Showing stories 1-25 out of 59 stories. 1 | 2 | 3>>>
6-Jul-2017 ORNL researchers apply imaging, computational expertise to St. Jude research
In the quest to better understand and cure childhood diseases, scientists at St. Jude Children's Research Hospital accumulate enormous amounts of data from powerful video microscopes. To help St. Jude scientists mine that trove of data, researchers at Oak Ridge National Laboratory have created custom algorithms that can provide a deeper understanding of the images and quicken the pace of research.
8-Jun-2017 Tackling infectious disease -- one protein at a time
A team of scientists in the Pacific Northwest has solved the 3-D structure of 1,000 proteins from more than 70 organisms that cause infectious disease in people. The proteins the team has studied come from microbes that cause several serious diseases, including tuberculosis, Listeria, Giardia, Ebola, anthrax, C. diff., Legionella, Lyme, chlamydia and the flu.
19-May-2017 A fresh math perspective opens new possibilities for computational chemistry
A new mathematical "shortcut" developed by Berkeley Lab researchers is speeding up molecular absorption calculations by a factor of five, so simulations that used to take 10 to 15 hours to compute can now be done in approximately 2.5 hours. These algorithms will be incorporated in an upcoming release of the widely used NWChem computational chemistry software suite later this year.
27-Jan-2017 Art Rosenfeld, California's godfather of energy efficiency, dies at 90
Art Rosenfeld, a Lawrence Berkeley National Laboratory Distinguished Scientist Emeritus who is also known as California's 'godfather' of energy efficiency and who has been credited with being personally responsible for billions of dollars in energy savings, died Friday at his home in Berkeley, California. He was 90.
2-Nov-2016 Sandia to evaluate if computational neuroscientists are on track
The Intelligence Advanced Research Projects Activity (IARPA) launched the Machine Intelligence from Cortical Networks (MICrONS) project earlier this year. Sandia National Laboratories is refereeing the work of three university-led teams to map, understand and mathematically re-create visual processing in the brain to close the computer-human gap in object recognition.
17-May-2016 Lessons from cow eyes
Cornea tissue is a promising biomaterial for Brad Boyce, a Sandia National Laboratories materials scientist. More than a decade after Boyce and his co-workers investigated the biomechanics of dissected cow corneas, their findings have been confirmed in healthy human eyes.
28-Mar-2016 ORNL scientists show charged salts can extract specific central lanthanide elements
Researchers at Oak Ridge National Laboratory wanted to find out if it was possible to make a molecule that could selectively bind to metal cations in the middle of the lanthanide series. The team provided a proof-of-principle by successfully creating a new ligand that selectively extracted central lanthanides. Easier accessibility to these central lanthanides could lead to advances in materials for technologies such as lasers, strong magnets, lights and neutron-absorbing control rods in nuclear reactors.
21-Mar-2016 Sisters in science
Emma and Molly White and Ru-Shyan and Ru-Huey Yen, a pair of twin sisters and close friends who met in high school 16 years ago. Flash forward to today, and the four all have science-based careers, and look back at their shared-sisterhood-times-two as vital in getting them to where they are today.
14-Mar-2016 X-ray studies at SLAC and Berkeley Lab aid search for Ebola cure
In experiments carried out partly at the Department of Energy's SLAC National Accelerator Laboratory, scientists have determined in atomic detail how a potential drug molecule fits into and blocks a channel in cell membranes that Ebola and related 'filoviruses' need to infect victims' cells.
4-Jan-2016 Q&A: Biologist describes milestone toward a universal flu vaccine
Scientists from The Scripps Research Institute and the Crucell Vaccine Institute have now designed a protein fragment called mini-HA that stimulates the production of antibodies against a variety of influenza viruses. A key part of the work took place at the Stanford Synchrotron Radiation Lightsource, a DOE Office of Science User Facility at SLAC National Accelerator Laboratory, where the scientists used a technique called X-ray crystallography to look at the atomic structure of the mini-HA at each stage of its development.
9-Nov-2015 Molecular clocks control mutation rate in human cells
Every cell in the human body contains a copy of the human genome. Through the course of a lifetime all cells are thought to acquire mutations in their genomes. Some of the mutational processes generating these mutations do so in bursts and these will often be through external exposures such as sunbathing or tobacco smoking. Other mutational processes, however, may be internal to the cell and generate mutations continuously, at a constant rate over decades.
1-Sep-2015 Time-lapse analysis offers new look at how cells repair DNA damage
Time-lapse imaging can make complicated processes easier to grasp. Berkeley Lab scientists are using a similar approach to study how cells repair DNA damage. Microscopy images are acquired about every thirty minutes over a span of up to two days, and the resulting sequence of images shows ever-changing hotspots inside cells where DNA is under repair.
18-Aug-2015 Viral comparisons
An Oak Ridge National Laboratory team of comparative genomics and computational science researchers compared approximately 4,000 complete virus genomes downloaded from a public database known as GenBank. By compressing the sequence files, the team created a virus dendrogram that maps out the relationships among all the different virus families.
27-Jul-2015 Brookhaven Lab summer school helps develop tomorrow's nuclear chemistry experts
For the past six weeks, 12 college students have had the opportunity to learn all that the US Department of Energy's (DOE) Brookhaven National Laboratory has to teach about a vital but often overlooked area of chemistry -- one that spans everything from nuclear reactors and the safe handling of nuclear material to hospital diagnostic tools and cutting-edge medical research.
13-May-2015 Digitizing neurons
Supercomputing resources at Oak Ridge National Laboratory will support a new initiative designed to advance how scientists digitally reconstruct and analyze individual neurons in the human brain.
12-May-2015 Finding the missing particles
For the past 20 years, a large portion of the particles measured in the atmosphere were missing from models. At best, models were able to explain one-tenth of the carbon-rich secondary organic aerosols measured in the air. The problem turned out to be a series of fundamental assumptions used in the models due to a lack of experimental data. All of the assumptions were proven false by Dr. Alla Zelenyuk and her colleagues.
The Department of Energy's Office of Science is the single largest supporter of basic research in the physical sciences in the United States and is working to address some of the most pressing challenges of our time.