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Key: Meeting M      Journal J      Funder F

Showing releases 251-275 out of 948.

<< < 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 > >>

Public Release: 30-Mar-2017
Biomedical Optics Express
Researchers watch blood vessels develop in whole Zebrafish embryos
For the first time, researchers have followed the development of blood vessels in zebrafish embryos without using any labels or contrast agents, which may disturb the biological processes under study.

Contact: Joshua Miller
The Optical Society

Public Release: 30-Mar-2017
Aging: Cell coordination breakdown
Scientists have resolved a key question in aging research by showing how mouse immune cells of different ages respond to stimulation. Study demonstrates weaker response of older cells is due to their coordination breaking down, making their response to immune stimulation more variable. Single-cell sequencing technology allows scientists to profile individual cells independently to view cellular activity in high resolution.
EMBL, European Research Council, EMBO Young Investigators Programme, Cancer Research UK, MRC Biostatistics Unit, Wellcome Trust, BBSRC CASE Studentship with Abcam plc

Contact: Mary Todd Bergman
European Molecular Biology Laboratory - European Bioinformatics Institute

Public Release: 30-Mar-2017
npj Regenerative Medicine
Blind tadpoles learn visually with eyes grafted onto tail, neurotransmitter drug treatment
Blind tadpoles were able to process visual information from eyes grafted onto their tails after being treated with a small molecule neurotransmitter drug that augmented innervation, integration, and function of the transplanted organs. The work, which used a pharmacological reagent already approved for use in humans, provides a potential road map for promoting innervation -- the supply of nerves to a body part -- in regenerative medicine.
The Allen Discovery Center, The Paul G. Allen Frontiers Group, The G. Harold and Leila Y. Mathers Charitable Foundation

Contact: Patrick Collins
Tufts University

Public Release: 30-Mar-2017
PLOS Computational Biology
Brain's role in Tourette tics simulated in new computational model
A new computer-based brain simulation shows that motor tics in Tourette syndrome may arise from interactions between multiple areas of the brain, rather than a single malfunctioning area, according to a study published in PLOS Computational Biology.

Contact: Daniele Caligiore

Public Release: 29-Mar-2017
Future Medicinal Chemistry
Choosing a simpler path to drug discovery
Researchers from Kyoto University, MIT, and ETH Zurich have developed a compact drug discovery method using simple models and small data sets. Their findings appeared March 6 in the journal Future Medicinal Chemistry.
Japan Society for the Promotion of Science

Contact: David Kornhauser
Kyoto University

Public Release: 29-Mar-2017
2017 American Medical Informatics Association Joint Summits on Translational Science
'KinderMining:' Tackling big data sets by keeping things simple
With about 100 lines of code, a Morgridge Institute for Research team has unleashed a fast, simple and predictive text-mining tool that may turbo-charge big biomedical pursuits such as drug repurposing and stem cell treatments.
National Institutes of Health

Contact: Courtni Kopietz
Morgridge Institute for Research

Public Release: 28-Mar-2017
Proceedings of the National Academy of Sciences
It is easier for a DNA knot...
How can long DNA filaments, which have convoluted and highly knotted structure, manage to pass through the tiny pores of biological systems? This is the fascinating question addressed by Antonio Suma and Cristian Micheletti, researchers at the International School for Advanced Studies (SISSA) in Trieste who used computer simulations to investigate the options available to the genetic material in such situations. The study has just been published in PNAS.

Contact: Donato Ramani
Scuola Internazionale Superiore di Studi Avanzati

Public Release: 28-Mar-2017
ACS Synthetic Biology
Sharing expert experimental knowledge to expedite design
A new repository of metabolic information provides a quick tool for designing useful synthetic biological systems.

Contact: Michelle D'Antoni
King Abdullah University of Science & Technology (KAUST)

Public Release: 27-Mar-2017
For the birds: New prediction method sheds brighter light on flight
Sponsored by the Office of Naval Research, researchers at Stanford University found a new way to precisely measure the vortices -- circular patterns of rotating air -- created by birds' wings during flight. The results shed greater light on how these creatures produce enough lift to fly.

Contact: Bob Freeman
Office of Naval Research

Public Release: 27-Mar-2017
Recent Patents on Biotechnology
Patent analysis highlights importance of bioactives of saffron
Increased stress levels, sleep disorders and obesity have become hallmarks of present lifestyle. These conditions are often correlated with serious health problems such as cancer, diabetes, cerebral ischemia, stroke, etc.

