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Disease in the Developing World

News Releases

Key: Meeting M      Journal J      Funder F

Showing releases 901-925 out of 1345.

<< < 32 | 33 | 34 | 35 | 36 | 37 | 38 | 39 | 40 | 41 > >>

Public Release: 26-Oct-2015
The Lancet
Stopping tuberculosis requires new strategy
Unless there is a major shift in the way the world fights tuberculosis -- from a reliance on biomedical solutions to an approach that combines biomedical interventions with social actions -- the epidemic and drug resistance will worsen, say researchers at Harvard T.H. Chan School of Public Health.
Wellcome Trust, National Institutes of Health

Contact: Todd Datz
Harvard T.H. Chan School of Public Health

Public Release: 22-Oct-2015
Cell Reports
How parasites take a bigger bite
A team of international scientists led by the Research Institute of the McGill University Health Centre uncovered an important mechanism behind Leishmania, a deadly parasitic disease transmitted by sandflies. In a new study published today in Cell Reports, researchers described how key molecules known as exosomes, boost the process by which the Leishmania parasite infects humans and other mammals. These findings could lead to the development of new potential vaccine targets and diagnostic tools.
Canadian Institutes of Health Research

Contact: Julie Robert
514-934-1934 x71381
McGill University Health Centre

Public Release: 22-Oct-2015
New England Journal of Medicine
NIH-funded study reveals why malaria vaccine only partially protected children, infants
Using new, highly sensitive genomic sequencing technology, an international team of researchers has found new biological evidence to help explain why the malaria vaccine candidate RTS,S/AS01 (called RTS,S) provided only moderate protection among vaccinated children during clinical testing. The researchers, funded in part by the National Institute of Allergy and Infectious Diseases at the National Institutes of Health, found that genetic variability in the surface protein targeted by the RTS,S vaccine likely played a significant role.
NIH/National Institute of Allergy and Infectious Diseases

Contact: Emily Mullin
NIH/National Institute of Allergy and Infectious Diseases

Public Release: 22-Oct-2015
Journal of Virological Methods
Bio-Rad's Droplet Digital™ PCR (ddPCR™) proves highly reproducible at identifying viral RNA mutations in clinical samples
Researchers show that droplet digital PCR is more sensitive, precise and reproducible at measuring viral RNA mutation rates in clinical samples than real-time PCR.

Contact: Ken Li
Chempetitive Group

Public Release: 22-Oct-2015
PLOS Pathogens
Interrupting the transmission cycle: A protein required for dengue virus infection of mosquitoes
An estimated 2 billion people are at risk for being bitten by Aedes mosquitoes and infected with the dengue virus (DENV). A study published on Oct. 22 in PLOS Pathogens introduces a candidate target for a transmission-blocking vaccine that interferes with virus infection of the mosquito after it feeds on the blood of infected hosts (such a vaccine would be a valuable complement to traditional DENV vaccines in development that seek to prevent human infection).

Contact: Tonya Colpitts

Public Release: 21-Oct-2015
American Society of Tropical Medicine & Hygiene
New England Journal of Medicine
Genomic study sheds light on protective effects of malaria vaccine candidate
An international team of researchers has used cutting edge genomic methods to uncover key biological insights that help explain the protective effects of the world's most advanced malaria vaccine candidate, RTS,S/AS01 (RTS,S). Applying highly sensitive sequencing technology to more patient samples than previously tested, the team was able to determine that genetic variation in the protein targeted by RTS,S influences the vaccine's ability to ward off malaria in young children.
NIh/National Institute of Allergy and Infectious Diseases, Bill & Melinda Gates Foundation, PATH Malaria Vaccine Initiative

Contact: Paul Goldsmith
Broad Institute of MIT and Harvard

Public Release: 21-Oct-2015
Parasites & Vectors
Leprosy and elephantiasis: New cases could be prevented in 10 years
The life chances of over one billion people could be improved through examining the transmission of nine neglected tropical diseases (NTDs), an international consortium of researchers has argued. Leprosy, Elephantiasis and Sleeping Sickness are among nine tropical diseases targeted. Neglected tropical diseases affect over one billion people worldwide.
Bill and Melinda Gates Foundation, The Novartis Foundation

Contact: Tom Frew
University of Warwick

Public Release: 21-Oct-2015
The Lancet
Worldwide shift in heart medication delivery required: Study
Many people in the world who need essential heart medicine do not get it, even in rich countries, says new research published today in the medical journal The Lancet. A radical change is required in how such medicines are provided and preventative care organized in health care systems, the authors say.
Population Health Research Institute, Canadian Institutes of Health Research, Heart and Stroke Foundation of Ontario, AstraZeneca, Sanofi-Aventis, Boehringer Ingelheim, Servier, GlaxoSmithKline, and others

Contact: Susan Emigh
905-525-9140 x22555
McMaster University

Public Release: 20-Oct-2015
PLOS Pathogens
Cancer-causing parasite may accelerate wound healing
James Cook University scientists have found a cancer-causing, parasitic worm could help patients recover from their wounds.

