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DOE NEWS RELEASES

Key: Meeting M      Journal J      Funder F

Showing releases 1-25 out of 42.

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Public Release: 16-Oct-2017
SimPath licenses novel ORNL system for enhanced synthetic biology
SimPath has licensed a novel cloning system developed by the Department of Energy's Oak Ridge National Laboratory that generates and assembles the biological building blocks necessary to synthetically bioengineer new medicines and fuels.
US Department of Energy, Biological and Environmental Research, Genomic Science Program; ORNL's Technology Innovation Program

Contact: Sara Shoemaker
shoemakerms@ornl.gov
865-576-9219
DOE/Oak Ridge National Laboratory

Public Release: 16-Oct-2017
ESnet's science DMZ design could help transfer, protect medical research data
As medicine becomes more data-intensive, Berkeley Lab & ESnet's Medical Science DMZ eyed as secure solution for transferring data.

Contact: Jon Bashor
jbashor@lbl.gov
510-486-5849
DOE/Lawrence Berkeley National Laboratory

Public Release: 16-Oct-2017
Nature Communications
Neutrons observe vitamin B6-dependent enzyme activity useful for drug development
Scientists at the Department of Energy's Oak Ridge National Laboratory have performed neutron structural analysis of a vitamin B6-dependent protein, potentially opening avenues for new antibiotics and drugs to battle diseases such as drug-resistant tuberculosis, malaria and diabetes. Specifically, the team used neutron crystallography to study the location of hydrogen atoms in aspartate aminotransferase, or AAT, an enzyme vital to the metabolism of certain amino acids.
Department of Energy's Office of Science, ORNL's Center for Structural Molecular Biology

Contact: Sara Shoemaker
shoemakerms@ornl.gov
865-576-9219
DOE/Oak Ridge National Laboratory

Public Release: 11-Oct-2017
Nature Communications
Tracking the viral parasites of giant viruses over time
In freshwater lakes, microbes regulate the flow of carbon and determine if the bodies of water serve as carbon sinks or carbon sources. Viruses exist amidst all bacteria, usually in a 10-fold excess and include virophages which live in giant viruses and use their machinery to replicate and spread. Reported in Nature Communications, researchers at The Ohio State University and the DOE Joint Genome Institute have effectively doubled the number of known virophages.
DOE/Office of Science

Contact: David Gilbert
degilbert@lbl.gov
DOE/Joint Genome Institute

Public Release: 2-Oct-2017
Painless microneedles extract fluid for wearable sensors for soldiers, athletes
Microneedles are the first way to extract large volumes of pure interstitial fluid. This fluid can be used to track the physical conditions of athletes, soldiers, even diabetics but could also aid in diagnosing other diseases, including cancer.

Contact: Mollie Rappe
mrappe@sandia.gov
505-844-8220
DOE/Sandia National Laboratories

Public Release: 20-Sep-2017
Sandia Labs wins 5 regional technology transfer awards
Sandia National Laboratories won five awards from the 2017 Federal Laboratory Consortium for its work to develop and commercialize innovative technologies. The annual FLC awards program recognizes federal laboratories and their industry partners for outstanding technology transfer achievements.

Contact: Sue Holmes
sholmes@sandia.gov
505-844-6362
DOE/Sandia National Laboratories

Public Release: 24-Aug-2017
PLOS ONE
DNA detectives crack the case on biothreat look-alikes
Biological "detectives" are tracking down biothreats such as the bacteria that causes tularemia ("rabbit fever"), but they constantly face the challenge of avoiding false positives.

Contact: Nancy Ambrosiano
nwa@lanl.gov
505-667-0471
DOE/Los Alamos National Laboratory

Public Release: 14-Aug-2017
EPJ Data Science
Are your tweets feeling well?
A study finds opinion and emotion in tweets change when you get sick, a method that public health workers could use to monitor health trends.
Defense Threat Reduction Agency

Contact: Eric Francavilla
eric.francavilla@pnnl.gov
509-372-4066
DOE/Pacific Northwest National Laboratory

Public Release: 9-Aug-2017
PLOS ONE
Exposure to antimicrobials during development may cause irreversible outcomes
Lawrence Livermore National Laboratory scientists have discovered that exposure to environmental levels of triclocarban (TCC), an antibacterial chemical common in personal care products like soaps and lotions as well as in the medical field, can transfer from mother to offspring and interfere with lipid metabolism.