Contact: Faizan ul Haq
Bentham Science Publishers

Public Release: 27-Mar-2017
Nature Biotechnology
New tool allows analysis of single-cell RNA data in pre-malignant tumours
Wellcome Trust Sanger Institute scientists and their collaborators have developed a new analysis tool that showed, for the first time, which genes were expressed by individual cells in different genetic versions of a benign blood cancer. Reported in Nature Methods today, the new computer tool -- Single Cell Consensus Clustering -- was shown to be more accurate and robust than existing methods of analyzing single-cell RNA sequence data, and is freely available for researchers to use.
Bloodwise, Wellcome Trust, Medical Research Council, Kay Kendall Leukaemia Fund, Cambridge NIHR Biomedical Research Center, Cambridge Experimental Cancer Medicine Centre, Leukemia and Lymphoma Society of America

Contact: Samantha Wynne
Wellcome Trust Sanger Institute

Public Release: 24-Mar-2017
'Bench to bedside to bench'
It's time to update the old 'bench-to-bedside' shorthand, researchers at The Jackson Laboratory, NHGRI and institutions across the US declare.

Contact: Sarah Laskowski
Jackson Laboratory

Public Release: 23-Mar-2017
Nature Communications
Scientists reveal hidden structures in bacterial DNA
Researchers at the Centre for Genomic Regulation (CRG) in Barcelona, Spain, have described the 3D structure of the genome in the extremely small bacteria Mycoplasma pneumoniae. They discovered previously unknown arrangements of DNA within this tiny bacteria, which are also found in larger cells. Their findings suggest that this type of organisation is a universal feature of living cells.
European Union Seventh Framework Programme, European Research Council, EU Horizon 2020 research and innovation program, Fundación Botín, Spanish Ministry of Economy and Competitiveness, ISCIII-Sub- dirección General

Contact: Laia Cendros
Center for Genomic Regulation

Public Release: 23-Mar-2017
New CDISC data standard aids development of therapies for Ebola virus
The Clinical Data Interchange Standards Consortium (CDISC) and the Infectious Diseases Data Observatory (IDDO) announce the availability of a new standard to assist in the collection, aggregation and analysis of Ebola virus disease (EVD) research data. This standard is for use in EVD trials, leading to potential treatments and public health surveillance for this disease.

Contact: Anne Whitehouse
Infectious Diseases Data Observatory

Public Release: 22-Mar-2017
Scientific Reports
Machine learning lets scientists reverse-engineer cellular control networks
Researchers from Tufts University and the University of Maryland, Baltimore County used machine learning on the Stampede supercomputer to model the cellular control network that determines how tadpoles develop. Using that model, they reverse-engineered a drug intervention that created tadpoles with a form of mixed pigmentation never before seen in nature. They plan to use the method for cancer therapies and regenerative medicine.
National Science Foundation, Paul G. Allen Frontiers Group, The G. Harold and Leila Y. Mathers Charitable Foundation

Contact: Aaron Dubrow
University of Texas at Austin, Texas Advanced Computing Center

Public Release: 21-Mar-2017
Molecular Metabolism
SIB accelerates the fight against diabetes with several pan-European projects
Recent advances in the fight against type 2 diabetes (T2D) result from a pan-European collaborative project, called IMIDIA, in which the SIB Swiss Institute of Bioinformatics is closely involved since 2010. SIB was in charge of both coordinating the large amount of patients' data (acting as Data Coordination Centre, DCC) as well as analysing the data to find biomarkers for early detection of the disease.

