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Key: Meeting M      Journal J      Funder F

Showing releases 451-475 out of 952.

<< < 14 | 15 | 16 | 17 | 18 | 19 | 20 | 21 | 22 | 23 > >>

Public Release: 21-Mar-2016
Nature Reviews Genetics
Beyond DNA: TGen points the way to enhanced precision medicine with RNA sequencing
Researchers at the Translational Genomics Research Institute (TGen) are showing how genetic analysis using RNA sequencing can vastly enhance that understanding, providing doctors and their patients with more precise tools to target the underlying causes of disease, and help recommend the best course of action. Published today in the journal Nature Reviews Genetics, TGen scientists highlight the many advantages of using RNA-sequencing in the detection and management of everything from cancer to infectious diseases
Ben & Catherine Ivy Foundation of Scottsdale, National Center for Advancing Translational Sciences, Stand Up To Cancer-Melanoma Research Alliance Melanoma Dream Team Translational Cancer Research Grant

Contact: Steve Yozwiak
The Translational Genomics Research Institute

Public Release: 21-Mar-2016
Nature Methods
Supporting the bioimaging revolution
The rapid rise of high-resolution 3-D cellular imaging techniques in biology demands data solutions -- and EMBL is there to provide them.
Medical Research Council, Biotechnology and Biomedical Science Research Council, Wellcome Trust, EMBL

Contact: Mary Todd Bergman
European Molecular Biology Laboratory - European Bioinformatics Institute

Public Release: 21-Mar-2016
Top 50 most wanted fungi: New search function zooms in on the dark fungal diversity
There are many millions of undescribed fungi. As a result, public DNA sequence databases abound with fungal sequences that are unidentified even at the phylum level. Frustrated at this situation, an international group of researchers presents a search function to highlight the fungi we know the least about. The effort hopes to encourage community participation and speed up scientific progress in the enigmatic fungal kingdom. Their research is published in the open-access journal MycoKeys.

Contact: Dr. Henrik Nilsson
Pensoft Publishers

Public Release: 17-Mar-2016
Wrangler Supercomputer speeds through big data
A new kind of supercomputer called Wrangler is helping researchers speed through the bumpy terrain of big data and reach new discoveries, according to a special report at the Texas Advanced Computing Center. NSF-funded Wrangler is designed to be more user-friendly with a web-driven approach to high performance computing, including data analytics. The biologists, anthropologists, energy-efficiency experts, and astronomers profiled represent just a slice of the diverse community Wrangler supports.
National Science Foundation, US Department of Energy

Contact: Faith Singer-Villalobos
University of Texas at Austin, Texas Advanced Computing Center

Public Release: 17-Mar-2016
Optical Materials Express
New technique for rapidly killing bacteria using tiny gold disks and light
Researchers have developed a new technique for killing bacteria in seconds using highly porous gold nanodisks and light, according to a study published today in Optical Materials Express, a journal published by The Optical Society. The method could one day help hospitals treat some common infections without using antibiotics, which could help reduce the risk of spreading antibiotics resistance.

Contact: Rebecca Andersen
The Optical Society

Public Release: 17-Mar-2016
Calcium controls sleep duration in mice
University of Tokyo and RIKEN researchers have identified seven genes responsible for causing mice to stay awake or fall asleep based on a theoretical model of sleep and on experiments using 21 different genetically modified mice, some of which showed different sleep durations. Researchers hope that their research will contribute to the understanding and treatment of sleep disorders and associated neurodegenerative diseases.

Contact: Hiroki Ueda
University of Tokyo

Public Release: 11-Mar-2016
Citizen science project draws up the first oral microbiome map for the youth
In the year following its launch, this project has brought bioinformatics closer to society, and highlighted the importance of the microbiome, with the participation of over 4,000 individuals. The results of the scientific study have revealed an initial oral microbiome map of young people, pointing to significant differences according to their geographic location, dietary or lifestyle factors, such as smoking or owning a pet.
la Caixa Bank Foundation, Severo Ochoa Programme of Excellence, Spanish Ministry of Economy and Competitiveness

Contact: Laia Cendros
Center for Genomic Regulation

Public Release: 11-Mar-2016
Science Advances
Quality control for genetic sequencing
Genetic sequencing is in widespread use today, but until now has not been accurate enough to identify an antibody immune response. Now, thanks to a new control system based on genetic barcodes, the technique is far more reliable -- and ready for use in the development of vaccines and antibody drugs.

