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DOE is developing and delivering technologies for infrastructure security including chemical, biological, and nuclear nonproliferation and is assisting the country in preparing for, recognizing, and responding to attacks with such weapons.

DOE's Stockpile Stewardship Program provides the infrastructure and intellectual capability to maintain and certify weapons in our nation’s nuclear stockpile. DOE works to ensure the safety, security, reliability, affordability, and performance of nuclear weapons without underground testing. An essential component of this program is Advanced Simulation and Computing (ASC) formerly Accelerated Strategic Computing Initiative (ASCI).

ASC is creating simulation and prototyping capabilities based on advanced weapon codes and high-performance computing. The project integrates the efforts of three DOE national laboratories: Lawrence Livermore National Laboratory, Los Alamos National Laboratory, and Sandia National Laboratories in strategic partnerships with computer manufacturers and several of the nation's major universities.

DOE's Chemical and Biological Defense programs ( develop, demonstrate, and deliver technologies and systems that will help prevent the spread of chemical and biological weapons. These programs will help the nation prepare for, recognize, and respond to chemical and biological attacks on the civilian and military populations and the nation’s food supply.

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