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Disease in the Developing World

News Releases

Key: Meeting M      Journal J      Funder F

Showing releases 676-700 out of 1335.

<< < 23 | 24 | 25 | 26 | 27 | 28 | 29 | 30 | 31 | 32 > >>

Public Release: 8-Aug-2016
Nature Microbiology
TSRI scientists pinpoint Ebola's weak spots
Scientists at The Scripps Research Institute now have a high-resolution view of exactly how the experimental therapy ZMapp targets Ebola virus. The new study is also the first to show how an antibody in the ZMapp 'drug cocktail' targets a second Ebola virus protein, called sGP, whose vulnerable spots had previously been unknown.
NIH/National Institute of Allergy and Infectious Diseases, National Science Foundation

Contact: Madeline McCurry-Schmidt
Scripps Research Institute

Public Release: 8-Aug-2016
BMC Public Health
HIV stigma influenced by perceptions of masculinity, study reveals
Whether an HIV-positive man has met cultural expectations of masculinity might impact how much stigma he experiences, according to a new study from Binghamton University, State University of New York.

Contact: Titilayo Okoror
Binghamton University

Public Release: 8-Aug-2016
A single compound could treat 3 parasitic diseases
Scientists have identified a compound that can kill the parasites responsible for three neglected diseases: Chagas disease, leishmaniasis and sleeping sickness.
Wellcome Trust, National Institutes of Health

Contact: Hannah Isom
Wellcome Trust

Public Release: 8-Aug-2016
New drugs hope to fight neglected tropical diseases
Scientists say they are a step closer to providing effective treatments for three 'neglected' diseases after making a chemical which can kill the parasites that cause the illnesses.
Wellcome Trust

Contact: Saskia Angenent
University of York

Public Release: 5-Aug-2016
University of Maryland School of Medicine to take part in landmark Zika vaccine study
The Center for Vaccine Development at the University of Maryland School of Medicine's Institute for Global Health has been chosen as one of three study sites in a human safety trial of a new Zika vaccine. The early-stage study will evaluate the experimental vaccine's safety and ability to generate an immune system response in participants.

Contact: David Kohn
University of Maryland School of Medicine

Public Release: 4-Aug-2016
PLOS Neglected Tropical Diseases
New research points to novel approach to tackling Ascaris roundworm
Scientists have shed new light on Ascaris infection, which affects 1 billion people worldwide. Targeting specific liver proteins may offer new preventative options against an infection that kills around 60.000 people each year.

Contact: Thomas Deane
Trinity College Dublin

Public Release: 4-Aug-2016
PLOS Neglected Tropical Diseases
Susceptibility and resistance to the Ascaris round worm which infects 1 billion people
Approximately one billion people worldwide are estimated to be infected with the roundworm Ascaris lumbricoides, an intestinal parasite of humans. Some of them, especially children who carry high parasite loads, suffer from severe health consequences, including growth retardation and impaired cognitive development. A study published in PLOS NTDs examines the difference between mice that are susceptible to Ascaris infection and those that are resistant.
MU Department of Biology, TCD Department of Zoology, Welcome Trust

Contact: James Carolan

Public Release: 3-Aug-2016
Europhysics Letters
Contagion in popular places: From Zika to political extremism
The alert is out and South Floridians are taking heed. With the Centers for Disease Control and Prevention issuing a warning for visitors and locals to avoid a neighborhood in Miami after more than a dozen individuals contracted Zika, a team of University of Miami researchers have presented a new study that shows how the flow of visitors through a popular place, such as the affected Wynwood area of Miami, determines the eventual severity and duration of such an outbreak.

Contact: Deserae del Campo
University of Miami

Public Release: 3-Aug-2016
HIV/AIDS: Filarial worm infections double the risk of infection
Since the start of the HIV epidemic, there have been speculations as to why HIV and the immunodeficiency syndrome it causes have spread so much more in Africa than in other countries around the world. Scientists from the German Center for Infection Research (DZIF) have now, for the first time, confirmed one reason for this: in a cohort study conducted in Tanzania, they discovered that an infection with the filarial nematode Wuchereria bancrofti increases the risk of HIV infection by two to three fold.

