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Key: Meeting M      Journal J      Funder F

Showing releases 626-650 out of 947.

<< < 21 | 22 | 23 | 24 | 25 | 26 | 27 | 28 | 29 | 30 > >>

Public Release: 26-Oct-2015
Proceedings of the National Academy of Sciences
CRISPR/Cas9 used for rapid functional study of cancer-causing genes
A novel approach using the recently developed CRISP/Cas9 technique to switch off genes has been used for the first time to identify genes that cause liver cancer in adult mice. Rapid, scalable and flexible, this new method can identify novel cancer-causing genes, determine which combinations cause cancer and model development of cancer in adults. The team show that CRISPR/Cas9 can be used to induce and study liver cancer, the sixth most prevalent cancer worldwide.
German Cancer Consortium, Helmholtz Gemeinschaft

Contact: Samantha Wynne
Wellcome Trust Sanger Institute

Public Release: 26-Oct-2015
Twenty-three researchers recognized as EMBO Young Investigators
EMBO announced today the selection of 23 young researchers as EMBO Young Investigators. The scientists join a network of 365 current and past Young Investigators who represent some of the best young group leaders contributing to research in Europe and beyond.
European Molecular Biology Organization

Contact: Yvonne Kaul

Public Release: 26-Oct-2015
FDA approves new therapy for pancreatic cancer patients
Patients with advanced pancreatic cancer now have access to the new FDA approved drug, Onivyde, that produced significant overall survival rates in an international clinical study conducted in part by researchers at HonorHealth Research Institute and the Translational Genomics Research Institute.

Contact: Steve Yozwiak
The Translational Genomics Research Institute

Public Release: 23-Oct-2015
Proceedings of the National Academy of Sciences
A new algorithm to predict the dynamic language of proteins
Researchers have developed the first computational method based on evolutionary principles to predict the changes in shape that proteins experience to carry out their functions. This method is a step forward in the study of protein dynamics, of great importance for the design of drugs and the investigation of genetic diseases such as cancer. The work, published in the journal Proceedings of the National Academy of Sciences, was prepared by researchers at the CNIO and University College London.

Contact: Vanessa Pombo
Centro Nacional de Investigaciones Oncológicas (CNIO)

Public Release: 22-Oct-2015
The ties that bind: WPI researchers search for the hidden genetic code across species
When species as different as humans and yeast share common genetic elements, those snippets of DNA are likely to perform fundamental biological functions. The National Science Foundation has awarded Worcester Polytechnic Institute $768,000 to identify such elements across all known genomes of plants, animals, fungi, and other complex organisms to gain insight into the roles they play. A team led by Dmitry Korkin will conduct the search using mathematical algorithms and advanced computing technology.
National Science Foundation

Contact: Michael Cohen
Worcester Polytechnic Institute

Public Release: 22-Oct-2015
Acta Diabetologica
Simple test to detect diabetes risk after pregnancy
Gestational diabetes is one of the most common conditions that can occur during pregnancy. Although the symptoms generally disappear after delivery, women suffering from gestational diabetes are at increased risk of developing postpartum diabetes in the following years. Researchers at the Helmholtz Zentrum München have now developed an accurate method of predicting the probability of developing this progressive disease following childbirth. Their findings were published recently in 'Acta Diabetologica.'

Contact: Prof. Dr. Anette-Gabriele Ziegler
Helmholtz Zentrum München - German Research Center for Environmental Health

Public Release: 22-Oct-2015
New gene a key to fighting sepsis
Scientists have identified a gene that could potentially open the door for the development of new treatments of the lethal disease sepsis.

Contact: Professor Simon Foote
Australian National University

Public Release: 21-Oct-2015
The Auk: Ornithological Advances
Advances in genetic studies of birds are changing ornithology research
How do birds evolve over generations? How do different bird populations diverge into new species? Ornithologists have been asking these questions since the days of Darwin, but rapid advances in genetic sequencing techniques in the last few years have brought answers more in reach than ever.

Contact: Rebecca Heisman
American Ornithological Society Publications Office

Public Release: 20-Oct-2015
Molecular Cell
A new way to starve lung cancer?
Scientists have identified a new way to stop the growth of lung cancer cells, by blocking their ability to use alternative sources of nutrition. The discovery was made possible by identifying the metabolic programs used by cancer cells to fuel their growth. The findings point to possible new avenues for treating lung cancer, which is the second most common cancer and accounts for over one-quarter of all cancer-related deaths. The results of the study were published Oct. 15 in the journal Molecular Cell.

