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Key: Meeting M      Journal J      Funder F

Showing releases 326-350 out of 968.

<< < 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 > >>

Public Release: 3-Nov-2017
Scientific Data
RefEx, a web tool for a comfortable search of reference data for gene expression analysis
A large variety of data of life science (such as gene expression) is accumulated in the public database, but it is difficult to use. A web tool RefEx can easily search gene expression data available in public databases to obtain reference data for genetic analysis without bench-top experiments. RefEx is expected to contribute widely and greatly to life science and medical research as a powerful tool for gene expression research.
Integrated Database Project of the Ministry of Education, Culture, Sports, Science and Technology (MEXT) of Japan, National Bioscience Database Center (NBDC) of the Japan Science and Technology Agency (JST)

Contact: Mari T, Minowa
Research Organization of Information and Systems

Public Release: 2-Nov-2017
Biodiversity Data Journal
Artificial neural networks could power up curation of natural history collections
Fed with new knowledge for centuries, natural history collections contain critical data for many scientific endeavors. While recent efforts in mass digitization have already provided unprecedented insight by generating large datasets from these collections, a new pilot project -- one of the first of its kind -- suggests that the key to efficiently studying these data might lie in the new-age deep learning techniques. The research article is published in the open-access Biodiversity Data Journal.

Contact: Larry Dorr
Pensoft Publishers

Public Release: 1-Nov-2017
Two classes of GGAA-microsatellites in a Ewing sarcoma context
In a study published in PLOS ONE, researchers describe two types of GGAA-microsatellites and their roles in EWS/FLI binding and gene regulation in Ewing sarcoma. Ewing sarcoma is the second most common pediatric bone malignancy. It is initiated by chromosomal translocation t(11;22)(q24;q12), which creates the fusion protein and oncogenic driver EWS/FLI.
NIH/National Cancer Institute, The High Performance Computing Facility at the Research Institute, Nationwide Children's Hospital

Contact: Danielle Warner
Nationwide Children's Hospital

Public Release: 1-Nov-2017
Mapping the microbiome of...everything
In the Earth Microbiome Project, an extensive global team co-led by researchers at University of California San Diego, Pacific Northwest National Laboratory, University of Chicago and Argonne National Laboratory collected more than 27,000 samples from numerous, diverse environments around the globe. They analyzed the unique collections of microbes -- the microbiomes -- living in each sample to generate the first reference database of bacteria colonizing the planet.
John Templeton Foundation, W. M. Keck Foundation, DOE/Argonne National Laboratory, Australian Research Council, Extreme Science and Engineering Discovery Environment, National Science Foundation

Contact: Heather Buschman
University of California - San Diego

Public Release: 31-Oct-2017
Journal of Experimental Medicine
Elderly chromosomes activate genes differently than in the young
Grey hair, wisdom, and wrinkles on our skin mark us as we age, but it's the more subtle changes beneath the surface that make us old. Now, researchers have discovered that our chromosomes also wrinkle with age, changing how our immune system renews itself.
Jackson Laboratory Director's Innovation Fund, UConn Health Travelers Chair, National Institutes of Health

Contact: Kim Krieger
University of Connecticut

Public Release: 31-Oct-2017
Journal of Biological Chemistry
How an interest in bipolar disorder drugs led to a better understanding of leukemia
A research project that began 20 years ago with an interest in how lithium treats mood disorders has yielded insights into the progression of blood cancers such as leukemia. The research, which centers on a protein called GSK-3, will be published in the Nov. 3 issue of the Journal of Biological Chemistry.
National Institutes of Health, Hematological Malignancies Translational Center of Excellence, Abramson Cancer Center, Institute for Translational Medicine and Applied Therapeutics, University of Pennsylvania

Contact: Sasha Mushegian
American Society for Biochemistry and Molecular Biology

Public Release: 31-Oct-2017
Genome Biology
Genome scientists use UK Salmonella cases to shed light on African epidemic
Scientists at the University of Liverpool and Public Health England have used Salmonella genome data from a UK public health surveillance study to gain new insights into the Salmonella epidemic in sub-Saharan Africa.