Contact: Anne Stark
stark8@llnl.gov
925-422-9799
DOE/Lawrence Livermore National Laboratory

Public Release: 27-Jul-2017
Science
Seeing more with PET scans: New chemistry for medical imaging
Researchers have found a surprisingly versatile workaround to create chemical compounds that could prove useful for medical imaging and drug development.

Contact: Jon Weiner
jrweiner@lbl.gov
510-486-4014
DOE/Lawrence Berkeley National Laboratory

Public Release: 11-Jul-2017
Clean water that's 'just right' with Sandia sensor solution
Working with Parker Hannifin, Sandia National Laboratories combined basic research on an interesting form of carbon with a unique microsensor to make an easy-to-use, table-top tool that quickly and cheaply detects disinfection byproducts in our drinking water before it reaches consumers.

Contact: Mollie Rappe
mrappe@sandia.gov
505-844-8220
DOE/Sandia National Laboratories

Public Release: 10-Jul-2017
Proceedings of the National Academy of Sciences
New Berkeley lab algorithms extract biological structure from limited data
A new Berkeley Lab algorithmic framework called multi-tiered iterative phasing (M-TIP) utilizes advanced mathematical techniques to determine 3-D molecular structure of important nanoobjects like proteins and viruses from very sparse sets of noisy, single-particle data.

Contact: Linda Vu
lvu@lbl.gov
510-495-2402
DOE/Lawrence Berkeley National Laboratory

Public Release: 5-Jul-2017
Nature Climate Change
Story tips from the Department of Energy's Oak Ridge National Laboratory, July 2017
ORNL-led team integrates Earth systems with human impact data for climate predictions with fewer uncertainties; ORNL to develop secure platform to analyze large health datasets for Dept. of Veterans Affairs; ORNL neutrons used to resolve debate over origins of metallic glass behavior; ORNL studies 3-D printing materials that crosslink without heat; New web-based calculator by ORNL shows energy-savings potential of airtight buildings; ORNL combines 3-D printing with casting to produce multi-material, damage-tolerant components.
Department of Energy

Contact: Sara Shoemaker
shoemakerms@ornl.gov
865-576-9219
DOE/Oak Ridge National Laboratory

Public Release: 28-Jun-2017
Scientific Reports
What's on your skin? Archaea, that's what
It turns out your skin is crawling with single-celled microorganisms -- and they're not just bacteria. A study by the Department of Energy's Lawrence Berkeley National Laboratory (Berkeley Lab) and the Medical University of Graz has found that the skin microbiome also contains archaea, a type of extreme-loving microbe, and that the amount of it varies with age.
Department of Energy, BioTechMed Graz, Bavaria California Technology Center, University of Regensburg

Contact: Julie Chao
jhchao@lbl.gov
510-486-6491
DOE/Lawrence Berkeley National Laboratory

Public Release: 28-Jun-2017
Protein data takes significant step forward in medicine
Scientists at the Pacific Northwest National Laboratory and Oregon Health & Science University are part of a nationwide effort to learn more about the role of proteins in cancer biology and to use that information to benefit cancer patients.
NIH/National Cancer Institute

Contact: Tom Rickey
tom.rickey@pnnl.gov
DOE/Pacific Northwest National Laboratory

Public Release: 13-Jun-2017
Science
Argonne X-rays used to help identify a key Lassa virus structure
Research done at Argonne National Laboratory's Advanced Photon Source was vital to the process of identifying the structure, which provides a guide for designing a Lassa virus vaccine. Lassa virus is endemic to Africa and kills thousands of people a year; it is particularly deadly for pregnant women.