Contact: Cynthia Lee
McGill University

Public Release: 19-Oct-2015
Site of inflammatory bowel disease crucial
A groundbreaking study of more than 30,000 patients with inflammatory bowel disease has shown that genetic factors affect the location of the inflammation in the gut, with important implications for diagnosis and treatment of patients. The largest study of its kind, this research uncovered a genetic similarity between Crohn's disease and ulcerative colitis, suggesting they form a continuum of subtypes in the bowel. That genetic information could be used to inform treatment and reveal misdiagnoses.
National Association for Colitis and Crohn's disease, Wellcome Trust, Medical Research Council, Catherine McEwan Foundation, Peninsula College of Medicine and Dentistry, National Institute for Health Research, and others

Contact: Sam Wynne
Wellcome Trust Sanger Institute

Public Release: 19-Oct-2015
Proceedings of the National Academy of Sciences
Regrow a tooth? Fish -- yes; humans -- maybe some day
When a Lake Malawi cichlid loses a tooth, a new one drops neatly into place as a replacement. Why can't humans similarly regrow teeth lost to injury or disease?
NIH/National Institute of Dental and Craniofacial Research

Contact: John Toon
Georgia Institute of Technology

Public Release: 16-Oct-2015
Cancer Cell
Protein found in malaria could help stop cancer
Researchers at the Translational Genomics Research Institute joined an international team of scientists in discovering how a protein from malaria could some day help stop cancer.

Contact: Steve Yozwiak
The Translational Genomics Research Institute

Public Release: 16-Oct-2015
OMICS: A Journal of Integrative Biology
What can we learn from nutrigenomics testing?
There is insufficient scientific evidence to support the utility of commercially available nutrigenomics tests that claim to link genetic variants to dietary intake or nutrition-related disorders. While nutrigenomics remains a promising tool for advancing personalized medicine and healthcare, more research is needed before it can help guide health-related decisions, according to a study published in OMICS: A Journal of Integrative Biology.

Contact: Kathryn Ryan
Mary Ann Liebert, Inc./Genetic Engineering News

Public Release: 15-Oct-2015
$6.5 million grant may lead to disease-resistant cucurbits
A collaboration between horticulturists and bioinformaticists has received a $6.5 million USDA grant to identify genetic regions useful for breeding disease-resistant melons, squash and pumpkins. BTI researcher Zhangjun Fei will lead the bioinformatics portion of the project.
US Department of Agriculture

Contact: Patricia Waldron
Boyce Thompson Institute

Public Release: 15-Oct-2015
Mini DNA sequencer tests true
The MinION, a handheld DNA-sequencing device developed by Oxford Nanopore, has been tested and evaluated by an independent, international consortium coordinated by EMBL's European Bioinformatics Institute. The innovative device opens up new possibilities for using sequencing technology in the field, for example in tracking disease outbreaks, testing packaged food or the trafficking of protected species.
Wellcome Trust, Rosetrees Trust, Biotechnology and Biological Sciences Research Council, Canadian Institutes of Health Research, National Science Foundation, National Institutes of Health, NIH/National Human Genome Research Institute, and others

Contact: Mary Todd Bergman
European Molecular Biology Laboratory - European Bioinformatics Institute

Public Release: 15-Oct-2015
US neuroscientists call for creation of 'brain observatories'
What is the future of the BRAIN Initiative? This national White House Grand Challenge involving more than 100 laboratories in the United States has already made progress in establishing large-scale neuroscience goals and developing shared tools. And now in an Opinion paper publishing Oct. 15 in Neuron, leading American neuroscientists call for the next step: a coordinated national network of neurotechnology centers or 'brain observatories.'

Contact: Joseph Caputo
Cell Press

Public Release: 14-Oct-2015
Philosophical Transactions of the Royal Society A
Chemical microdroplet computers are easier to teach than to design
Scientists from the Institute of Physical Chemistry of the Polish Academy of Sciences in Warsaw in cooperation with the Institute of Physics of the PAS and the University of Jena have developed the concept of a simple chemical computer made of microdroplets capable of searching databases. Computer simulations, carried out on databases of malignant tumors, have confirmed the validity of the adopted new design strategy, which opens the door to the popularization of chemical methods of processing information.