Contact: Nicola Frost
University of Liverpool

Public Release: 30-Oct-2017
Nature Ecology & Evolution
White rot fungi's size explained by breadth of gene families involved
Armillaria fungi are among the most devastating fungal pathogens, causing root rot disease in more than 500 plant species found in forests, parks and vineyards. As white rot fungi, they are capable of breaking down all components of plant cell walls, a capability that interests bioenergy researchers. In Nature Ecology & Evolution, an international team analyzed and compared four Armillaria fungal genomes with those of related fungi to better understand the evolution of Armillaria's abilities.
DOE/Office of Science

Contact: David Gilbert
DOE/Joint Genome Institute

Public Release: 30-Oct-2017
NIH awards UTHealth's Vasanthi Jayaraman $2.6 million for brain research
The National Institutes of Health has presented its Maximizing Investigators' Research Award to Vasanthi Jayaraman, Ph.D., a professor of biochemistry and molecular biology with McGovern Medical School at The University of Texas Health Science Center at Houston (UTHealth). It is a $2.6 million, five-year award.

Contact: Rob Cahill
University of Texas Health Science Center at Houston

Public Release: 29-Oct-2017
Molecular Plant
Pumpkin genomes sequenced, revealing uncommon evolutionary history
For some, pumpkins conjure carved Halloween decorations, but for many people around the world, these gourds provide nutrition. Scientists at Boyce Thompson Institute (BTI) and the National Engineering Research Center for Vegetables in Beijing have sequenced the genomes of two important pumpkin species, Cucurbita maxima and Cucurbita moschata.
Beijing Scholar Program, Beijing Excellent Talents Program, Ministry of Agriculture of China, Beijing Natural Science Foundation, National Science Foundation

Contact: Keith Hannon
Boyce Thompson Institute

Public Release: 27-Oct-2017
Clinical Cancer Research
TGen-UCSF study uses genomics to make treatment calls for recurrent glioblastoma patients
Several patients with recurring glioblastoma, a deadly brain cancer, survived for more than a year in a clinical trial believed to be the first to use comprehensive DNA and RNA sequencing of a patient's tumor to inform treatment for these patients in real-time. The study was led by the Translational Genomics Research Institute (TGen), UC San Francisco (UCSF) and the Ivy Foundation Early Phase Clinical Trials Consortium.
The Ben & Catherine Ivy Foundation

Contact: Steve Yozwiak
The Translational Genomics Research Institute

Public Release: 26-Oct-2017
BMC Medical Genomics
TGen-USC study finds 'Precision Medicine' may not always be so precise
Precision Medicine in oncology, where genetic testing is used to determine the best drugs to treat cancer patients, is not always so precise when applied to some of the world's more diverse populations, according to a study led by the Translational Genomics Research Institute (TGen), an affiliate of City of Hope, and the Keck School of Medicine of the University of Southern California (USC).
The Ben & Catherine Ivy Foundation, Multiple Myeloma Research Foundation

Contact: Steve Yozwiak
The Translational Genomics Research Institute

Public Release: 26-Oct-2017
Insect Systematics and Evolution
Fly hunter has described 30 new species
Xiaolong Lin jokes that he likes non-biting midges because they don't bite. But he has also dedicated his academic career to describing new species, and has already discovered 30 species previously unknown to science.

Contact: Xiaolong Lin
Norwegian University of Science and Technology

Public Release: 26-Oct-2017
PLOS Computational Biology
Computational simulations suggest multiple sclerosis is a single disease
New research supports the idea that multiple sclerosis (MS), which has widely varying symptoms and progression in different patients, is nonetheless a single disease with common underlying mechanisms. The findings are published in PLOS Computational Biology.

Contact: Pablo Villoslada

Public Release: 25-Oct-2017
Proceedings of the National Academy of Sciences
Development of a highly-accurate computational model of human metabolism
KAIST team developed a computational framework that enables the reconstruction of a comprehensive computational model of human metabolism, which allows for an accurate prediction of personal metabolic features.
Technology Development Program to Solve Climate Changes on Systems Metabolic Engineering for Biorefineries

Contact: Younghye Cho
The Korea Advanced Institute of Science and Technology (KAIST)

Public Release: 23-Oct-2017
Nature Methods
Boost for lipid research: Austrian researchers facilitate lipid data analysis
Illnesses such as cancer and multiple sclerosis may also be associated with lipids. Disorders are difficult to assess due to the diversity of lipids. Austrian scientists from Graz present a new tool for the analysis of lipids in Nature Methods.
Austrian Science Fund

Contact: Gerhard Thallinger
Graz University of Technology

Public Release: 23-Oct-2017
Novel transdisciplinary study uncovers microbes that may one day deter major grape disease
Researchers at the University of California-Riverside (UCR) conducted a novel transdisciplinary study to characterize the microbial communities within the vascular system of grapevines and their connections with Pierce's disease, an economically significant disease of the California grape industry. Through the study, the researchers found potentially beneficial microbes that could one day be used as a deterrent to Xylella fastidiosa, the pathogen that causes Pierce's disease.

