Trends in pancreatic islet cell loss. (IMAGE) Tokyo Metropolitan University Caption (top left and right) Two different ways in which islet cell loss can be observed. (bottom left) The relationship between the percentage of pancreatic beta cells and islet cell loss. (bottom right) The number of mild and severe cases of ICL at different ages. Credit Tokyo Metropolitan University Usage Restrictions Pease give credit for use. License Original content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.