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Key: Meeting M      Journal J      Funder F

Showing releases 701-725 out of 969.

<< < 24 | 25 | 26 | 27 | 28 | 29 | 30 | 31 | 32 | 33 > >>

Public Release: 11-Nov-2015
CWRU researchers building digital pathology tools to predict cancer outcomes
Case Western Reserve University researchers have been awarded two grants totaling $3.16 million from the National Institutes of Health to create analytic software for managing, annotating, sharing and analyzing digital pathology imaging data. They will start by focusing on tools for quantifying tissue-based biomarkers and disease patterns on digital images of prostate and breast cancer biopsy.
National Institutes of Health

Contact: Kevin Mayhood
Case Western Reserve University

Public Release: 11-Nov-2015
PLOS Biology
Simple errors limit scientific scrutiny
Researchers have found more than half of the public datasets provided with scientific papers are incomplete, which prevents reproducibility tests and follow-up studies. However, slight improvements to research practices could make a big difference.

Contact: Loeske Kruuk
Australian National University

Public Release: 9-Nov-2015
Nature Methods
New method IDs up to twice as many proteins and peptides in mass spectrometry data
An team of researchers developed a method that identifies up to twice as many proteins and peptides in mass spectrometry data than conventional approaches. The method can be applied to a range of fields, including clinical settings and fundamental biology research for cancer and other diseases. The key to the method's improved performance is its ability to compare data to so-called spectral libraries -- a pattern-matching exercise -- rather than individual spectra or a database of sequences.
National Institutes of Health

Contact: Ioana Patringenaru
University of California - San Diego

Public Release: 9-Nov-2015
Developmental Cell
Unpacking embryonic pluripotency
A map of gene expression in mouse and marmoset embryos defines common origins of pluripotency in mammalian development. The study identifies specific pathways critical for early lineage segregation in the primate. The findings have implications for optimising methods to isolate pluripotent stem cells, to reprogram cells to pluripotency, or to improve human embryo culture.
Wellcome Trust, Biotechnology and Biological Sciences Research Council, Medical Research Council, Louis Jeantet Foundation, European Molecular Biology Laboratory

Contact: Mary Todd Bergman
European Molecular Biology Laboratory - European Bioinformatics Institute

Public Release: 9-Nov-2015
Southeastern/Southwestern Regional Meeting of the American Chemical Society
St. Jude and TSRI scientists help launch Human Dark Proteome Initiative
Group will focus on advancing research on intrinsically disordered proteins to better understand catastrophic diseases.

Contact: Madeline McCurry-Schmidt
Scripps Research Institute

Public Release: 6-Nov-2015
TGen will lead international SU2C dream team to tackle deadly pancreatic cancer
The Phoenix-based Translational Genomics Research Institute (TGen) will lead an international Stand Up To Cancer (SU2C) Dream Team of top cancer researchers in a $12 million effort to double the survival of patients with pancreatic cancer, the fourth leading cause of cancer death in the US.
Cancer Research UK, Lustgarten Foundation, SU2C

Contact: Steve Yozwiak
The Translational Genomics Research Institute

Public Release: 6-Nov-2015
Angewandte Chemie International Edition
First synthetic model of bacteria outer membrane
An international collaboration led by scientists from Newcastle University, UK, and the Rutherford Appleton Laboratory has produced the first in vitro model of the outer membrane of the bacteria E. coli providing a tool for developing new antibiotics and other drugs.
Wellcome Trust

Contact: Karen Bidewell
Newcastle University

Public Release: 6-Nov-2015
Molecular Systems Biology
Gut microbiota regulates antioxidant metabolism
A recently published study shows that gut microbiota regulates the glutathione and amino acid metabolism of the host. Glutathione is a key antioxidant, found in every cell in our body. Deficiency of glutathione contributes to oxidative stress, which plays a major role in several lifestyle diseases.

Contact: Johanna Wilde
Chalmers University of Technology

Public Release: 6-Nov-2015
Nature Communications
Neurodermatitis genes influence other allergies
There's a typical 'career' for some allergic people, and it starts very early on the skin: babies develop atopic dermatitis, food allergies may follow, then comes asthma and later on hay fever. A group of scientists led by Ingo Marenholz and Young-Ae Lee at the Max Delbrück Center for Molecular Medicine in the Helmholtz Association, working with colleagues from several institutions, has now identified seven genetic risk loci for this course of disease.

