000+ tumor database available for use by all researchers in the pediatric cancer community and beyond in our continued battle to take childhood back from cancer. The database contains RNA-Seq gene expression data, as well as age, disease, and sex.
St. Baldrick's Foundation

Contact: Alexis Morgan
amorgan1@ucsc.edu
831-515-8142
University of California - Santa Cruz

Public Release: 7-Aug-2017
Nature
NCI study identifies essential genes for cancer immunotherapy
A new study identifies genes that are necessary in cancer cells for immunotherapy to work, addressing the problem of why some tumors don't respond to immunotherapy or respond initially but then stop as tumor cells develop resistance to immunotherapy.
NIH/National Cancer Institute, NIH/National Human Genome Research Institute

Contact: NCI Press Officers
NCIPressOfficers@mail.nih.gov
301-496-6641
NIH/National Cancer Institute

Public Release: 7-Aug-2017
Nature Genetics
Big data yields surprising connections between diseases
Using health insurance claims data from more than 480,000 people in nearly 130,000 families, researchers at the University of Chicago have created a new classification of common diseases based on how often they occur among genetically-related individuals.
National Institutes of Health, Defense Advanced Research Projects Agency, Liz and Kent Dauten

Contact: Matt Wood
Matthew.Wood@uchospitals.edu
University of Chicago Medical Center

Public Release: 3-Aug-2017
Nature Communications
New botulinum neurotoxin discovered -- potential to treat a number of medical conditions
The first new botulinum neurotoxin in almost half a century has been discovered by researchers at Stockholm University and Harvard Medical School. Botulinum toxins are widely used to treat a growing list of medical conditions. The article has been published in Nature Communications.

Contact: Annika Hallman
press@su.se
Stockholm University

Public Release: 3-Aug-2017
PLOS Biology
Scientists link biodiversity genomics with museum wisdom through new public database
A new publicly available database will catalog metadata associated with biologic samples, making it easier for researchers to share and reuse genetic data for environmental and ecological analyses. It links publicly available genetic data to records of where and when samples were collected. Such information is critical for comparing biodiversity in different locations worldwide, across time. Despite calls for more data sharing within the research community, researchers have until now lacked the tools they needed.
National Science Foundation, Gordon and Betty Moore Foundation, National Oceanic and Atmospheric Administration

Contact: Ryan Lavery
laveryr@si.edu
202-633-0826
Smithsonian

Public Release: 3-Aug-2017
PLOS Computational Biology
New method for organ transplant monitoring promises better care for patients
Using a combination of DNA sequencing and computer science techniques, a team of researchers has developed a new method for monitoring the health of organ transplant patients -- one that promises to provide life-saving clues to diagnose organ rejection at an early stage.

Contact: PLOS Computational Biology
ploscompbiol@plos.org
PLOS

Public Release: 2-Aug-2017
ACS Sensors
Lighting the way: Sensors show drug uptake
When designing and characterizing new drugs, a key aspect is making sure the drug actually goes where it is intended to. But current tests for drug uptake monitor the process under unrealistic conditions and do not provide information on the amounts of drugs that cross into a cell. Now, one group reports in ACS Sensors that fluorescent detector proteins can overcome these challenges.

Contact: Katie Cottingham
k_cottingham@acs.org
301-775-8455
American Chemical Society

Public Release: 1-Aug-2017
Cell Reports
Noise helps cells make decisions
Random differences between cells could be the key to making different types of cells, according to new research. Different cell types all have their own roles, yet they all start out the same. For us to be healthy our bodies need the right number of each cell type. This latest research reveals that when cells specialize into cell types their genes become 'noisy' with slight differences in gene activity affecting what cells become.
Wellcome Trust Strategic Award, BBSRC, Wellcome Trust, KU Leuven

Contact: Jonathan Lawson
jonathan.lawson@babraham.ac.uk
01-223-496-230
Babraham Institute

Public Release: 31-Jul-2017
Nature Methods
New genomics tool CITE-Seq enables large-scale multidimensional analysis of single cells
A new technique developed by scientists at the New York Genome Center (NYGC) represents an important step forward for single-cell RNA sequencing, an advancing field of genomics that provides detailed insights into individual cells and makes it possible to distinguish between different cell types and to study disease mechanisms at the level of individual cells.