Contact: Alistair Bone
James Cook University

Public Release: 20-Oct-2015
Nature Communications
NIH study reveals risk of drug-resistant malaria spreading to Africa
Drug-resistant forms of Plasmodium falciparum, the deadliest species among malaria parasites, are able to infect the type of mosquito that is the main transmitter of malaria in Africa, according to findings from scientists at NIAID. The discovery suggests Africa -- where malaria will cause an estimated 400,000 deaths in 2015 -- is more at risk for drug-resistant malaria infections than previously thought, which could further compromise efforts to prevent and eliminate the disease.
NIH/National Institute of Allergy and Infectious Diseases

Contact: Jennifer Routh
NIH/National Institute of Allergy and Infectious Diseases

Public Release: 20-Oct-2015
Angewandte Chemie International Edition
First synthetic model of a bacterial outer membrane will support antibiotic development
Scientists have developed a model of the outer membrane of the bacteria E. coli (Escherichia coli) providing a brand new tool for developing new antibiotics and other drugs in the fight against infections.
Wellcome Trust

Contact: Karen Bidewell/Helen Rae
Newcastle University

Public Release: 19-Oct-2015
Malaria Journal
New approach toward a broad spectrum malaria vaccine
Malaria affects millions of people worldwide. Plasmodium falciparum enolase participates in parasite invasion of host red blood cells and mosquito midgut epithelium. Anti-enolase antibodies interfere with the invasion, inhibiting parasite growth and transmission. A pentapeptide insert of parasite enolase, conserved in all Plasmodia species, but absent from host enolases, shows considerable protection against malaria when displayed on Archaeal gas vesicle nanoparticles. A vaccine based on this motif could confer protection against all malaria parasites.
Tata Institute of Fundamental Research, Department of Atomic Energy, Government of India, National Institutes of Health, Bill and Melinda Gates Foundation

Contact: Gotam Jarori
Tata Institute of Fundamental Research

Public Release: 19-Oct-2015
Research!America to honor leaders in medical and health research advocacy
Research!America's 20th annual Advocacy Awards will honor exceptional advocates for research whose achievements in their fields have brought hope to patients worldwide. The event will take place on Wednesday, March 16, 2016, at the Andrew W. Mellon Auditorium in Washington, D.C.

Contact: Anna Briseno

Public Release: 19-Oct-2015
Mathematical Methods in the Applied Sciences
How chickens walk holds clues to how they spread disease
Plotting on a grid just how a chicken walks may one day give farmers more insight into how best to protect their flock from non-airborne pathogens that can also hurt their profit.

Contact: Toni Baker
Medical College of Georgia at Augusta University

Public Release: 15-Oct-2015
AIDS and Behavior
Researchers propose novel solution to HIV prevention
Enemas are commonly used by men who have sex with men (MSM) and transwomen (TW) before sexual intercourse. But these groups are vulnerable to HIV and other sexually transmitted infections (STIs) because enemas can seriously damage the thin tissue lining the rectum. A research group led by a UC Riverside assistant professor that worked recently with Peruvian MSM and TW proposes a rectal microbicide formulated as an enema to prevent HIV and possibly other STIs.
Merck & Co., Inc., National Institutes of Health

Contact: Iqbal Pittalwala
University of California - Riverside

Public Release: 15-Oct-2015
New England Journal of Medicine
Sexual transmission of Ebola virus in Liberia confirmed using genomic analysis
A suspected case of sexual transmission of Ebola virus disease in Liberia was confirmed using genomic analysis, thanks to in-country laboratory capabilities established by US Army scientists in collaboration with the Liberian Institute for Biomedical Research. The work, described in today's edition of the New England Journal of Medicine, provides molecular evidence of Ebola virus transmission between a disease survivor and his female partner. It also demonstrates the value of real-time genomic surveillance during an outbreak.
Defense Threat Reduction Agency, Global Biosurveillance Technology Initiative, Global Emerging Infections Surveillance, Illumina, NIH/National Institute of Allergy and Infectious Diseases, National Institutes of Health

