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Key: Meeting M      Journal J      Funder F

Showing releases 726-750 out of 919.

<< < 25 | 26 | 27 | 28 | 29 | 30 | 31 | 32 | 33 | 34 > >>

Public Release: 16-Apr-2015
Molecular Systems Biology
Systems-wide genetic study of blood pressure regulation in the Framingham Heart Study
A genetic investigation of individuals in the Framingham Heart Study may prove useful to identify novel targets for the prevention or treatment of high blood pressure. The study, which takes a close look at networks of blood pressure-related genes, is published in the journal Molecular Systems Biology.

Contact: Barry Whyte

Public Release: 15-Apr-2015
International Journal of Epidemiology
Paternal sperm may hold clues to autism
In a small study, Johns Hopkins researchers found that DNA from the sperm of men whose children had early signs of autism shows distinct patterns of regulatory tags that could contribute to the condition.
NIH/National Institute of Environmental Health Sciences, Autism Speaks

Contact: Catherine Kolf
Johns Hopkins Medicine

Public Release: 15-Apr-2015
New method increases accuracy of ovarian cancer prognosis and diagnosis
University of Utah scientists have uncovered patterns of DNA anomalies that predict a woman's outcome significantly better than tumor stage. In addition, these patterns are the first known indicator of how well a woman will respond to platinum therapy. Published in the journal PLOS ONE, the patterns were discovered by using a new mathematical technique in the analysis of DNA profiles from the Cancer Genome Atlas, a national database containing data from hundreds of ovarian cancer patients.
Utah Science, Technology, and Research Initiative, NIH/National Human Genome Research Institute, National Science Foundation

Contact: Julie Kiefer
University of Utah Health Sciences

Public Release: 14-Apr-2015
Nature Scientific Data
New ORNL, NC State and LanzaTech DNA dataset is potent, accessible tool
Scientists focused on producing biofuels more efficiently have a new powerful dataset to help them study the DNA of microbes that fuel bioconversion and other processes.

Contact: Ron Walli
DOE/Oak Ridge National Laboratory

Public Release: 14-Apr-2015
The Journal of Alternative and Complementary Medicine
Antimalarial tea -- from herbal remedy to licensed phytomedicine
Malaria is a critical health problem in West Africa, where traditional medicine is commonly used alongside modern healthcare practices. An herbal remedy derived from the roots of a weed, which was traditionally used to alleviate malarial symptoms, was combined with leaves and aerial portions from two other plants with antimalarial activity, formulated as a tea, and eventually licensed and sold as an antimalarial phytomedicine.

Contact: Kathryn Ryan
Mary Ann Liebert, Inc./Genetic Engineering News

Public Release: 14-Apr-2015
The Astrophysical Journal
Search for advanced civilizations beyond Earth finds nothing obvious in 100,000 galaxies
After searching 100,000 galaxies for signs of highly advanced life, a team of scientists using observations from NASA's WISE satellite has found no evidence of advanced civilizations there. The idea behind the research is that, if an entire galaxy had been colonized by an advanced spacefaring civilization, the energy produced by that civilization's technologies would be detectable in mid-infrared wavelengths. The research team's first paper about its results will be published on April 15, 2015.
John Templeton Foundation

Contact: Barbara K. Kennedy
Penn State

Public Release: 14-Apr-2015
Molecular Biology and Evolution
Most comprehensive study to date reveals evolutionary history of citrus
Citrus fruits -- delectable oranges, lemons, limes, kumquats and grapefruits -- are among the most important commercially cultivated fruit trees in the world, yet little is known of the origin of the citrus species and the history of its domestication. Now, Jaoquin Dopazo et al., have performed the largest and most detailed genomic analysis on 30 species of citrus, representing 34 citrus genotypes, and used chloroplast genomic data to reconstruct its evolutionary history.

Contact: Joe Caspermeyer
Molecular Biology and Evolution (Oxford University Press)

Public Release: 13-Apr-2015
Proceedings of the National Academy of Sciences
X-ray ptychography, fluorescence microscopy combo sheds new light on trace elements
Scientists have developed a new approach that combines ptychographic X-ray imaging and fluorescence microscopy to study the important role trace elements play in biological functions on hydrated cells.
National Institutes of Health, US Department of Energy, National Center for Research Resources

Contact: Tona Kunz
DOE/Argonne National Laboratory

Public Release: 10-Apr-2015
AZ Business magazine picks TGen's Dr. Daniel D. Von Hoff as 2015 Researcher of the Year
AZ Business magazine has named Dr. Daniel D. Von Hoff of the Translational Genomics Research Institute (TGen) as its 2015 Researcher of the Year. Dr. Von Hoff, M.D., TGen's Distinguished Professor and Physician-In-Chief, directs clinical trials at the Virginia G. Piper Cancer Center Clinical Trials at HonorHealth that translates TGen research discoveries into new treatments for patients.

