Researchers report that the S protein of porcine deltacoronavirus (PDCoV) bound to a domain of the protein aminopeptidase N (APN), which is expressed on the surface of host cells and is highly conserved across animal species; expression of APN from pigs, humans, chickens, and cats facilitated PDCoV infection of cultured cells, suggesting a possible mechanism of PDCoV transmission from pigs to other species.
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Article #18-02879: "Broad receptor engagement of an emerging global coronavirus may potentiate its diverse cross-species transmissibility," by Wentao Li et al.
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Journal
Proceedings of the National Academy of Sciences