Contact: Caree Vander Linden
US Army Medical Research Institute of Infectious Diseases

Public Release: 15-Oct-2015
IDRI, Sanofi Pasteur team with philanthropy to develop new model for vaccine development
In an effort to accelerate timelines and decrease development costs of life-saving vaccines, the Infectious Disease Research Institute and Sanofi Pasteur today announce the establishment of the Global Health Vaccine Center of Innovation, to be headquartered at IDRI in Seattle. This project is funded in part by a grant from the Bill & Melinda Gates Foundation.
Sanofi Pasteur, Bill and Melinda Gates Foundation

Contact: Lee Schoentrup
Infectious Disease Research Institute

Public Release: 15-Oct-2015
PLOS Neglected Tropical Diseases
Infection with 2 species of schistosome does not affect treatment efficacy
The parasitic disease schistosomiasis is caused by a trematode flatworm, different species of which can affect either the intestine or the urinary tract. Mixed species (co-) infections are common, and research is needed to understand exactly how infection by both urinary and intestinal parasites affects the course of infection and response to treatment.
European Union, Bill and Melinda Gates Foundation

Contact: Sarah C. L. Knowles

Public Release: 13-Oct-2015
Cancer Cell
Armed malaria protein found to kill cancer cells
In models of non-Hodgkin's lymphoma, castration-resistant prostate cancer, and metastatic breast cancer, the Kairos-VAR2 therapeutic demonstrated the ability to prevent tumor growth, regress established tumors, and cure metastatic disease. The studies were published today in the journal Cancer Cell.

Contact: John Babcook
The Centre for Drug Research and Development

Public Release: 13-Oct-2015
Scientific Reports
Antiviral favipiravir successfully treats Lassa virus in guinea pigs
Favipiravir, an investigational antiviral drug currently being tested in West Africa as a treatment for Ebola virus disease, effectively treated Lassa virus infection in guinea pigs, according to a new study from NIH scientists and colleagues.
NIH/National Institute of Allergy and Infectious Diseases

Contact: Ken Pekoc
NIH/National Institute of Allergy and Infectious Diseases

Public Release: 13-Oct-2015
In dryland African regions, limiting wildlife water access can reduce water quality
Water-dependent wildlife populations in sensitive African dryland regions need continued access to limited surface water resources -- even as human development increases in these areas -- because restricting access and concentrating wildlife populations along riparian regions can impact water quality and, potentially, human health.

Contact: Lynn Davis
Virginia Tech

Public Release: 13-Oct-2015
£3.5 million grant to improve prevention of tuberculosis in South African schoolchildren
The Medical Research Council has awarded a grant of £3.5 million to researchers from Queen Mary University of London and University of Cape Town to carry out a trial to determine whether a weekly vitamin D supplement can prevent tuberculosis in South African primary school children.
Medical Research Council

Contact: Rupert Marquand
Queen Mary University of London

Public Release: 13-Oct-2015
Nature Medicine
New study has important implications for the design of a protective HIV vaccine
A Ph.D. student from Wits University published a study describing how the changing viral swarm in an HIV infected person can drive the generation of antibodies able to neutralize HIV strains from across the world. The study has important implications for the design of a protective HIV vaccine.

Contact: Kemantha Govender
University of the Witwatersrand

Public Release: 13-Oct-2015
Nature Communications
Tulane researchers working on new tuberculosis vaccine
Researchers at the Tulane National Primate Research Center are leading efforts to find a new vaccine for tuberculosis, one of the world's deadliest diseases. A team of researchers led by the TNPRC used a modified strain of TB to show that monkeys could generate better protective immunity than when vaccinated with BCG, a common TB vaccine.
National Institutes of Health

Contact: Carolyn Scofield
Tulane University

Public Release: 13-Oct-2015
Cancer Cell
Destructive disease shows potential as a cancer treatment
Scientists at the University of British Columbia, Vancouver Coastal Health and the BC Cancer Agency have discovered a protein from malaria that could one day help stop cancer in its tracks.

Contact: Faydra Aldridge
604-875-4111 x66687
University of British Columbia

Showing releases 901-925 out of 1345.

<< < 32 | 33 | 34 | 35 | 36 | 37 | 38 | 39 | 40 | 41 > >>