11-Nov-2014 Researchers take snapshots of potential 'kill switch' for cancer
A study conducted in part at the Department of Energy's SLAC National Accelerator Laboratory has revealed how a key human protein switches from a form that protects cells to a form that kills them -- a property that scientists hope to exploit as a 'kill switch' for cancer.
17-Oct-2014 Atomic trigger shatters mystery of how glass deforms
A new study at the Department of Energy's Oak Ridge National Laboratory, published Sept. 24 in Nature Communications, has cracked one mystery of glass to shed light on the mechanism that triggers its deformation before shattering. The study improves understanding of glassy deformation and may accelerate broader application of metallic glass, a moldable, wear-resistant, magnetically exploitable material that is thrice as strong as the mightiest steel and ten times as springy.
6-Oct-2014 Study reveals 'bellhops' in cell walls can double as hormones
Researchers have discovered that some common messenger molecules in human cells double as hormones when bound to a protein that interacts with DNA. The finding could bring to light a class of previously unknown hormones and lead to new ways to target diseases -- including cancers and a host of hormone-related disorders.
22-Sep-2014 Research pinpoints role of 'helper' atoms in oxygen release
Experiments at the Department of Energy's SLAC National Accelerator Laboratory solve a long-standing mystery in the role calcium atoms serve in a chemical reaction that releases oxygen into the air we breathe. The results offer new clues about atomic-scale processes that drive the life-sustaining cycle of photosynthesis and could help forge a foundation for producing cleaner energy sources by synthesizing nature's handiwork.
4-Sep-2014 Scientists map protein in living bacterial cells
Scientists have for the first time mapped the atomic structure of a protein within a living cell. The technique, which peered into cells with an X-ray laser, could allow scientists to explore some components of living cells as never before. The research, published Aug. 18 in Proceedings of the National Academy of Sciences, was conducted at the Department of Energy's SLAC National Accelerator Laboratory.
2-Sep-2014 Researcher wins x-ray science award for SSRL work aiding chemistry studies
Chris Pollock, a postdoctoral researcher at The Pennsylvania State University, whose research at the Department of Energy's SLAC National Accelerator Laboratory was key in adapting an X-ray technique to probe chemical bonds in new ways, has been named the latest recipient of an annual scientific award.
22-Aug-2014 Catalytic gold nanoclusters promise rich chemical yields
With scientists from Carnegie Mellon University, researchers at the Department of Energy's Oak Ridge National Laboratory have found a catalyst containing exactly 25 gold atoms that catalyzes the conversion of various molecules, including the transformation of poisonous carbon monoxide into harmless carbon dioxide, a reaction that may find application in devices near gas flues or wood-burning stoves.
21-May-2014 Tethys: A robust source of information on marine energy, offshore wind projects
Wondering what the impact on killer whales might be from a turbine installed under the sea? Check out Tethys, a robust online resource available for free to anyone interested in ocean energy and offshore wind resources. Tethys focuses on the environmental effects of energy projects that are proposed, underway or completed in the ocean and above it.
6-May-2014 What lies beneath
The effects of biogeochemical and geochemical processes in the ground under us are on massive scales. Understanding what's going on down there and how it effects what's going on up here is an enormous undertaking. Scientists working at EMSL are getting a handle on these gigantic macroscopic processes by focusing on the microscopic scale. By creating micromodels and incorporating supercomputer simulations, researchers are connecting the molecular level with processes that affect our entire ecosystem.
29-Apr-2014 Label-free, sequence-specific, inexpensive fluorescent DNA sensors
Using principles of energy transfer more commonly applied to designing solar cells, scientists at the US Department of Energy's Brookhaven National Laboratory have developed a new highly sensitive way to detect specific sequences of DNA, the genetic material unique to every living thing. As described in a paper published in the journal Chemistry of Materials, the method is considerably less costly than other DNA assays and has widespread potential for applications in forensics, medical diagnostics, and the detection of bioterror agents.
11-Apr-2014 Simulation solves mystery of how liquid-crystal thin films disintegrate
Approximately four decades ago, theoreticians believed that only one of two mechanisms could explain rupture of liquid-crystal thin films. They also believed that these two mechanisms could not coexist. But 10 years ago experiments showed that these two mechanisms in many cases do coexist, according to Trung Nguyen of Oak Ridge National Laboratory, who ran unprecedented large-scale molecular dynamics simulations on Titan, America's fastest supercomputer, to model the beginnings of ruptures in thin films.
11-Apr-2014 Oak Ridge National Laboratory researchers contribute to prestigious climate report
Thomas Wilbanks and Benjamin Preston, both of the Climate Change Science Institute at Oak Ridge National Laboratory, are among the 309 coordinating lead authors of the Intergovernmental Panel on Climate Change's Working Group II report. The report, which was released in Japan on March 31, found that climate change isn't just a problem for future generations, but also impacts humans in the present day.
27-Mar-2014 Human-induced climate change reduces chance of flooding in Okavango Delta
Researchers at the University of Cape Town, Lawrence Berkeley National Laboratory and the United Nations Development Programme have analyzed how human-induced climate change has affected recent flooding in an ecologically and geographically unique river basin in southern Africa -- the Okavango River. After running a number of simulations, they found that greenhouse gas emissions have substantially reduced the chance of the floods in the region.
18-Mar-2014 Tapping into the metabolome
Metabolomics -- a field often called "the last 'omics frontier" -- seeks to understand the fundamental metabolic workings of a cell in a changing environment. Scientists at EMSL use mass spectrometers, nuclear magnetic resonance, imaging devices and other cutting-edge instruments to glean the information to help produce better fuels, crops and other bioproducts.
12-Mar-2014 Deep insights from thin layers
Imaging -- and understanding -- proteins may become a bit easier thanks to a team of researchers led by scientists at DOE's Pacific Northwest and Lawrence Livermore National Laboratories.
The Department of Energy's Office of Science is the single largest supporter of basic research in the physical sciences in the United States and is working to address some of the most pressing challenges of our time.