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Key: Meeting M      Journal J      Funder F

Showing releases 301-325 out of 946.

<< < 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 > >>

Public Release: 27-Mar-2017
Recent Patents on Biotechnology
Patent analysis highlights importance of bioactives of saffron
Increased stress levels, sleep disorders and obesity have become hallmarks of present lifestyle. These conditions are often correlated with serious health problems such as cancer, diabetes, cerebral ischemia, stroke, etc.

Contact: Faizan ul Haq
Bentham Science Publishers

Public Release: 27-Mar-2017
Nature Biotechnology
New tool allows analysis of single-cell RNA data in pre-malignant tumours
Wellcome Trust Sanger Institute scientists and their collaborators have developed a new analysis tool that showed, for the first time, which genes were expressed by individual cells in different genetic versions of a benign blood cancer. Reported in Nature Methods today, the new computer tool -- Single Cell Consensus Clustering -- was shown to be more accurate and robust than existing methods of analyzing single-cell RNA sequence data, and is freely available for researchers to use.
Bloodwise, Wellcome Trust, Medical Research Council, Kay Kendall Leukaemia Fund, Cambridge NIHR Biomedical Research Center, Cambridge Experimental Cancer Medicine Centre, Leukemia and Lymphoma Society of America

Contact: Samantha Wynne
Wellcome Trust Sanger Institute

Public Release: 24-Mar-2017
'Bench to bedside to bench'
It's time to update the old 'bench-to-bedside' shorthand, researchers at The Jackson Laboratory, NHGRI and institutions across the US declare.

Contact: Sarah Laskowski
Jackson Laboratory

Public Release: 23-Mar-2017
Nature Communications
Scientists reveal hidden structures in bacterial DNA
Researchers at the Centre for Genomic Regulation (CRG) in Barcelona, Spain, have described the 3D structure of the genome in the extremely small bacteria Mycoplasma pneumoniae. They discovered previously unknown arrangements of DNA within this tiny bacteria, which are also found in larger cells. Their findings suggest that this type of organisation is a universal feature of living cells.
European Union Seventh Framework Programme, European Research Council, EU Horizon 2020 research and innovation program, Fundación Botín, Spanish Ministry of Economy and Competitiveness, ISCIII-Sub- dirección General

Contact: Laia Cendros
Center for Genomic Regulation

Public Release: 23-Mar-2017
New CDISC data standard aids development of therapies for Ebola virus
The Clinical Data Interchange Standards Consortium (CDISC) and the Infectious Diseases Data Observatory (IDDO) announce the availability of a new standard to assist in the collection, aggregation and analysis of Ebola virus disease (EVD) research data. This standard is for use in EVD trials, leading to potential treatments and public health surveillance for this disease.

Contact: Anne Whitehouse
Infectious Diseases Data Observatory

Public Release: 22-Mar-2017
Scientific Reports
Machine learning lets scientists reverse-engineer cellular control networks
Researchers from Tufts University and the University of Maryland, Baltimore County used machine learning on the Stampede supercomputer to model the cellular control network that determines how tadpoles develop. Using that model, they reverse-engineered a drug intervention that created tadpoles with a form of mixed pigmentation never before seen in nature. They plan to use the method for cancer therapies and regenerative medicine.
National Science Foundation, Paul G. Allen Frontiers Group, The G. Harold and Leila Y. Mathers Charitable Foundation

Contact: Aaron Dubrow
University of Texas at Austin, Texas Advanced Computing Center

Public Release: 21-Mar-2017
Molecular Metabolism
SIB accelerates the fight against diabetes with several pan-European projects
Recent advances in the fight against type 2 diabetes (T2D) result from a pan-European collaborative project, called IMIDIA, in which the SIB Swiss Institute of Bioinformatics is closely involved since 2010. SIB was in charge of both coordinating the large amount of patients' data (acting as Data Coordination Centre, DCC) as well as analysing the data to find biomarkers for early detection of the disease.