Contact: Karen Mellen
kmellen@anl.gov
630-252-5325
DOE/Argonne National Laboratory

Public Release: 31-May-2017
Science Advances
Newly identified microbial process could reduce toxic methylmercury levels
A team led by the Department of Energy's Oak Ridge National Laboratory has identified a novel microbial process that can break down toxic methylmercury in the environment, a fundamental scientific discovery that could potentially reduce mercury toxicity levels and support health and risk assessments.
DOE/Office of Biological and Environmental Research

Contact: Sara Shoemaker
shoemakerms@ornl.gov
865-576-9219
DOE/Oak Ridge National Laboratory

Public Release: 2-May-2017
Nature Communications
Story tips from the Department of Energy's Oak Ridge National Laboratory, May 2017
Oak Ridge National Laboratory aids St. Jude's brain development research with software to speed processing of microscopy images; a bottleneck in the process to breakdown lignin for use in biofuels may occur at the plant cell wall's surface; predicting how ecosystems respond to environmental change could become more precise through new process sensitivity index method; through "quantum mechanical squeezing," researchers have conceptually designed a new method to increase the resolution of atomic force microscopy.
NIH/National Institute Of Neurological Disorders

Contact: Sara Shoemaker
shoemakerms@ornl.gov
865-576-9219
DOE/Oak Ridge National Laboratory

Public Release: 25-Apr-2017
Scientific Reports
Managing disease spread through accessible modeling
A new computer modeling study from Los Alamos National Laboratory is aimed at making epidemiological models more accessible and useful for public-health collaborators and improving disease-related decision making.
Defense Threat Reduction Agency

Contact: Nancy Ambrosiano
nwa@lanl.gov
505-667-0471
DOE/Los Alamos National Laboratory

Public Release: 24-Apr-2017
Neuropsychologia
Research from Sandia shows brain stimulation during training boosts performance
New research from Sandia published in Neuropsychologia shows that working memory training combined with a kind of noninvasive brain stimulation can lead to cognitive improvement under certain conditions. Improving working memory or cognitive strategies could be very valuable for training people faster and more efficiently.

Contact: Mollie Rappe
mrappe@sandia.gov
505-844-8220
DOE/Sandia National Laboratories

Public Release: 20-Apr-2017
Sandia honored for fighting Ebola, analyzing emerging biotechnologies
Researchers at Sandia National Laboratories just received recognition from the Secretary of Energy for their work to mitigate the effects of the 2014 Ebola epidemic.

Contact: Mollie Rappe
mrappe@sandia.gov
505-844-8220
DOE/Sandia National Laboratories

Public Release: 17-Apr-2017
Nature Materials
Tweaking a molecule's structure can send it down a different path to crystallization
Silky chocolate, a better medical drug, or solar panels all require the same thing: just the right crystals making up the material. Now, scientists trying to understand the paths crystals take as they form have been able to influence that path by modifying the starting ingredient.
US Department of Energy

Contact: Mary Beckman
mary.beckman@pnnl.gov
509-375-3688
DOE/Pacific Northwest National Laboratory

Public Release: 10-Apr-2017
Nature Communications
Researchers gain insight into protein critical to Zika virus reproduction
Berkeley Lab researchers collaborated with colleagues from the University of Indiana and Texas A&M University to solve the atomic structure of a Zika virus protein that is key to viral reproduction. The X-ray studies were conducted at the Advanced Light Source in the Berkeley Center for Structural Biology.
National Institutes of Health, Howard Hughes Medical Institute

Contact: Jon Weiner
jrweiner@lbl.gov
510-486-4014
DOE/Lawrence Berkeley National Laboratory

Public Release: 6-Apr-2017
Science
Discovered: Novel group of giant viruses
Viruses are thought to outnumber the microbes on Earth; both outnumber the stars in the Milky Way. A handful of giant viruses have been discovered in the past two decades, and in Science, DOE Joint Genome Institute scientists report a novel group of giant viruses with a more complete set of translation machinery genes than any other virus known to date. They believe that this discovery significantly increases our understanding of viral evolution.
DOE/Office of Science

Contact: David Gilbert
degilbert@lbl.gov
924-296-5643
DOE/Joint Genome Institute

Public Release: 5-Apr-2017
Nature
X-ray study reveals long-sought insights into potential drug target
X-ray studies done in part at the Department of Energy's SLAC National Accelerator Laboratory have produced surprising insights into the workings of a hormone receptor associated with blood pressure regulation. Researchers believe it could be a target for new medicines related to cardiovascular conditions, neuropathic pain and tissue growth.
National Institutes of Health, National Science Foundation, DOE/Office of Science

Contact: Andy Freeberg
afreeberg@slac.stanford.edu
650-926-4359
DOE/SLAC National Accelerator Laboratory

Showing releases 1-25 out of 42.

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