Contact: Josef Zens
Max Delbrück Center for Molecular Medicine in the Helmholtz Association

Public Release: 5-Nov-2015
New from CSHLPress, an indispensable bench-side handbook for biologists using R
'Using R at the Bench: Step-by-Step Data Analytics for Biologists,' from Cold Spring Harbor Laboratory Press, is a convenient bench-side handbook for biologists, designed as a handy reference guide for elementary and intermediate statistical analyses using the free/public software package known as 'R.' It is both a simple refresher as well as an overview, and is available in both spiral bound hardcover and eBook formats.

Contact: Robert Redmond
Cold Spring Harbor Laboratory

Public Release: 4-Nov-2015
Science Translational Medicine
More than skin deep
Most products on the market today that are used to treat skin problems target the effects of the disease or wound such as inflammation, which can prolong the healing process and result in scarring. However, LSU Assistant Professor Wei Xu and collaborators at Northwestern University discovered a new way to prevent inflammation and to speed up the skin's healing process.

Contact: Alison Satake
Louisiana State University

Public Release: 4-Nov-2015
Nature Communications
'Liquid biopsy' promotes precision medicine by tracking patient's cancer
A team of researchers, including scientists from the Translational Genomics Research Institute (TGen), has reported that analyzing circulating tumor DNA (ctDNA) can track how a patient's cancer evolves and responds to treatment. In a study published today in Nature Communications, Dr. Muhammed Murtaza of TGen and Mayo Clinic, and colleagues, describe an extensive comparison between biopsy results and analysis of ctDNA in a patient with breast cancer.

Contact: Steve Yozwiak
The Translational Genomics Research Institute

Public Release: 3-Nov-2015
Grant establishes center for 3-D structure and physics of the genome at UMMS
The University of Massachusetts Medical School has been awarded a five-year, $15 million grant from the National Institutes of Medicine Common Fund to establish the Center for 3-D Structure and Physics of the Genome. The center is part of the NIH's 4-D Nucleome Program, an interdisciplinary effort comprising 29 research teams across the country with the goal of mapping the three-dimensional architecture of the human genome and how this organization changes over time -- the fourth dimension.
National Institutes of Medicine Common Fund, NIH/National Cancer Institute, NIH/National Institute of Diabetes and Digestive and Kidney Diseases, NIH/National Institute of Biomedical Imaging and Bioengineering, NIH/National Heart, Lung and Blood Institute

Contact: Jim Fessenden
University of Massachusetts Medical School

Public Release: 3-Nov-2015
Chemical Research in Toxicology
New computational approach to predicting adverse drug reactions with higher confidence
A new integrated computational method helps predicting adverse drug reaction -- which are often lethal -- more reliably than with traditional computing methods. This improved ability to foresee the possible adverse effects of drugs may entail saving many lives in the future. The study is being conducted by researchers from IMIM (Hospital del Mar Medical Research Institute), University Pompeu Fabra, and the company Chemotargets, within the framework of the European eTOX project.

Contact: Marta Calsina Freixas
IMIM (Hospital del Mar Medical Research Institute)

Public Release: 2-Nov-2015
Nature Methods
Tissue cartography
Today's state-of-the-art optical microscopes produce voluminous three-dimensional data sets that are difficult to analyze. Now, two postdoctoral scholars from UC Santa Barbara's Kavli Institute for Theoretical Physics have developed a means of reducing data size and processing by orders of magnitude.

Contact: Julie Cohen
University of California - Santa Barbara

Public Release: 30-Oct-2015
New computational strategy finds brain tumor-shrinking molecules
Patients with glioblastoma, a type of malignant brain tumor, usually survive fewer than 15 months following diagnosis. Since there are no effective treatments for the deadly disease, University of California, San Diego researchers developed a new computational strategy to search for molecules that could be developed into glioblastoma drugs. In mouse models of human glioblastoma, one molecule they found shrank the average tumor size by half. The study is published October 30 by Oncotarget.
NIH/National Institutes of Health, Voices Against Brain Cancer Foundation, Christopher and Bronwen Gleeson Family Trust, American Brain Tumor Association Drug Discovery Grant