Contact: Maia Berman
Swiss Institute of Bioinformatics

Public Release: 20-Mar-2017
Nature Methods
Gene editing technique helps find cancer's weak spots
Genetic mutations that cause cancer also weaken cancer cells, allowing researchers to develop drugs that will selectively kill them. This is called 'synthetic lethality' because the drug is only lethal to mutated (synthetic) cells. Researchers at UC San Diego School of Medicine and Jacobs School of Engineering developed a method to search for synthetic-lethal gene combinations. The technique, published March 20 in Nature Methods, uncovered 120 new opportunities for cancer drug development.
National Institutes of Health, Burroughs Wellcome Fund, March of Dimes Foundation, Sidney Kimmel Foundation, California Institute for Regenerative Medicine, UC San Diego Clinical and Translational Research Institute Grant

Contact: Heather Buschman
University of California - San Diego

Public Release: 20-Mar-2017
Nature Methods
Data published in Nature Methods demonstrate breakthrough ability to accurately detect somatic single nucleotide variations in single cells
Before scientists can analyze the genome of a single cell, they must first obtain sufficient amounts of its DNA by whole genome amplification (WGA). But WGA typically produce errors that falsely indicate the presence of mutations and obscure the detection of any real somatic mutations. SingulOmics Corporation announced a Nature Methods publication demonstrating the game changing technology that enables accurate detection of somatic single nucleotide variations in single cells not possible in any prior methods.

Contact: Scott Rieger
SingulOmics Corporation

Public Release: 20-Mar-2017
Proceedings of the National Academy of Sciences
Vaccine, improved treatment are keys to control of a surging HIV pandemic
Development and widespread use of a vaccine that's even partially effective against HIV, along with more progress toward diagnosis and treatment, offer the best hopes for turning the corner on a global pandemic that's still spiraling out of control, researchers reported today.
National Institutes of Health

Contact: Jan Medlock
Oregon State University

Public Release: 17-Mar-2017
Scientific Reports
TGen study of ASU football team produces largest known dataset for concussion diagnostics
Following a three-year study of the Arizona State University football program, researchers at the Translational Genomics Research Institute have created the largest dataset to date of extracellular small RNAs, which are potential biomarkers for diagnosing medical conditions, including concussions. Details of the dataset were published today in Scientific Reports, an online open-access journal of the Nature Publishing Group.
Riddell Inc., Flinn Foundation, TGen Foundation

Contact: Steve Yozwiak
The Translational Genomics Research Institute

Public Release: 16-Mar-2017
PLOS Computational Biology
A blood test for autism
An algorithm based on levels of metabolites found in a blood sample can accurately predict whether a child is on the autism spectrum of disorder (ASD), based upon a recent study.
National Institutes of Health

Contact: Mary Martialay
Rensselaer Polytechnic Institute

Public Release: 16-Mar-2017
Proceedings of the National Academy of Sciences
Computer simulation of protein synthesis reveals awesome complexity of cell machinery
A Japanese research team led by Osaka University and Riken ran computer simulations of protein production. The model system, based on E. coli, contained the bare minimum for assembling proteins: 241 chemicals undergoing 968 reactions for 1,000 seconds. Many of these chemicals twice reached steady concentrations, only to be suddenly depleted at a later stage. The researchers believe the build-up and collapse of steady concentrations is characteristic of large-scale reactions, and vital for controlling the body's chemistry.
Japan Society for the Promotion of Science, Japan Science and Technology

Contact: Saori Obayashi
Osaka University

Public Release: 15-Mar-2017
Applications in Plant Sciences
Better barcoding: New library of DNA sequences improves plant identification
Researchers from the Department of Environmental Science at Emory University have used publicly available data to develop a sequence library of the rbcL gene, a popular barcode in plants, for use in DNA metabarcoding studies. Using both the rbcL and an already developed ITS2 library improved the accuracy of species identification and will allow advances including improved assessments of nutritional supplements and monitoring of bee populations.
US Army Research Office

Contact: Beth Parada
Botanical Society of America

Public Release: 15-Mar-2017
Detecting blood clot risk using biomarkers
Researchers at Boston Medical Center (BMC) and Boston University School of Medicine (BUSM) aim to increase survival rates among these patients by identifying new and validating existing biomarkers.
NIH/National Cancer Institute

Contact: Tim Viall
Boston University School of Medicine

Public Release: 15-Mar-2017
PLOS Biology
Luxembourg researchers decipher how the body controls stem cells
Stem cells are unspecialised cells that can develop into any type of cell in the human body. So far, however, scientists only partially understand how the body controls the fate of these all-rounders, and what factors decide whether a stem cell will differentiate, for example, into a blood, liver or nerve cell. Researchers from the University of Luxembourg and an international team have now identified an ingenious mechanism by which the body orchestrates the regeneration of red and white blood cells from progenitor cells.