Contact: Jerzy Górecki
Institute of Physical Chemistry of the Polish Academy of Sciences

Public Release: 14-Oct-2015
BMC Plant Biology
Could contaminated land actually be good for trees?
The very act of tolerating some forms of soil pollution may give trees an advantage in the natural world, says University of Montreal plant biologists. Their findings were published this week in BMC Plant Biology.
Genome Canada, Genome Québec

Contact: William Raillant-Clark
University of Montreal

Public Release: 13-Oct-2015
Manuscript at the click of a button
Data collection and analysis are at the core of modern research, and often take months or even years during which researchers remain uncredited for their contribution. A new plugin to a workflow previously developed by the Global Biodiversity Information Facility and Pensoft, and tested with datasets shared through GBIF and DataONE, now makes it possible to convert metadata into a manuscript for scholarly publications, with a click of a button.

Contact: Lyubomir Penev
Pensoft Publishers

Public Release: 13-Oct-2015
Molecular Biology and Evolution
A dominant evolutionary theme emerges to better predict clinical outcomes for cancer
In a study published in the early online edition of Molecular Biology and Evolution, authors Han Chen and Xionglei He have used a new computational approach to show that as tumors evolve, no matter what the tissue or cell type, a dominant theme has emerged. Those that are trending toward a more primitive, or embryonic stem cell (ESC) state -- have a worse clinical outcome.

Contact: Joe Caspermeyer
Molecular Biology and Evolution (Oxford University Press)

Public Release: 12-Oct-2015
NIH grants $3.7 million to develop new system for understanding the 3-D genome
A five-year, $3.7 million grant was awarded to a team led by Professor Yijun Ruan, Ph.D., of The Jackson Laboratory for Genomic Medicine to fund research into how the human genome is organized in the nucleus of the cell.
NIH/National Institute of Diabetes and Digestive and Kidney Diseases

Contact: Joyce Peterson
Jackson Laboratory

Public Release: 12-Oct-2015
Nature Medicine
Scientists uncover 4 different types of bowel cancer
Bowel cancer can be divided up into four distinct diseases, each with its own set of biological characteristics, a major new study reports. The research could allow doctors to treat each type of bowel cancer differently - and drive the design of distinct sets of targeted drugs for each type.
Institute of Cancer Research London, NIHR Biomedical Research Centre at the Royal Marsden, Institute of Cancer Research

Contact: Claire Hastings
Institute of Cancer Research

Public Release: 9-Oct-2015
Genome Biology
A better way to read the genome
UConn genomicists have sequenced the RNA of the most complicated gene known in nature, using a hand-held sequencer no bigger than a cell phone. The researchers teamed up with Oxford Nanopore Technologies to show that the company's MinION nanopore sequencer can sequence genes faster, better, and at a much lower cost than the standard technology. Brenton Graveley will discuss the research at the Oxford Nanopore MinION Community Meeting at New York Genome Center Dec. 3.
National Institutes of Health

Contact: Kim Krieger
University of Connecticut

Public Release: 9-Oct-2015
American Society of Human Genetics 2015 Annual Meeting
Researchers study costs of integrating genetic sequencing into clinical care
Integrating whole genome sequencing into primary care and heart disease care is unlikely to substantially increase the costs of health care utilization and follow-up tests, according to research presented at the American Society of Human Genetics 2015 Annual Meeting in Baltimore. On average, patients whose genomes were sequenced incurred a cost of $719 in follow-up tests and care over the following year, including out-of-pocket expenses, while standard treatment and follow-up averaged $430 per patient.

Contact: Nalini Padmanabhan
American Society of Human Genetics

Public Release: 8-Oct-2015
American Journal of Human Genetics
Genetic variation is key to fighting viruses
Using a genome-wide association study, EPFL scientists have identified subtle genetic changes that can cause substantial differences to how we fight viral infections.
Max Planck Society, Swiss National Science Foundation

Contact: Nik Papageorgiou
Ecole Polytechnique Fédérale de Lausanne

Showing releases 626-650 out of 947.

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