Contact: Heather Buschman
University of California - San Diego

Public Release: 30-Oct-2015
Nucleic Acids Research
Genetics of cancer cells: Computational models to sort out the chaos
Scientists of the Luxembourg Centre for Systems Biomedicine of the University of Luxembourg have developed a method for analysing the genome of cancer cells more precisely than ever before. The team led by Prof. Antonio del Sol, head of the research group Computational Biology, is employing bioinformatics: Using novel computing processes, the researchers have created models of the genome of cancer cells based on known changes to the genome. These models are useful for determining the structure of DNA in tumors

Contact: Sabine Mosch
University of Luxembourg

Public Release: 29-Oct-2015
UC San Diego unveils campus-wide microbiome and microbial sciences initiative
University of California, San Diego Chancellor Pradeep K. Khosla announces the launch of the UC San Diego Microbiome and Microbial Sciences Initiative, a concerted research and education effort that leverages the university's strengths in science, medicine, engineering and the humanities to produce a detailed understanding of microbiomes -- distinct constellations of bacteria, viruses and other microorganisms that live within and around us -- and methods for manipulating them for the benefit of human health and the environment.

Contact: Heather Buschman
University of California - San Diego

Public Release: 29-Oct-2015
Streamlined import of specimen & occurrence records into taxonomic manuscripts
Substantial amount of documented occurrence (specimen and observational) records is awaiting publication stored in repositories and data indexing platforms, such as GBIF, BOLD systems, and iDigBio. In order to streamline the authoring process, save taxonomists time, and provide a workflow for peer-review and quality checks, Pensoft has introduced an innovative feature that makes it possible to easily import occurrence records into a taxonomic manuscript.

Contact: Lyubomir Penev
Pensoft Publishers

Public Release: 29-Oct-2015
Space station investigation goes with the flow
The investigation's success could help scientists develop countermeasures that will influence the future of human spaceflight on long-duration missions.

Contact: Rachel Hobson
NASA/Johnson Space Center

Public Release: 29-Oct-2015
PLOS Computational Biology
'Ensemble' modeling could lead to better flu forecasts
By combining data from a variety of non-traditional sources, a research team led by computational epidemiologists at Boston Children's Hospital has developed predictive models of flu-like activity that provide robust real-time estimates (a.k.a. 'now-casts') of flu activity and accurate forecasts of flu-like illness levels up to three weeks into the future.

Contact: Mauricio Santillana

Public Release: 28-Oct-2015
Hot processor speeds up UK genome analysis
The Genome Analysis Centre is the first Institute in the UK to deploy a new bioinformatics processor called DRAGEN, which dramatically reduces genomic pipeline run times from hours to minutes. This collaboration between Edico Genome and TGAC resulted in the first adaptation of the DRAGEN technology for the analysis of non-human genomes as part of the Institute's endeavors to sequence the DNA of plant, animal and microbial species to promote a sustainable bioeconomy.

Contact: Hayley London
Earlham Institute

Public Release: 26-Oct-2015
Proceedings of the National Academy of Sciences
CRISPR/Cas9 used for rapid functional study of cancer-causing genes
A novel approach using the recently developed CRISP/Cas9 technique to switch off genes has been used for the first time to identify genes that cause liver cancer in adult mice. Rapid, scalable and flexible, this new method can identify novel cancer-causing genes, determine which combinations cause cancer and model development of cancer in adults. The team show that CRISPR/Cas9 can be used to induce and study liver cancer, the sixth most prevalent cancer worldwide.
German Cancer Consortium, Helmholtz Gemeinschaft

Contact: Samantha Wynne
Wellcome Trust Sanger Institute

Public Release: 26-Oct-2015
Twenty-three researchers recognized as EMBO Young Investigators
EMBO announced today the selection of 23 young researchers as EMBO Young Investigators. The scientists join a network of 365 current and past Young Investigators who represent some of the best young group leaders contributing to research in Europe and beyond.
European Molecular Biology Organization

Contact: Yvonne Kaul

Public Release: 26-Oct-2015
FDA approves new therapy for pancreatic cancer patients
Patients with advanced pancreatic cancer now have access to the new FDA approved drug, Onivyde, that produced significant overall survival rates in an international clinical study conducted in part by researchers at HonorHealth Research Institute and the Translational Genomics Research Institute.

Contact: Steve Yozwiak
The Translational Genomics Research Institute

Showing releases 701-725 out of 969.

<< < 24 | 25 | 26 | 27 | 28 | 29 | 30 | 31 | 32 | 33 > >>