Contact: Thomas Klein
University of Luxembourg

Public Release: 14-Mar-2017
Aging Cell
Benchmark database of lifespan-extending drugs announced
Scientists announced the benchmark database of lifespan-extending drugs encompassing 418 compounds with lifespan-extension data across 27 different model organisms, revealing that the majority of age-related pathways have yet to be targeted pharmacologically.
Wellcome Trust, Israel Ministry of Science and Technology

Contact: Charlotte Casebourne
Biogerontology Research Foundation

Public Release: 13-Mar-2017
Proceedings of the National Academy of Sciences
The controversial origin of a symbol of the American west
New research by Professor Beth Shapiro of the UC Santa Cruz Genomics Institute and University of Alberta Professor Duane Froese has identified North America's oldest bison fossils and helped construct a bison genealogy establishing that a common maternal ancestor arrived between 130,000 and 195,000 years ago, during a previous ice age.
Gordon and Betty Moore Foundation, National Science Foundation

Contact: Alexis Morgan
University of California - Santa Cruz

Public Release: 13-Mar-2017
Research Ideas & Outcomes
Legitimacy of reusing images from scientific papers addressed
Scientific research builds on previous breakthroughs and publications, and yet access to data is often legally restricted. A recent paper by taxonomists and copyright experts published in the open science journal Research Ideas and Outcomes as part of the EU BON Collection, explores the application of copyright law and the reuse of published images as biodiversity data.

Contact: Donat Agosti
Pensoft Publishers

Public Release: 10-Mar-2017
CNIC coordinates an EU project to foster partnership between researchers in academia and industry
The Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC) coordinates an EU project to foster partnership between researchers in academia and industry. The 4DHeart project is underpinned by a €1.5 million budget spread over 4 years.
European Union

Contact: Fatima Lois
Centro Nacional de Investigaciones Cardiovasculares

Public Release: 10-Mar-2017
Scientific Reports
Researchers find a gene that causes Opitz C syndrome
The study, published in the journal Scientific Reports, identifies the gene that causes Opitz C syndrome in the only patient diagnosed with this ultra-rare disorder in Catalonia, which affects only sixty people in the world. The identified mutation in the gene MAGEL2 coincides with the one seen in some patients with another minority disease, the Schaaf-Yang syndrome.
FECYT, Precipita

Contact: Laia Cendrós
Center for Genomic Regulation

Public Release: 9-Mar-2017
New Phytologist
FRED database gathers root traits to advance understanding of below-ground plant ecology
Oak Ridge National Laboratory scientists have released a new global, centralized database of plant root traits, or identifying characteristics, that can advance our understanding of how the hidden structure of plants below ground may interact with and relate to life above ground.
US Department of Energy Office of Science

Contact: Stephanie G. Seay
DOE/Oak Ridge National Laboratory

Public Release: 9-Mar-2017
Cell Stem Cell
The intestine has a reservoir of stem cells that are resistant to chemotherapy
Researchers at the IRB Barcelona headed by ICREA investigator Eduard Batlle, head of the Colorectal Cancer Laboratory, have discovered a new group of intestinal stem cells with very different characteristics to those of the abundant and active stem cells already known in this organ. The study has been published in Cell Stem Cell. These new group of stem cells are quiescent, that is to say, they do not proliferate and are apparently dormant.
European Research Council (ERC), Botín Foundation, Spanish Ministry of Science and Competitiveness

Contact: Sònia Armengou
Institute for Research in Biomedicine (IRB Barcelona)

Public Release: 9-Mar-2017
Nature Protocols
Innovative technique greatly increases sensitivity of DNA sequencing
OICR researchers, together with international collaborators, have invented a technique to avoid a major problem with common laboratory techniques and improve the sensitivity of important cancer tests. The findings, recently published in the journal Nature Protocols, describe a process by which the sensitivity of DNA sequencing can be improved. The technology, called SiMSen-Seq, could aid in detecting the recurrence of cancers, catching possible disease relapses faster than current methods and improving patient outcomes.

Contact: Hal Costie
Ontario Institute for Cancer Research

Public Release: 8-Mar-2017
Proceedings of the National Academy of Sciences
New technology platform propels the use of 'organs-on-chips'
BWH has developed a novel technology platform that enables the continuous and automated monitoring of so-called 'organs-on-chips' -- tiny devices that incorporate living cells to mimic the biology of bona fide human organs.

Contact: Johanna Younghans
Brigham and Women's Hospital

Showing releases 301-325 out of 946.

<< < 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 > >>