Contact: Maia Berman
Swiss Institute of Bioinformatics

Public Release: 20-Mar-2017
Nature Methods
Gene editing technique helps find cancer's weak spots
Genetic mutations that cause cancer also weaken cancer cells, allowing researchers to develop drugs that will selectively kill them. This is called 'synthetic lethality' because the drug is only lethal to mutated (synthetic) cells. Researchers at UC San Diego School of Medicine and Jacobs School of Engineering developed a method to search for synthetic-lethal gene combinations. The technique, published March 20 in Nature Methods, uncovered 120 new opportunities for cancer drug development.
National Institutes of Health, Burroughs Wellcome Fund, March of Dimes Foundation, Sidney Kimmel Foundation, California Institute for Regenerative Medicine, UC San Diego Clinical and Translational Research Institute Grant

Contact: Heather Buschman
University of California - San Diego

Public Release: 20-Mar-2017
Nature Methods
Data published in Nature Methods demonstrate breakthrough ability to accurately detect somatic single nucleotide variations in single cells
Before scientists can analyze the genome of a single cell, they must first obtain sufficient amounts of its DNA by whole genome amplification (WGA). But WGA typically produce errors that falsely indicate the presence of mutations and obscure the detection of any real somatic mutations. SingulOmics Corporation announced a Nature Methods publication demonstrating the game changing technology that enables accurate detection of somatic single nucleotide variations in single cells not possible in any prior methods.

Contact: Scott Rieger
SingulOmics Corporation

Public Release: 20-Mar-2017
Proceedings of the National Academy of Sciences
Vaccine, improved treatment are keys to control of a surging HIV pandemic
Development and widespread use of a vaccine that's even partially effective against HIV, along with more progress toward diagnosis and treatment, offer the best hopes for turning the corner on a global pandemic that's still spiraling out of control, researchers reported today.
National Institutes of Health

Contact: Jan Medlock
Oregon State University

Public Release: 17-Mar-2017
Scientific Reports
TGen study of ASU football team produces largest known dataset for concussion diagnostics
Following a three-year study of the Arizona State University football program, researchers at the Translational Genomics Research Institute have created the largest dataset to date of extracellular small RNAs, which are potential biomarkers for diagnosing medical conditions, including concussions. Details of the dataset were published today in Scientific Reports, an online open-access journal of the Nature Publishing Group.
Riddell Inc., Flinn Foundation, TGen Foundation

Contact: Steve Yozwiak
The Translational Genomics Research Institute

Public Release: 16-Mar-2017
PLOS Computational Biology
A blood test for autism
An algorithm based on levels of metabolites found in a blood sample can accurately predict whether a child is on the autism spectrum of disorder (ASD), based upon a recent study.
National Institutes of Health

Contact: Mary Martialay
Rensselaer Polytechnic Institute

Public Release: 16-Mar-2017
Proceedings of the National Academy of Sciences
Computer simulation of protein synthesis reveals awesome complexity of cell machinery
A Japanese research team led by Osaka University and Riken ran computer simulations of protein production. The model system, based on E. coli, contained the bare minimum for assembling proteins: 241 chemicals undergoing 968 reactions for 1,000 seconds. Many of these chemicals twice reached steady concentrations, only to be suddenly depleted at a later stage. The researchers believe the build-up and collapse of steady concentrations is characteristic of large-scale reactions, and vital for controlling the body's chemistry.
Japan Society for the Promotion of Science, Japan Science and Technology

Contact: Saori Obayashi
Osaka University

Public Release: 15-Mar-2017
Applications in Plant Sciences
Better barcoding: New library of DNA sequences improves plant identification
Researchers from the Department of Environmental Science at Emory University have used publicly available data to develop a sequence library of the rbcL gene, a popular barcode in plants, for use in DNA metabarcoding studies. Using both the rbcL and an already developed ITS2 library improved the accuracy of species identification and will allow advances including improved assessments of nutritional supplements and monitoring of bee populations.
US Army Research Office

Contact: Beth Parada
Botanical Society of America

Public Release: 15-Mar-2017
Detecting blood clot risk using biomarkers
Researchers at Boston Medical Center (BMC) and Boston University School of Medicine (BUSM) aim to increase survival rates among these patients by identifying new and validating existing biomarkers.
NIH/National Cancer Institute

Contact: Tim Viall
Boston University School of Medicine

Public Release: 15-Mar-2017
PLOS Biology
Luxembourg researchers decipher how the body controls stem cells
Stem cells are unspecialised cells that can develop into any type of cell in the human body. So far, however, scientists only partially understand how the body controls the fate of these all-rounders, and what factors decide whether a stem cell will differentiate, for example, into a blood, liver or nerve cell. Researchers from the University of Luxembourg and an international team have now identified an ingenious mechanism by which the body orchestrates the regeneration of red and white blood cells from progenitor cells.

Contact: Thomas Klein
University of Luxembourg

Showing releases 251-275 out of 948.

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