Contact: Michael Hoelscher
German Center for Infection Research

Public Release: 2-Aug-2016
Treatment strategy under development has 2 arms to get a secure grip on cancer
Scientists have engineered a sort of biological barbell that can get inside cancer cells and do damage to two proteins that work independently and together to enable cancer's survival and spread.
US Department of Defense, NIH/National Cancer Institute

Contact: Toni Baker
Medical College of Georgia at Augusta University

Public Release: 2-Aug-2016
Lancet Global Health
Rapid bacterial infection test reduces antibiotic use
A trial of a 5-minute test at ten primary care centres in Vietnam reduced antibiotic use for respiratory infections. The rapid test detects C-reactive protein (CRP), a marker of infections caused by bacteria, in patients' blood: low CRP is suggestive of viral infection where antibiotic treatment is not required.
Wellcome Trust, Global Antibiotic Resistance Partnership,Center for Disease Dynamics, Economics & Policy, Bill & Melinda Gates Foundation

Contact: Katrina Lawson
University of Oxford

Public Release: 2-Aug-2016
Journal of The Royal Society Interface
Research targets number one killer of under-5s
Oxford researchers are developing a tool to make it much easier and cheaper to diagnose pneumonia -- the number one killer of children under 5. Currently, diagnosis requires X-ray and microbiology lab facilities -- unavailable in many areas of the world.
Engineering and Physical Sciences Research Council, Research Councils UK Digital Economy Programme,Wellcome Trust

Contact: Tom Calver
University of Oxford

Public Release: 2-Aug-2016
PLOS Medicine
Collateral harm: The impact of Ebola and related fears on facility-based child deliveries
The first known household survey examining the collateral harm to pregnancy services in areas affected by the West African Ebola epidemic suggests a significant slide backwards in child and maternal health. The study, conducted in Liberia, points to the deep disruptions caused by the Ebola epidemic -- even in parts of the country with relatively limited transmission.

Contact: Karen Teber
Georgetown University Medical Center

Public Release: 1-Aug-2016
Journal of Antimicrobial Chemotherapy
New anti-HIV medication provides protection for women and infants
Each year, 1.5 million women living with HIV become pregnant. Without effective treatment, up to 45 percent of HIV-infected mothers will transmit the virus to their child, usually through breastfeeding. In an effort to prevent HIV transmission to women and their children, researchers from the University of North Carolina at Chapel Hill demonstrated the effectiveness of a new anti-HIV medication, EFdA, in pre-clinical animal models.
National Institutes of Health

Contact: Morag MacLachlan
University of North Carolina Health Care

Public Release: 1-Aug-2016
Journal of Experimental Medicine
New study finds CD4 T-Cell and Blimp-1 protein critical to toxoplasmosis regulation
Researchers from the George Washington University published in the Journal of Experimental Medicine finding a way to regulate chronic toxoplasmosis, one of the most common parasitic diseases worldwide. This research also has important implications for cancer.
National Institutes for Health

Contact: Lisa Anderson
George Washington University

Public Release: 1-Aug-2016
Applied and Environmental Microbiology
Green monkeys acquired Staphylococcus aureus from humans
Already it's known that many deadly diseases that afflict humans were originally acquired through contact with animals. However new research from the University of Warwick shows that pathogens can also jump the species barrier to move from humans to animals.

Contact: Nicola Jones
University of Warwick

Public Release: 1-Aug-2016
PLOS Pathogens
Griffith scientists unlock the 'Malaria box'
A 'Malaria Box' that could hold the answer to discovering new drugs to treat tropical diseases and cancer has been created for researchers around the world.

