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Key: Meeting M      Journal J      Funder F

Showing releases 626-650 out of 952.

<< < 21 | 22 | 23 | 24 | 25 | 26 | 27 | 28 | 29 | 30 > >>

Public Release: 1-Apr-2016
Engineered monomeric streptavidin
A novel streptavidin variant with improved biotin binding characteristics allows stable monovalent detection of biotinylated targets for imaging applications and can be recombinantly fused to introduce a biotin binding tag.

Contact: Philly Lim
World Scientific

Public Release: 31-Mar-2016
TGen and Mayo Clinic scientists issue report in Cell on advances in basal cell carcinoma
An article in the journal Cell by top scientists from the Translational Genomics Research Institute (TGen) and Mayo Clinic in Arizona details how two relatively new drugs are helping patients with basal cell carcinoma. Basal cell carcinoma is the most common type of skin cancer, producing nearly 2.8 million new cases annually in the US, and sunny Arizona has one of the world's highest incidences of skin cancer.

Contact: Steve Yozwiak
The Translational Genomics Research Institute

Public Release: 31-Mar-2016
Agewandte Chemie
Proving the genetic code's flexibility
Three-letter codons in a genome sequence can represent one of the 20 regularly used amino acids or stops. In the journal Angewandte Chemie International Ed., researchers from the US Department of Energy Joint Genome Institute and Yale University have discovered that microorganisms recognize more than one codon for selenocysteine. The finding adds credence to recent studies indicating that an organism's genetic vocabulary is not as constrained as had been long held.
DOE Office of Science, National Institute for General Medical Sciences

Contact: David Gilbert
DOE/Joint Genome Institute

Public Release: 31-Mar-2016
PacBio's SMRT sequencing provides scientists with a superior gorilla genome reference
Analysis of the gorilla genome will shed light on biological mechanisms behind speech, disease, neurological behavior, and other traits separating us from our closest primate relatives. The previous gorilla assembly, built with short-read and Sanger sequencing data, was highly fragmented, containing over 400,000 gaps and was constructed using the human genome as a guiding reference. The new assembly, started from scratch using the PacBio SMRT technology, dramatically improves the gorilla genome assembly for further research.

Contact: Nicole Litchfield

Public Release: 31-Mar-2016
A new approach to sequence and assemble primate genomes
An improved version of the gorilla genome assembly is offering new biological insights into its evolution, and to what makes humans different from this great ape primate. The new techniques used to sequence and assembly this gorilla genome hold promise for improving genetic research on human disease. The techniques create longer reads of DNA sequences to allow researchers to spot repeats and other variations more readily.

Contact: Leila Gray
University of Washington Health Sciences/UW Medicine

Public Release: 31-Mar-2016
American Journal of Human Genetics
Mom's smoking alters fetal DNA
A study of over 6,000 mothers and their newborn children -- one of the largest studies of its kind -- solidifies the evidence that smoking cigarettes while pregnant chemically modifies a fetus' DNA, mirroring patterns seen in adult smokers. The researchers also identify new development-related genes affected by smoking. The work, published March 31 in the American Journal of Human Genetics, suggests a potential explanation for the link between smoking during pregnancy and health complications in children.

Contact: Karen Zusi
Cell Press

Public Release: 30-Mar-2016
Human Brain Project's research platforms released
Public Release of Platforms Will Help Advance Collaborative Research in Neuroscience, Medicine, and Computing.

Contact: Lionel Pousaz
Ecole Polytechnique Fédérale de Lausanne

Public Release: 29-Mar-2016
Cell Reports
Infradian oscillation of circadian genes in a mouse model of bipolar disorder
Molecular basis of changes in mood and mood-associated behaviors are unknown. Researchers in Japan have succeeded in predicting states of mood-change-like behavior by studying the gene expression patterns in the brain in a bipolar disorder mouse model. They found that expressions of circadian rhythm-associated genes concomitantly change with mood-change-like behaviors in these mice. The current results also provide a novel insight into the molecular basis of bipolar disorder in the brain.

Contact: Tsuyoshi Miyakawa
Fujita Health University

Public Release: 28-Mar-2016
Research Ideas & Outcomes
Empowering stakeholders: FP7 project EU BON shares know-how on biodiversity data policies
Engagement with relevant political authorities and other stakeholders is of crucial importance for a research project, making sure its objectives are in tune with the real-world problems and its results provide adapted solutions. The EU-funded FP7 project EU BON shares the outcomes, lessons learned and conclusions from a series of three roundtable meetings designed to identify stakeholder needs and promote better collaboration between science and policy.

