How drugs can bind to the TAAR1 receptor (IMAGE)

The Mount Sinai Hospital / Mount Sinai School of Medicine

How drugs can bind to the TAAR1 receptor

Caption

Mount Sinai Icahn scientists took detailed pictures of how drugs can bind to the TAAR1 receptor using CryoEM. They also discovered that an antipsychotic drug, asenapine, unexpectedly activates TAAR1, which could potentially contribute to asenapine’s therapeutic effects.

Credit

Wacker et al., Nature Communications

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