Contact: Steve Yozwiak
The Translational Genomics Research Institute

Public Release: 9-Apr-2015
Editing HIV out of our genome with CRISPR
In an attempt to render latent HIV completely harmless, researchers at the University of Massachusetts Medical School are using Cas9/CRISPR, a powerful gene editing tool, to develop a novel technology that can potentially cut the DNA of the latent virus out of an infected cell.
NIH/National Institute of Allergy and Infectious Diseases

Contact: Jim Fessenden
University of Massachusetts Medical School

Public Release: 9-Apr-2015
Molecular Genetics & Genomic Medicine
TGen finds likely genetic source of muscle weakness in 6 previously undiagnosed children
TGen scientists, using state-of-the-art genetic technology, have discovered the likely cause of a child's rare type of severe muscle weakness. The child was one of six cases in which TGen sequenced -- or decoded -- the genes of patients with Neuromuscular Disease and was then able to identify the genetic source, or likely genetic source, of each child's symptoms, according to a study published April 8 in the journal Molecular Genetics & Genomic Medicine.
Muscular Dystrophy Association, Flinn Foundation, Helios Education Foundation, Freeport-McMoRan Copper & Gold Foundation, and Arizona Biomedical Research Commission

Contact: Steve Yozwiak
The Translational Genomics Research Institute

Public Release: 9-Apr-2015
NSF brings together UT Dallas computer scientists, industry for new tech hub
UT Dallas computer scientists hope that funding from the National Science Foundation to create an Industry/University Cooperative Research Center will help the Dallas area become a research hub for technology that enhances human abilities.
National Science Foundation

Contact: LaKisha Ladson
University of Texas at Dallas

Public Release: 9-Apr-2015
Nature Communications
Epigenomic changes play an important role during the progression of melanoma
KU Leuven researchers have zeroed in on what makes cancer cells in melanoma so aggressive. They also succeeded in taming the effect in cell cultures. Melanoma, a type of skin cancer, is notoriously quick to metastasize and responds poorly to existing cancer treatments. In their study, published in Nature Communications, the researchers report a significant step forward in the characterization and potential treatment of melanoma.

Contact: Katrien Bollen
KU Leuven

Public Release: 8-Apr-2015
Improved understanding of protein complex offers insight into DNA replication initiation mechanism basics
A clearer understanding of the origin recognition complex -- a protein complex that directs DNA replication -- through its crystal structure offers new insight into fundamental mechanisms of DNA replication initiation. This will also provide insight into how ORC may be compromised in a subset of patients with Meier-Gorlin syndrome, a form of dwarfism in humans.
National Institutes of Health, US Department of Energy

Contact: Tona Kunz
DOE/Argonne National Laboratory

Public Release: 8-Apr-2015
Hidden burden: Most people carry recessive disease mutations
Humans carry an average of one to two mutations per person that can cause severe genetic disorders or prenatal death when two copies of the same mutation are inherited, according to estimates published today in the journal Genetics. The new numbers were made possible by a long-term collaboration between medical researchers and a unique community that has maintained detailed family histories for many generations.

Contact: Cristy Gelling
Genetics Society of America

Public Release: 8-Apr-2015
Journal of the National Cancer Institute
Genetic screening could improve breast cancer prevention
A test for a wide range of genetic risk factors could improve doctors' ability to work out which women are at increased risk of developing breast cancer, a major study of more than 65,000 women has shown. Improving the accuracy of risk analysis using genetic screening could guide breast cancer prevention in several ways -- for instance by offering high-risk women increased monitoring, personalized advice and preventative therapies.
Cancer Research UK, European Union, Breakthrough Breast Cancer, National Institutes of Health

Contact: Henry French
Institute of Cancer Research

Public Release: 7-Apr-2015
Human Genome Variation
A better biomarker to predict cetuximab response in CRC patients
Scientists at Insilico Medicine Inc. and Champions Oncology Inc. have successfully demonstrated a method to predict response to cetuximab in patients with colorectal cancer using OncoFinder pathway activation strength. The study identified a novel prognostic marker in colorectal cancer treated with cetuximab.