Contact: Phil Bogdan
American Phytopathological Society

Public Release: 20-Oct-2017
BU researchers create tool to measure, control protein aggregation
In the cover article in the current issue of Cell, BU Biomedical Engineer Ahmad S. Khalil along with colleagues from MIT and the Whitehead Institute for Biomedical Research, among others, describe the synthetic genetic tool they built to quantitatively sense, measure and manipulate protein aggregation in live cells. This may open the door to greater understanding and treatment of a range of maladies from Alzheimer's to type II diabetes.

Contact: Mike Seele
Boston University College of Engineering

Public Release: 19-Oct-2017
PLOS Biology
Studying insect behavior? Make yourself an ethoscope!
Fruit flies have surprising similarities to humans. The mysteries of a broad range of human conditions can be studied in detail in these organisms, however this often requires the use of expensive custom equipment. In a Community Page in the open-access journal PLOS Biology, Dr. Giorgio Gilestro from Imperial College London and colleagues present the ethoscope -- a cheap, easy-to-use and self-made customizable piece of equipment of their invention that can be used to study flies' behavior.

Contact: Giorgio Gilestro

Public Release: 18-Oct-2017
American Society of Human Genetics 2017 Annual Meeting
Online resource enables open data sharing for rare Mendelian diseases
MyGene2, a new open data resource, helps patients with rare genetic conditions, clinicians, and researchers share information, connect with one another, and enable faster gene discovery, according to results presented at the American Society of Human Genetics (ASHG) 2017 Annual Meeting in Orlando, Fla.

Contact: Nalini Padmanabhan
American Society of Human Genetics

Public Release: 17-Oct-2017
TGen develops processing procedures for 'single-cell' sequencing
The Translational Genomics Research Institute (TGen) today announced grant support from the Chan Zuckerberg Initiative (CZI) donor advised fund, an advised fund of the Silicon Valley Community Foundation, that will help revolutionize how researchers identify the genetic source of diseases and how best to treat each patient.
Chan Zuckerberg Initiative

Contact: Steve Yozwiak
The Translational Genomics Research Institute

Public Release: 17-Oct-2017
Molecular Cancer Research
Therapeutic form of arsenic is a potential treatment for deadly type of brain cancer
In a study led by Northwestern University Feinberg School of Medicine and the Translational Genomics Research Institute (TGen), this anti-cancer agent is being considered for use against glioblastoma multiforme (GBM), the most common and aggressive type of deadly brain tumors. The study was published today in Molecular Cancer Research, a journal of the American Association for Cancer Research (AACR).
National Institutes of Health, US Department of Veterans Affairs, Ben & Catherine Ivy Foundation

Contact: Steve Yozwiak
The Translational Genomics Research Institute

Public Release: 17-Oct-2017
2017 Borlaug Dialogue International Symposium
DuPont Pioneer and Donald Danforth Plant Science Center collaborate
The Danforth Center is applying CRISPR-Cas technology to staple food crops such as cassava and sorghum to produce planting materials with improved disease resistance, nutritional value and enhanced resilience to biotic stresses.

Contact: Melanie Bernds
Donald Danforth Plant Science Center

Public Release: 17-Oct-2017
JAX, Seven Bridges to build centralized data platform to advance cancer research
The Jackson Laboratory (JAX), a nonprofit biomedical research institution, and Seven Bridges, the leading biomedical data analysis company, today announced a new collaboration to build an NCI-funded data platform to accelerate translational research using patient-derived tumor xenograft (PDX) datasets.
NIH/National Cancer Institute

Contact: News
Jackson Laboratory

Public Release: 17-Oct-2017
GA4GH 5th Plenary Meeting
GA4GH strikes formal collaborations with 15 international genomic data initiatives
GA4GH has struck formal collaborations with 15 international genomic data initiatives as 2017 Driver Projects as part of GA4GH Connect, a new phase of the organization focused on driving uptake of standards and frameworks for genomic data sharing within the research and healthcare communities in order to enable responsible sharing of clinical-grade genomic data by 2022.

Contact: Angela Page
Global Alliance for Genomics and Health

Showing releases 326-350 out of 968.

<< < 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 > >>