Contact: Dr. Sai Reddy
ETH Zurich

Public Release: 10-Mar-2016
Genome Biology and Evolution
Dramatically dynamic genomic evolution of a mighty mite
Sequencing and comparative analysis of the genome of the Western Orchard predatory mite has revealed intriguingly-extreme genomic evolutionary dynamics through an international research effort co-led by scientists from the University of Geneva and the SIB Swiss Institute of Bioinformatics.

Contact: Robert M. Waterhouse
Swiss Institute of Bioinformatics

Public Release: 10-Mar-2016
BMC Bioinformatics
Scientists developed a robust method for analysis of intestinal bacteria
A research group from Russia have proposed a new method for the comparison of microbiota (bacteria living in and on human body; metagenome) DNA sequences. The method makes it possible to more effectively and quickly solve the task of comparing samples and can be easily embedded in the data-analysis process of any metagenome study. The developed technique allows to investigate differences between bacterial communities in our organisms more efficient and accurate.

Contact: Valerii Roizen
Moscow Institute of Physics and Technology

Public Release: 10-Mar-2016
Nature Methods
Tracking the social networks of genes disrupted in complex diseases
Your personal risk of developing complex diseases such as diabetes, depression or cancer is influenced in part by genetic variants, that is, letters in your DNA sequence that differ between people. These variants disrupt networks of interacting genes in different tissues of your body, two studies published in Nature Methods and PLOS Computational Biology found.

Contact: Daniel Marbach
Swiss Institute of Bioinformatics

Public Release: 9-Mar-2016
PLOS Computational Biology
'Big data' drills down into metabolic details
Rice University bioengineers have introduced a fast computational method to model tissue-specific metabolic pathways that may help find new therapeutic targets for cancer and other diseases.
National Science Foundation

Contact: David Ruth
Rice University

Public Release: 9-Mar-2016
Nature Genetics
Spotted Gar genome links humans to vertebrate ancestry
The Spotted Gar is an unusual fish whose genome sequence has been released in a recent study highlighted in Nature Genetics. This fish has surprising genetic similarities and ancestral qualities which are informative about the evolution of many vertebrate animals -- including humans.

Contact: Hayley London
Earlham Institute

Public Release: 8-Mar-2016
Brain activity of nematodes seeking food offers new view on sleep
If you have trouble sleeping, the neurons in your brain may be firing like those in roundworms randomly seeking food in the absence of clues, says University of Oregon biologist Shawn R. Lockery. That connection is proposed in a theoretical neuroscience paper co-authored by 12 researchers at 10 institutions.
National Institutes of Health

Contact: Jim Barlow
University of Oregon

Public Release: 7-Mar-2016
New England Journal of Medicine
Mutated gene safeguards against heart attacks
People with a specific gene mutation have a 50 percent lower risk of suffering a heart attack. This is what an international team of researchers headed by the cardiologist Professor Heribert Schunkert, medical director of the German Heart Center at the Technical University of Munich, discovered in a broad comparative study. If this gene were switched off with medications it could reduce the risk of coronary disease significantly.
National Institutes of Health, European Research Council, German Research Foundation, German Federal Ministry of Education and Research

Contact: Dr. Andreas Battenberg
Technical University of Munich (TUM)

Public Release: 7-Mar-2016
Nature Methods
Immunology meets single-cell sequencing
A new single-cell genomics method helps determine T-cell receptor sequences and extrapolate their response to disease. The technique will help research into immune response, autoimmune disease, cancer and vaccination. Uptake enables sequencing-based understanding of which T-cell receptors recognize specific invaders -- knowledge that could be used to speed up diagnosis.
European Research Council, Lister Institute for Preventative Medicine, EMBL, Wellcome Trust Sanger Institute

Contact: Mary Todd Bergman
European Molecular Biology Laboratory - European Bioinformatics Institute

Public Release: 7-Mar-2016
Nature Genetics
Zebrafish and humans have new biomedical friend in the spotted gar
The genome of a slowly evolving fish, the spotted gar, is so much like both zebrafish and humans that it can be used as a bridge species that could open a pathway to important advancements in biomedical research focused on human diseases.
National Institutes of Health

Contact: Jim Barlow
University of Oregon

Public Release: 3-Mar-2016
Highly realistic virtual neurons fruit of an Allen Institute and Blue Brain collaboration
The Allen Institute for Brain Science and the Blue Brain Project are deepening their collaboration. Today, the US-based Allen Institute is releasing a set of 40 computer models of neurons from the mouse visual cortex, created using tools developed by the Swiss-based Blue Brain Project at EPFL. Using Blue Brain technology, the researchers were able to reproduce the physiology and electrical activity of the neurons with an extremely high level of detail.