Contact: Dr. Katrin Vohland
Pensoft Publishers

Public Release: 28-Mar-2016
Current Biology
A world map of Neanderthal and Denisovan ancestry in modern humans
Most non-Africans possess at least a little bit Neanderthal DNA. But a new map of archaic ancestry -- published March 28 in Current Biology -- suggests that many bloodlines around the world, particularly of South Asian descent, may actually be a bit more Denisovan, a mysterious population of hominids that lived around the same time as the Neanderthals. The analysis also proposes that modern humans interbred with Denisovans about 100 generations after their trysts with Neanderthals.

Contact: Joseph Caputo
Cell Press

Public Release: 24-Mar-2016
Developing better drugs for asthma and high blood pressure
If a patient is ill and takes drugs for that illness, these drugs often lead to further illnesses and complications. An international research team from Bielefeld University, universities in Novosibirsk and Tomsk, Russia, and from the National Academy of Sciences of Ukraine in Kiev are studying how to prevent this problem. Starting in May, the Volkswagen Foundation will be funding this cooperation with about €235,000 for the next two years.
Volkswagen Stiftung

Contact: Dr. Ralf Hofestaedt
Bielefeld University

Public Release: 22-Mar-2016
Research Ideas & Outcomes
Making the most out of biological observations data
Creating and maintaining a biodiversity data collection has been a much-needed worldwide exercise for years, yet there is no single standard on how to do this. To make the most out of biodiversity data and to ensure that its use for environmental monitoring and conservation is easy and legal, the FP7-funded EU project EU BON published recommendations. These recommendations provide for consistent Europe-wide Data Publishing Guidelines and Recommendations in the EU BON Biodiversity Portal.

Contact: Dr. Willi Egloff
Pensoft Publishers

Public Release: 22-Mar-2016
ASAA's SleepHealth mobile study app grows along with Apple
Today, the American Sleep Apnea Association (ASAA) announced that its SleepHealth app takes advantage of improvements in Apple iOS 9.3 by being the first ResearchKit app to incorporate the new Night Shift mode into its study and wellness tool. Night Shift automatically shifts the colors in one's display to the warmer end of the spectrum in conjunction with sunset based on the user's time and location. In the morning, it returns the display to its regular settings.
American Sleep Apnea Association

Contact: Darrel Drobnich
American Sleep Apnea Association

Public Release: 22-Mar-2016
Molecular Biology and Evolution
MEGA evolutionary software re-engineered to handle today's big data demands
A Temple University-led research team has released a new version of their popular MEGA (Molecular Evolutionary Genomics Analysis) software, one of the most highly downloaded and widely used tools used by scientists worldwide to harness large-scale DNA sets for comparative studies.

Contact: Joe Caspermeyer
Molecular Biology and Evolution (Oxford University Press)

Public Release: 21-Mar-2016
Nature Reviews Genetics
Beyond DNA: TGen points the way to enhanced precision medicine with RNA sequencing
Researchers at the Translational Genomics Research Institute (TGen) are showing how genetic analysis using RNA sequencing can vastly enhance that understanding, providing doctors and their patients with more precise tools to target the underlying causes of disease, and help recommend the best course of action. Published today in the journal Nature Reviews Genetics, TGen scientists highlight the many advantages of using RNA-sequencing in the detection and management of everything from cancer to infectious diseases
Ben & Catherine Ivy Foundation of Scottsdale, National Center for Advancing Translational Sciences, Stand Up To Cancer-Melanoma Research Alliance Melanoma Dream Team Translational Cancer Research Grant

Contact: Steve Yozwiak
The Translational Genomics Research Institute

Public Release: 21-Mar-2016
Nature Methods
Supporting the bioimaging revolution
The rapid rise of high-resolution 3-D cellular imaging techniques in biology demands data solutions -- and EMBL is there to provide them.
Medical Research Council, Biotechnology and Biomedical Science Research Council, Wellcome Trust, EMBL

Contact: Mary Todd Bergman
European Molecular Biology Laboratory - European Bioinformatics Institute

Public Release: 21-Mar-2016
Top 50 most wanted fungi: New search function zooms in on the dark fungal diversity
There are many millions of undescribed fungi. As a result, public DNA sequence databases abound with fungal sequences that are unidentified even at the phylum level. Frustrated at this situation, an international group of researchers presents a search function to highlight the fungi we know the least about. The effort hopes to encourage community participation and speed up scientific progress in the enigmatic fungal kingdom. Their research is published in the open-access journal MycoKeys.