Contact: Stephanie Bedo
Griffith University

Public Release: 29-Jul-2016
Cell Reports
Zika infection is caused by one virus serotype, NIH study finds
Vaccination against a single strain of Zika virus should be sufficient to protect against genetically diverse strains of the virus, according to a study conducted by investigators from the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health; Washington University in St. Louis; and Emory University in Atlanta.
NIH/National Institute of Allergy and Infectious Diseases

Contact: Jennifer Routh
NIH/National Institute of Allergy and Infectious Diseases

Public Release: 29-Jul-2016
Science Immunology
Tracking how HIV disrupts immune system informs vaccine development
One of the main mysteries confounding development of an HIV vaccine is why some people infected with the virus make the desired antibodies after several years, but a vaccine can't seem to induce the same response.
NIH/National Institute of Allergy and Infectious Diseases, Duke Center for HIV/AIDS Vaccine Immunology-Immunogen Discovery, MRC Programme Grant

Contact: Samiha Khanna
Duke University Medical Center

Public Release: 28-Jul-2016
PLOS Pathogens
INRS professor's team unveils new Leishmania virulence strategies
Professor Albert Descoteaux of INRS-Institut Armand-Frappier Research Centre and his team have discovered novel virulence strategies employed by the Leishmania parasite. These scientific breakthroughs recently published in the prestigious PLOS Pathogens journal represent two important clues to understanding the cellular and molecular mechanisms governing the parasitic infections that cause leishmaniasis, a neglected tropical disease endemic in one hundred countries.
Canadian Institutes of Health Research, Medical Research Council, Centre for Host-Parasite Interactions

Contact: Gisèle Bolduc
Institut national de la recherche scientifique - INRS

Public Release: 28-Jul-2016
Introduction of screening could significantly reduce lung cancer deaths
The introduction of lung cancer screening in the UK could significantly reduce deaths in high risk groups, without causing participants the undue stress sometimes associated with medical tests.

Contact: Julia Short
Cardiff University

Public Release: 28-Jul-2016
PLOS Pathogens
Open-source drug discovery a success
In what is being called the first-ever test of open-source drug-discovery, researchers from around the world have successfully identified compounds to pursue in treating and preventing parasite-borne illnesses such as malaria as well as cancer. The results have ignited more a dozen drug-development projects for a variety of diseases.
Medicines for Malaria Venture

Contact: Bobbi Nodell
University of Washington Health Sciences/UW Medicine

Public Release: 28-Jul-2016
PLOS Pathogens
Toward an effective TB vaccine: Analysis of the immune response to a promising candidate
BCG, the only currently approved TB vaccine, is only partially effective. Given the complicated TB treatment, the rise of adult TB cases in conjunction with the HIV epidemic, and increasing multidrug-resistant TB strains, a new and better vaccine is a global health priority. A study published on July 28 in PLOS Pathogens dissects the immune response in mice to an experimental vaccine and shows why it is highly effective.

Contact: Laleh Majlessi

Public Release: 27-Jul-2016
Neuropsychiatric Disease and Treatment
Zika virus challenges for neuropsychiatry recently published by Dove Medical Press
The Zika virus led the World Health Organization to declare the outbreak a global public health emergency in February 2016, but how much is really known about its neurobiology and potential neuropsychiatric manifestations?

Contact: Angela Jones
Dove Medical Press

Public Release: 27-Jul-2016
Studies in mice provide insights into antibody-Zika virus interactions
In research that could inform prophylactic treatment approaches for pregnant women at risk of Zika virus infection, investigators conducted experiments in mice and identified six Zika virus antibodies, including four that neutralize African, Asian and American strains of the mosquito-borne virus. The NIAID-supported team also developed atomic-level X-ray crystal structure images showing four of the antibodies in complex with three distinct regions (epitopes) of a key Zika protein.
NIH/National Institute of Allergy and Infectious Diseases

Contact: Anne A. Oplinger
NIH/National Institute of Allergy and Infectious Diseases

Showing releases 676-700 out of 1335.

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