Contact: Lionel Pousaz
Ecole Polytechnique Fédérale de Lausanne

Public Release: 3-Mar-2016
DNA 'scrunching' occurs as RNA polymerase selects a position to begin synthesizing RNA
A research collaboration that combines novel 'big-data' informatics tools with expertise in basic biology has uncovered details of an essential process in life: how a crucial enzyme locates the site on DNA where it begins to direct the synthesis of RNA. This finding may aid in the discovery of new antimicrobial medicines, and the powerful technological approaches developed for this research may shed light on other essential cellular processes.
National Institutes of Health

Contact: John Ascenzi
Children's Hospital of Philadelphia

Public Release: 3-Mar-2016
Ancient viral invaders in our DNA help fight today's infections
Roughly eight percent of our DNA comes from viruses that infected our ancestors millions of years ago. New research by University of Utah geneticists shows that more than an oddity,the viral DNA switches on genes responsible for initiating an immune response. When removed, the innate immune system -- a first-responder to infection by pathogens including viruses -- does not function properly. The study shows that viral DNA functions in our body by helping us fight infections.
National Institutes of Health, Jane Coffin Childs Memorial Fund, Pew Charitable Trusts

Contact: Julie Kiefer
University of Utah Health Sciences

Public Release: 2-Mar-2016
Rare disease patients share info on MyGene2 web tool to assist with gene discovery
A new web tool, MyGene2, will enable patients and their families to join clinicians and scientists in the search for genes underlying rare disorders. The sharing of health information also will improve knowledge about how gene variants influence symptoms and other clinical features of Mendelian disorders.
NIH/National Human Genome Research Institute, NIH/National Heart, Lung and Blood Institute

Contact: Leila Gray
University of Washington Health Sciences/UW Medicine

Public Release: 2-Mar-2016
Scientific Reports
Overfishing increases fluctuations in aquatic ecosystems
Overfishing reduces fish populations and promotes smaller sizes in fish. The fish also reach sexual maturity earlier than normal. However, the impact of overfishing is not restricted to fish: as the predators at the top of the food web dwindle, the stability of the entire aquatic ecosystem is at risk.

Contact: Anna Kuparinen
University of Helsinki

Public Release: 2-Mar-2016
Genome Research
New method reveals high similarity between gorilla and human Y chromosome
A faster, less expensive method has been developed and used to learn the DNA sequence of the male-specific Y chromosome in the gorilla. The research reveals that a male gorilla's Y chromosome is more similar to a male human's Y chromosome than to a chimpanzee's. The technique works for any species, so it can be used to study male infertility disorders and male-specific mutations. It also can aid in conservation efforts.
National Science Foundation, Penn State University, Pennsylvania Department of Health, National Institutes of Health, John and Beverly Stauffer Foundation, Alice B. Tyler Charitable Trust, Leverhulme Trust

Contact: Barbara Kennedy
Penn State

Public Release: 1-Mar-2016
Scientific Reports
Regulating neuronal membrane lipids could be the key to Alzheimer's and Parkinson's
Using latest-generation molecular simulations researchers have demonstrated that a decrease in polyunsaturated lipids in neuronal membranes, as seen in Parkinson's and Alzheimer's sufferers, directly affects the binding rate of dopamine and adenosine receptors. The work was led by members IMIM (Hospital del Mar Medical Research Institute) and Pompeu Fabra University as well as researchers from the University of Tampere (Finland), and also involved scientists from the University of Barcelona.

Contact: Marta Calsina Freixas
IMIM (Hospital del Mar Medical Research Institute)

Public Release: 29-Feb-2016
Nature Structural & Molecular Biology
New software provides an overview of the big data of genome sequencing
Since researchers first succeeded in mapping the human genome back in 2003, the technological development has moved at warp speed, and the process which at that time took several years and billions of dollars can now be performed in a few days. In the Klaus Hansen research group at the Biotech Research & Innovation Centre, University of Copenhagen, researchers have developed a new type of software, which enables a much faster analysis and interpretation of the vast amounts of data provided by sequencing technology.
Danish National Research Foundation

Contact: Mads Lerdrup
University of Copenhagen, Biotech Research & Innovation Centre

Showing releases 451-475 out of 952.

<< < 14 | 15 | 16 | 17 | 18 | 19 | 20 | 21 | 22 | 23 > >>