Contact: Karen Zipern
kzipern@nygenome.org
646-977-7065
New York Genome Center

Public Release: 31-Jul-2017
Phytobiomes
New and novel technologies successfully demonstrated in soilborne disease study
Soil profiling is a powerful tool used in researching sudden death syndrome of soybean. In a new Phytobiomes journal article, titled 'Unraveling Microbial and Edaphic Factors Affecting the Development of Sudden Death Syndrome in Soybean,' Srour, et al. demonstrate, for the first time, the latest technologies to detect and profile microbial populations in 'diseased' and 'healthy' soils and to correlate their presence with the incidence and severity of SDS.

Contact: Phil Bogdan
pbogdan@scisoc.org
651-994-3859
American Phytopathological Society

Public Release: 31-Jul-2017
Scientific Reports
Scientists challenge next-generation sequencing dogma
Next-generation sequencing -- the ability to sequence millions or billions of small fragments of DNA in parallel -- has revolutionized the biological sciences, playing an essential role in everything from locating mutations that cause human disease to determining how a newly discovered animal fits into the tree of life. But a study published today in the journal Scientific Reports reveals that a favored sequencing method for measuring microbial biodiversity is not as accurate as once thought.
Korein Foundation, Gerstner Family Foundation, Irma T. Hirschl and Minque Weill-Caulier Charitable Trusts, Bert L. and N. Kuggie Vallee Foundation, WorldQuant Foundation, Bill and Melinda Gates Foundation

Contact: Kendra Snyder
ksnyder@amnh.org
212-496-3419
American Museum of Natural History

Public Release: 27-Jul-2017
Nature Communications
The 16 genetic markers that can cut a life story short
Researchers have identified 16 genetic markers associated with a decreased lifespan, including 14 new to science. This is the largest set of markers of lifespan uncovered to date. Spearheaded by scientists from the SIB Swiss Institute of Bioinformatics and other Swiss institutions the study provides a powerful computational framework to uncover the genetics of our time of death, and ultimately of any disease. The study is published today in Nature Communications.

Contact: Marie Dangles
marie.dangles@sib.swiss
41-216-924-075
Swiss Institute of Bioinformatics

Public Release: 27-Jul-2017
Nature
The Danish reference genome
After close to 5 years of work, the GenomeDenmark consortium has now finalized the efforts to establish a Danish Reference genome. The result is a reference of unrivalled quality and information depth, as compared to other similar international references and studies. Due to the unique and high quality approach, the consortium consisting of three Danish universities and the genomics company BGI Europe has been able to analyze otherwise intractable genomics regions for the first time.

Contact: Søren Brunak
brunak@cbs.dtu.dk
45-20-67-24-77
University of Copenhagen The Faculty of Health and Medical Sciences

Public Release: 27-Jul-2017
Cell
Errors made by 'DNA spellchecker' revealed as important cause of cancer
CRG scientists identify important processes that create mutations that cause cancer by studying the genomes of more than 1,000 tumors. Many mutations in human cancers are caused by mistakes made by a repair mechanism or 'DNA spellchecker' rather than the actual damage to DNA caused by the environment. Sunlight and alcohol consumption increase the rate at which this happens, resulting in more mutations in the most important parts of our genomes.
European Research Council, European Commission, AXA Research Fund, Ministerio de Economia Industria y Competitividad

Contact: Laia Cendrós
laia.cendros@crg.eu
34-933-160-237
Center for Genomic Regulation

Public Release: 26-Jul-2017
University of Rochester awarded $19 million to coordinate national science program
The University of Rochester has been awarded $19 million from the National Center for Advancing Translational Sciences (NCATS) at the National Institutes of Health to coordinate a network of more than 50 institutions across the country. The network aims to help researchers turn scientific discoveries into health benefits faster.
National Institutes of Health, National Centers for Advancing Translational Sciences

Contact: Susanne Pallo
susanne_pallo@urmc.rochester.edu
University of Rochester Medical Center

Public Release: 26-Jul-2017
Inventions by young KTU researchers can identify early stages of flatfeet condition
Of all human organs, the most pressure is endured by the feet, which are carrying all the weight of a person while walking. The change of feet pressure can serve as a perfect indicator for diagnosing occurrence and development of certain heath conditions, such as feet pathologies from diabetes, toe deformation and flatfeet condition.

Contact: Aldona Steponaviciute
aldona.steponaviciute@ktu.lt
370-612-55857
Kaunas University of Technology

Showing releases 176-200 out of 966.

<< < 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 > >>