Contact: Qingsong Zhu
InSilico Medicine, Inc.

Public Release: 7-Apr-2015
Seena Magowitz Foundation funds TGen's zebrafish studies of pancreatic cancer
Today, scientists at the Translational Genomics Research Institute (TGen) are using zebrafish to accelerate investigations of pancreatic cancer, the nation's fourth-leading cause of cancer-related death. The studies are funded by the Scottsdale, Arizona-based Seena Magowitz Foundation. The amount of the funding was not disclosed.
Seena Magowitz Foundation

Contact: Steve Yozwiak
The Translational Genomics Research Institute

Public Release: 6-Apr-2015
ROIS collaboration on Data Centric Science
ROIS based in Tokyo signed MoUs on Data Centric Science research collaboration with European organizations, CSC -- IT Center for Science, Finland, DSI and EUDAT. The MoUs were signed on Feb. 25-26 in Tokyo, and are expected to form the basis of further collaboration between the parties.
Research Organization of Information and Systems

Contact: Ms. Rue Ikeya
Research Organization of Information and Systems

Public Release: 6-Apr-2015
Cancer Biotherapy and Radiopharmaceuticals
Can cancer vaccines prolong survival?
Therapeutic anti-cancer vaccines developed to treat metastatic disease such as advanced prostate cancer or melanoma rarely have a noticeable effect on the tumor but have been associated with a statistically significant increase in patient survival. Robert O. Dillman, M.D., NeoStem Inc., asserts that 'overall survival' rather than 'progression-free survival' should be the gold standard for evaluating the efficacy of cancer vaccines in clinical trials, in a provocative new article published in Cancer Biotherapy and Radiopharmaceuticals.

Contact: Kathryn Ryan
Mary Ann Liebert, Inc./Genetic Engineering News

Public Release: 2-Apr-2015
Journal of Applied Ecology
Bridging the gap between biodiversity data and policy reporting needs
Reporting under policy instruments to inform on the trends in biodiversity requires information from a range of different elements of biodiversity, from genetically viable populations to the structure of ecosystems. A new research funded by the EU FP7 project EU BON looks into the Essential Biodiversity Variables as an analytic framework to identify ways in which gaps between biodiversity data and policy reporting needs could be bridged.

Contact: Dr. Ilse Geijzendorffer
Pensoft Publishers

Public Release: 1-Apr-2015
Genome Research
Longer DNA fragments reveal rare species diversity
A challenge in metagenomics is that the more commonly used sequencing machines generate data in short lengths, while short-read assemblers may not be able to distinguish among multiple occurrences of the same or similar sequences, making it difficult to identify all the members in a microbial community. In the April 2015 issue of Genome Research, a team including DOE JGI researchers compared two ways of using next generation Illumina sequencing machines to help with this.
DOE/Office of Science

Contact: David Gilbert
DOE/Joint Genome Institute

Public Release: 1-Apr-2015
Scientists drill down to genetic root of prostate tumor development
Scientists have revealed the root of prostate cancers in individual men, discovering that despite huge genetic variety between tumors they also share common gene faults -- insight that could offer new treatment hopes.

Contact: Emily Head
Cancer Research UK

Public Release: 31-Mar-2015
Applications in Plant Sciences
Simplifying SNP discovery in the cotton genome
Researchers have developed a strategy that simplifies the discovery of useful single-nucleotide polymorphisms within the complex cotton genome. This method, recently published in Applications in Plant Sciences, will be useful for marker-assisted selection, linkage and QTL mapping, and genetic diversity studies. It has the added benefit of being applicable to other economically important allotetraploid species, including the brassicas, and can be extended to species that do not currently have a reference genome.
Cotton Incorporated Fellowship

Contact: Beth Parada
Botanical Society of America

Public Release: 31-Mar-2015
Four centers in Spain join forces to bridge the gap between research and clinical practice
Today, four centers in Barcelona jointly launch a program that seeks to offer advanced research training for physicians and to strengthen the collaboration between basic research centers and hospitals.

Contact: Laia Cendrós
Center for Genomic Regulation

Showing releases 726-750 out of 919.

<< < 25 | 26 | 27 | 28 | 29 | 30 | 31 | 32 | 33 | 34 > >>