Contact: Dr. Henrik Nilsson
Pensoft Publishers

Public Release: 17-Mar-2016
Wrangler Supercomputer speeds through big data
A new kind of supercomputer called Wrangler is helping researchers speed through the bumpy terrain of big data and reach new discoveries, according to a special report at the Texas Advanced Computing Center. NSF-funded Wrangler is designed to be more user-friendly with a web-driven approach to high performance computing, including data analytics. The biologists, anthropologists, energy-efficiency experts, and astronomers profiled represent just a slice of the diverse community Wrangler supports.
National Science Foundation, US Department of Energy

Contact: Faith Singer-Villalobos
University of Texas at Austin, Texas Advanced Computing Center

Public Release: 17-Mar-2016
Optical Materials Express
New technique for rapidly killing bacteria using tiny gold disks and light
Researchers have developed a new technique for killing bacteria in seconds using highly porous gold nanodisks and light, according to a study published today in Optical Materials Express, a journal published by The Optical Society. The method could one day help hospitals treat some common infections without using antibiotics, which could help reduce the risk of spreading antibiotics resistance.

Contact: Rebecca Andersen
The Optical Society

Public Release: 17-Mar-2016
Calcium controls sleep duration in mice
University of Tokyo and RIKEN researchers have identified seven genes responsible for causing mice to stay awake or fall asleep based on a theoretical model of sleep and on experiments using 21 different genetically modified mice, some of which showed different sleep durations. Researchers hope that their research will contribute to the understanding and treatment of sleep disorders and associated neurodegenerative diseases.

Contact: Hiroki Ueda
University of Tokyo

Public Release: 11-Mar-2016
Citizen science project draws up the first oral microbiome map for the youth
In the year following its launch, this project has brought bioinformatics closer to society, and highlighted the importance of the microbiome, with the participation of over 4,000 individuals. The results of the scientific study have revealed an initial oral microbiome map of young people, pointing to significant differences according to their geographic location, dietary or lifestyle factors, such as smoking or owning a pet.
la Caixa Bank Foundation, Severo Ochoa Programme of Excellence, Spanish Ministry of Economy and Competitiveness

Contact: Laia Cendros
Center for Genomic Regulation

Public Release: 11-Mar-2016
Science Advances
Quality control for genetic sequencing
Genetic sequencing is in widespread use today, but until now has not been accurate enough to identify an antibody immune response. Now, thanks to a new control system based on genetic barcodes, the technique is far more reliable -- and ready for use in the development of vaccines and antibody drugs.

Contact: Dr. Sai Reddy
ETH Zurich

Public Release: 10-Mar-2016
Genome Biology and Evolution
Dramatically dynamic genomic evolution of a mighty mite
Sequencing and comparative analysis of the genome of the Western Orchard predatory mite has revealed intriguingly-extreme genomic evolutionary dynamics through an international research effort co-led by scientists from the University of Geneva and the SIB Swiss Institute of Bioinformatics.

Contact: Robert M. Waterhouse
Swiss Institute of Bioinformatics

Public Release: 10-Mar-2016
BMC Bioinformatics
Scientists developed a robust method for analysis of intestinal bacteria
A research group from Russia have proposed a new method for the comparison of microbiota (bacteria living in and on human body; metagenome) DNA sequences. The method makes it possible to more effectively and quickly solve the task of comparing samples and can be easily embedded in the data-analysis process of any metagenome study. The developed technique allows to investigate differences between bacterial communities in our organisms more efficient and accurate.

Contact: Valerii Roizen
Moscow Institute of Physics and Technology

Public Release: 10-Mar-2016
Nature Methods
Tracking the social networks of genes disrupted in complex diseases
Your personal risk of developing complex diseases such as diabetes, depression or cancer is influenced in part by genetic variants, that is, letters in your DNA sequence that differ between people. These variants disrupt networks of interacting genes in different tissues of your body, two studies published in Nature Methods and PLOS Computational Biology found.

Contact: Daniel Marbach
Swiss Institute of Bioinformatics

Showing releases 626-650 out of 952.

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